RANBP2 evolution and human disease

Structure of the nuclear pore complex goes atomic

(2023) Gaoxingyu Huang et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Pediatric recurrent acute necrotizing encephalomyelitis, RANBP2 genotype and Sars-CoV-2 infection: Diagnosis, pathogenesis and targeted treatments from a case study

(2023) Cristina Forest et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

A quantitative map of nuclear pore assembly reveals two distinct mechanisms

(2023) Shotaro Otsuka et al.   NATURE

Cryo-electron Microscopy Reveals the Structure of the Nuclear Pore Complex

(2023) Linhua Tai et al.   JOURNAL OF MOLECULAR BIOLOGY

CSF neopterin and quinolinic acid are biomarkers of neuroinflammation and neurotoxicity in FIRES and other infection‐triggered encephalopathy syndromes

(2023) Russell C. Dale et al.   Annals of Clinical and Translational Neurology

Comprehensive structure and functional adaptations of the yeast nuclear pore complex

(2022) Christopher W. Akey et al.   CELL

Outcomes in influenza and RANBP2 mutation‐associated acute necrotizing encephalopathy of childhood

(2022) Nurin Chatur et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Karyopherin-mediated nucleocytoplasmic transport

(2022) Casey E. Wing et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

8 Å structure of the outer rings of the Xenopus laevis nuclear pore complex obtained by cryo-EM and AI

(2022) Linhua Tai et al.   Protein & Cell

Roles of Nucleoporin RanBP2/Nup358 in Acute Necrotizing Encephalopathy Type 1 (ANE1) and Viral Infection

(2022) Jing Jiang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Workshop on RanBP2/Nup358 and acute necrotizing encephalopathy

(2022) Alexander F. Palazzo et al.   Nucleus

COVID-19 related acute necrotizing encephalopathy with extremely high interleukin-6 and RANBP2 mutation in a patient with recently immunized inactivated virus vaccine and no pulmonary involvement

(2022) Thanakit Pongpitakmetha et al.   BMC INFECTIOUS DISEASES

Tau–FG-nucleoporin98 interaction and impaired nucleocytoplasmic transport in Alzheimer’s disease

(2022) Niharika Nag et al.   Briefings in Functional Genomics

Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold

(2022) Pietro Fontana et al.   SCIENCE

Architecture of the cytoplasmic face of the nuclear pore

(2022) Christopher J. Bley et al.   SCIENCE

Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex

(2022) Xuechen Zhu et al.   SCIENCE

AI-based structure prediction empowers integrative structural analysis of human nuclear pores

(2022) Shyamal Mosalaganti et al.   SCIENCE

Structure and Function of the Nuclear Pore Complex

(2022) Stefan Petrovic et al.   Cold Spring Harbor Perspectives in Biology

Targeting Nup358/RanBP2 by a viral protein disrupts stress granule formation

(2022) Jibin Sadasivan et al.   PLoS Pathogens

Cone-shaped HIV-1 capsids are transported through intact nuclear pores

(2021) Vojtech Zila et al.   CELL

One Ring to Rule them All? Structural and Functional Diversity in the Nuclear Pore Complex

(2021) Javier Fernandez-Martinez et al.   TRENDS IN BIOCHEMICAL SCIENCES

RanBP2/Nup358 enhances miRNA activity by sumoylating Argonautes

(2021) Qingtang Shen et al.   PLoS Genetics

Annulate lamellae and intracellular pathogens

(2021) Sébastien Eymieux et al.   CELLULAR MICROBIOLOGY

YTHDF1 Aggravates the Progression of Cervical Cancer Through m6A-Mediated Up-Regulation of RANBP2

(2021) Haocheng Wang et al.   Frontiers in Oncology

Acute necrotizing encephalopathy-linked mutations in Nup358 impair interaction of Nup358 with TNRC6/GW182 and miRNA function

(2021) Prachi Deshmukh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The miRISC component AGO2 has multiple binding sites for Nup358 SUMO-interacting motif

(2021) Prachi Deshmukh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evolution and diversification of the nuclear pore complex

(2021) Alexandr A. Makarov et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mitotic disassembly and reassembly of nuclear pore complexes

(2021) Ulrike Kutay et al.   TRENDS IN CELL BIOLOGY

RANBP2 Activates O-GlcNAcylation through Inducing CEBPα-Dependent OGA Downregulation to Promote Hepatocellular Carcinoma Malignant Phenotypes

(2021) Xiaoming Liu et al.   Cancers

RANBP2 mutation causing autosomal dominant acute necrotizing encephalopathy attenuates its interaction with COX11

(2021) Akiko Shibata et al.   NEUROSCIENCE LETTERS

The RanBP2 zinc finger domains of chloroplast RNA editing factor OZ1 are required for protein–protein interactions and conversion of C to U

(2021) Andrew B. Gipson et al.   PLANT JOURNAL

Association of RanGAP to nuclear pore complex component, RanBP2/Nup358, is required for pupal development in Drosophila

(2021) Shane Chen et al.   Cell Reports

Nup358 and Transportin 1 Cooperate in Adenoviral Genome Import

(2020) Irene Carlon-Andres et al.   JOURNAL OF VIROLOGY

Genetic Acute Necrotizing Encephalopathy Associated with RANBP2: Clinical and Therapeutic Implications in Pediatrics

(2020) Jesse M. Levine et al.   Multiple Sclerosis and Related Disorders

Nucleo–cytoplasmic transport defects and protein aggregates in neurodegeneration

(2020) Giacomo Bitetto et al.   Translational Neurodegeneration

The Structure of the Nuclear Pore Complex (An Update)

(2019) Daniel H. Lin et al.   Annual Review of Biochemistry

Structure and Assembly of the Nuclear Pore Complex

(2019) Bernhard Hampoelz et al.   Annual Review of Biophysics

Adapter Proteins for Opposing Motors Interact Simultaneously with Nuclear Pore Protein Nup358

(2019) Heying Cui et al.   BIOCHEMISTRY

Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis

(2019) Bernhard Hampoelz et al.   CELL

Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease

(2018) Bahareh Eftekharzadeh et al.   NEURON

Exploitation of nuclear functions by human rhinovirus, a cytoplasmic RNA virus

(2018) Dylan Flather et al.   PLoS Pathogens

Selective recruitment of nucleoporins on vaccinia virus factories and the role of Nup358 in viral infection

(2017) Deepak Khuperkar et al.   VIROLOGY

Variable clinical course in acute necrotizing encephalopathy and identification of a novel RANBP2 mutation

(2016) Katharina Sell et al.   BRAIN & DEVELOPMENT

The Nuclear Pore Complex as a Flexible and Dynamic Gate

(2016) Kevin E. Knockenhauer et al.   CELL

Nup358 binds to AGO proteins through its SUMO‐interacting motifs and promotes the association of target mRNA with miRISC

(2016) Manas Ranjan Sahoo et al.   EMBO REPORTS

The nuclear pore complex: understanding its function through structural insight

(2016) Martin Beck et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells

(2016) Débora M. Portilho et al.   Cell Reports

KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection

(2016) Adarsh Dharan et al.   PLoS Pathogens

Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex

(2015) Volkan Sakin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRIM5α is a SUMO substrate

(2015) Jacques Dutrieux et al.   Retrovirology

Familial acute necrotizing encephalopathy due to mutation in the RANBP2 gene

(2014) Christian Denier et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Mechanisms of mRNA export

(2014) Petra Björk et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

RanBP2/Nup358 Potentiates the Translation of a Subset of mRNAs Encoding Secretory Proteins

(2014) Kohila Mahadevan et al.   PLOS BIOLOGY

Structural and Functional Analysis of the C-Terminal Domain of Nup358/RanBP2

(2013) Daniel H. Lin et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of Host Proteins Involved in Japanese Encephalitis Virus Infection by Quantitative Proteomics Analysis

(2013) Lei-Ke Zhang et al.   JOURNAL OF PROTEOME RESEARCH

Reduced RAN Expression and Disrupted Transport between Cytoplasm and Nucleus; A Key Event in Alzheimer’s Disease Pathophysiology

(2013) Diego Mastroeni et al.   PLoS One

HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358

(2013) Katsiaryna Bichel et al.   Retrovirology

Hepatitis C Virus-Induced Cytoplasmic Organelles Use the Nuclear Transport Machinery to Establish an Environment Conducive to Virus Replication

(2013) Christopher J. Neufeldt et al.   PLoS Pathogens

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

(2012) Kyoung-in Cho et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Crystal Structure of the N-Terminal Domain of Nup358/RanBP2

(2012) Susanne A. Kassube et al.   JOURNAL OF MOLECULAR BIOLOGY

Into the Eye of the Cytokine Storm

(2012) J. R. Tisoncik et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2

(2012) Noriko Saitoh et al.   MOLECULAR BIOLOGY OF THE CELL

Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions

(2012) Marcela Raices et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration

(2012) Francesca Di Nunzio et al.   PLoS One

The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic Transformation

(2012) Biljana Culjkovic-Kraljacic et al.   Cell Reports

Kinesin-1-Mediated Capsid Disassembly and Disruption of the Nuclear Pore Complex Promote Virus Infection

(2011) Sten Strunze et al.   Cell Host & Microbe

β-Catenin Inhibits Promyelocytic Leukemia Protein Tumor Suppressor Function in Colorectal Cancer Cells

(2011) Reiko Satow et al.   GASTROENTEROLOGY

Ran-dependent docking of importin-β to RanBP2/Nup358 filaments is essential for protein import and cell viability

(2011) Masakazu Hamada et al.   JOURNAL OF CELL BIOLOGY

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Gene Regulation by Nucleoporins and Links to Cancer

(2010) Alwin Köhler et al.   MOLECULAR CELL

The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition

(2010) Jaclyn R. Gareau et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Acute Necrotizing Encephalopathy in 3 Brothers

(2010) E. J. Marco et al.   PEDIATRICS

Perturbation of Host Nuclear Membrane Component RanBP2 Impairs the Nuclear Import of Human Immunodeficiency Virus -1 Preintegration Complex (DNA)

(2010) Ruonan Zhang et al.   PLoS One

Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins

(2010) J. R. A. Hutchins et al.   SCIENCE

Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulate Centrosome and Nuclear Positioning during Mitotic Entry

(2010) Daniël Splinter et al.   PLOS BIOLOGY

Infection-Triggered Familial or Recurrent Cases of Acute Necrotizing Encephalopathy Caused by Mutations in a Component of the Nuclear Pore, RANBP2

(2009) Derek E. Neilson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

The nuclear pore component Nup358 promotes transportin-dependent nuclear import

(2009) S. Hutten et al.   JOURNAL OF CELL SCIENCE

Resolution of Sister Centromeres Requires RanBP2-Mediated SUMOylation of Topoisomerase IIα

(2008) Meelad M. Dawlaty et al.   CELL

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Nuclear Pore Composition and Gating in Herpes Simplex Virus-Infected Cells

(2008) H. Hofemeister et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Replication: Roles of Viral Proteins and Nucleoporins in Capsid-Nucleus Attachment

(2008) A. M. Copeland et al.   JOURNAL OF VIROLOGY

The Nup358-RanGAP Complex Is Required for Efficient Importin α/β-dependent Nuclear Import

(2008) Saskia Hutten et al.   MOLECULAR BIOLOGY OF THE CELL

RanBP2 and SENP3 Function in a Mitotic SUMO2/3 Conjugation-Deconjugation Cycle on Borealin

(2008) Ulf R. Klein et al.   MOLECULAR BIOLOGY OF THE CELL