Evolution and diversification of the nuclear pore complex

Evolution and diversification of the nuclear envelope

(2021) Norma E. Padilla-Mejia et al.   Nucleus

One Ring to Rule them All? Structural and Functional Diversity in the Nuclear Pore Complex

(2021) Javier Fernandez-Martinez et al.   TRENDS IN BIOCHEMICAL SCIENCES

A designer FG-Nup that reconstitutes the selective transport barrier of the nuclear pore complex

(2021) Alessio Fragasso et al.   Nature Communications

Into the basket and beyond: the journey of mRNA through the nuclear pore complex

(2020) Asaf Ashkenazy-Titelman et al.   BIOCHEMICAL JOURNAL

Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex by cryo-electron microscopy single particle analysis

(2020) Gaoxingyu Huang et al.   CELL RESEARCH

Molecular architecture of the luminal ring of the Xenopus laevis nuclear pore complex

(2020) Yanqing Zhang et al.   CELL RESEARCH

Selective Nuclear Pore Complex Removal Drives Nuclear Envelope Division in Fission Yeast

(2020) María Expósito-Serrano et al.   CURRENT BIOLOGY

Closed mitosis requires local disassembly of the nuclear envelope

(2020) Gautam Dey et al.   NATURE

In-cell architecture of the nuclear pore and snapshots of its turnover

(2020) Matteo Allegretti et al.   NATURE

TPR is required for the efficient nuclear export of mRNAs and lncRNAs from short and intron-poor genes

(2020) Eliza S Lee et al.   NUCLEIC ACIDS RESEARCH

Nucleoporin TPR is an integral component of the TREX-2 mRNA export pathway

(2020) Vasilisa Aksenova et al.   Nature Communications

Genomic identification and expression analysis of nuclear pore proteins in Malus domestica

(2020) Chenguang Zhang et al.   Scientific Reports

Emerging molecular functions and novel roles for the DEAD-box protein Dbp5/DDX19 in gene expression

(2020) Arvind Arul Nambi Rajan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nucleoporin NUP205 plays a critical role in cilia and congenital disease

(2020) Jonathan Marquez et al.   DEVELOPMENTAL BIOLOGY

Yeast Nup84-Nup133 complex structure details flexibility and reveals conservation of the membrane anchoring ALPS motif

(2020) Sarah A. Nordeen et al.   Nature Communications

The deubiquitylase Ubp15 couples transcription to mRNA export

(2020) Fanny Eyboulet et al.   eLife

Structure of the human core transcription-export complex reveals a hub for multivalent interactions

(2020) Thomas Pühringer et al.   eLife

Nuclear Pore Membrane Proteins Self-Assemble into Nanopores

(2019) Radhakrishnan Panatala et al.   BIOCHEMISTRY

The nuclear envelope in higher plant mitosis and meiosis

(2019) Monica Pradillo et al.   Nucleus

The mRNA Export Receptor NXF1 Coordinates Transcriptional Dynamics, Alternative Polyadenylation, and mRNA Export

(2019) Suli Chen et al.   MOLECULAR CELL

Extensive Reduction of the Nuclear Pore Complex in Nucleomorphs

(2019) Nicholas A T Irwin et al.   Genome Biology and Evolution

The Structure of the Nuclear Pore Complex (An Update)

(2019) Daniel H. Lin et al.   Annual Review of Biochemistry

The Lotus japonicus nucleoporin GLE1 is involved in symbiotic association with rhizobia

(2019) Akito Imai et al.   PHYSIOLOGIA PLANTARUM

Chromatin targeting of nuclear pore proteins induces chromatin decondensation

(2019) Terra M. Kuhn et al.   JOURNAL OF CELL BIOLOGY

Asymmetrical localization of Nup107-160 subcomplex components within the nuclear pore complex in fission yeast

(2019) Haruhiko Asakawa et al.   PLoS Genetics

Imaging within single NPCs reveals NXF1’s role in mRNA export on the cytoplasmic side of the pore

(2019) Rakefet Ben-Yishay et al.   JOURNAL OF CELL BIOLOGY

Unique Interactions of the Nuclear Export Receptors TbMex67 and TbMtr2 with Components of the 5S Ribonuclear Particle in Trypanosoma brucei

(2019) Constance Rink et al.   mSphere

The RNA export factor Mex67 functions as a mobile nucleoporin

(2019) Carina Patrizia Derrer et al.   JOURNAL OF CELL BIOLOGY

Core Components of the Nuclear Pore Bind Distinct States of Chromatin and Contribute to Polycomb Repression

(2019) Alejandro Gozalo et al.   MOLECULAR CELL

Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance

(2019) Nahid Iglesias et al.   MOLECULAR CELL

Allosteric modulation of nucleoporin assemblies by intrinsically disordered regions

(2019) Bartlomiej Jan Blus et al.   Science Advances

A streamlined cohesin apparatus is sufficient for mitosis and meiosis in the protist Tetrahymena

(2018) Emine I. Ali et al.   CHROMOSOMA

NUP98 Sets the Size-Exclusion Diffusion Limit through the Ciliary Base

(2018) S. Joseph Endicott et al.   CURRENT BIOLOGY

Seh1 targets GATOR2 and Nup153 to mitotic chromosomes

(2018) Melpomeni Platani et al.   JOURNAL OF CELL SCIENCE

The Adaptor Protein ENY2 Is a Component of the Deubiquitination Module of the Arabidopsis SAGA Transcriptional Co-activator Complex but not of the TREX-2 Complex

(2018) Alexander Pfab et al.   JOURNAL OF MOLECULAR BIOLOGY

mRNA export in the apicomplexan parasite Toxoplasma gondii: emerging divergent components of a crucial pathway

(2018) Andréa Rodrigues Ávila et al.   Parasites & Vectors

ALY RNA-binding proteins are required for nucleo-cytosolic mRNA transport and modulate plant growth and development

(2018) Christina Pfaff et al.   PLANT PHYSIOLOGY

Structural and functional analysis of mRNA export regulation by the nuclear pore complex

(2018) Daniel H. Lin et al.   Nature Communications

In situ architecture of the algal nuclear pore complex

(2018) Shyamal Mosalaganti et al.   Nature Communications

Integrative structure and functional anatomy of a nuclear pore complex

(2018) Seung Joong Kim et al.   NATURE

Electron microscopy of Chaetomium pom152 shows the assembly of ten-bead string

(2018) Qi Hao et al.   Cell Discovery

Nup98 recruits the Wdr82–Set1A/COMPASS complex to promoters to regulate H3K4 trimethylation in hematopoietic progenitor cells

(2017) Tobias M. Franks et al.   GENES & DEVELOPMENT

Nonrandom domain organization of the Arabidopsis genome at the nuclear periphery

(2017) Xiuli Bi et al.   GENOME RESEARCH

Compositionally distinct nuclear pore complexes of functionally distinct dimorphic nuclei in the ciliateTetrahymena

(2017) Masaaki Iwamoto et al.   JOURNAL OF CELL SCIENCE

Structure of the Sac3 RNA-binding M-region in the Saccharomyces cerevisiae TREX-2 complex

(2017) James M. B. Gordon et al.   NUCLEIC ACIDS RESEARCH

Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex

(2017) Paula Upla et al.   STRUCTURE

Cellular Reorganization during Mitotic Entry

(2017) Lysie Champion et al.   TRENDS IN CELL BIOLOGY

TrypTag.org: A Trypanosome Genome-wide Protein Localisation Resource

(2017) Samuel Dean et al.   TRENDS IN PARASITOLOGY

An evolutionary conserved zinc finger protein is involved inToxoplasma gondiimRNA nuclear export

(2016) Mathieu Gissot et al.   CELLULAR MICROBIOLOGY

Congenital Heart Disease Genetics Uncovers Context-Dependent Organization and Function of Nucleoporins at Cilia

(2016) Florencia del Viso et al.   DEVELOPMENTAL CELL

Nucleoporin-mediated regulation of cell identity genes

(2016) Arkaitz Ibarra et al.   GENES & DEVELOPMENT

SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export

(2016) Michaela Müller-McNicoll et al.   GENES & DEVELOPMENT

Ancient Eukaryotic Origin and Evolutionary Plasticity of Nuclear Lamina

(2016) Ludek Koreny et al.   Genome Biology and Evolution

An NXF1 mRNA with a retained intron is expressed in hippocampal and neocortical neurons and is translated into a protein that functions as an Nxf1 cofactor

(2016) Ying Li et al.   MOLECULAR BIOLOGY OF THE CELL

UAP56 is a conserved crucial component of a divergent mRNA export pathway inToxoplasma gondii

(2016) Mariana Serpeloni et al.   MOLECULAR MICROBIOLOGY

SAC3B, a central component of the mRNA export complex TREX-2, is required for prevention of epigenetic gene silencing inArabidopsis

(2016) Yu Yang et al.   NUCLEIC ACIDS RESEARCH

The Arabidopsis THO/TREX component TEX1 functionally interacts with MOS11 and modulates mRNA export and alternative splicing events

(2016) Brian B. Sørensen et al.   PLANT MOLECULAR BIOLOGY

Molecular architecture of the inner ring scaffold of the human nuclear pore complex

(2016) J. Kosinski et al.   SCIENCE

Visualizing the molecular sociology at the HeLa cell nuclear periphery

(2016) J. Mahamid et al.   SCIENCE

Interactome Mapping Reveals the Evolutionary History of the Nuclear Pore Complex

(2016) Samson O. Obado et al.   PLOS BIOLOGY

Allosteric Regulation in Gating the Central Channel of the Nuclear Pore Complex

(2015) Junseock Koh et al.   CELL

In situ structural analysis of the human nuclear pore complex

(2015) Alexander von Appen et al.   NATURE

Linker Nups connect the nuclear pore complex inner ring with the outer ring and transport channel

(2015) Jessica Fischer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The principal mRNA nuclear export factor NXF1:NXT1 forms a symmetric binding platform that facilitates export of retroviral CTE-RNA

(2015) Shintaro Aibara et al.   NUCLEIC ACIDS RESEARCH

Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface

(2015) Shintaro Aibara et al.   NUCLEIC ACIDS RESEARCH

InsP6-Sensitive Variants of the Gle1 mRNA Export Factor Rescue Growth and Fertility Defects of theipk1Low-Phytic-Acid Mutation in Arabidopsis

(2015) Ho-Seok Lee et al.   PLANT CELL

TheChlamydomonascell cycle

(2015) Frederick R. Cross et al.   PLANT JOURNAL

Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2

(2015) Lyudmila Dimitrova et al.   STRUCTURE

RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1

(2015) Eeva Kaisa Rajakylä et al.   Nature Communications

Linker Nups connect the nuclear pore complex inner ring with the outer ring and transport channel

(2015) Jessica Fischer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Marker gene tethering by nucleoporins affects gene expression in plants

(2015) Sarah Smith et al.   Nucleus

Marker gene tethering by nucleoporins affects gene expression in plants

(2015) Sarah Smith et al.   Nucleus

Structural characterization of the principal mRNA-export factor Mex67–Mtr2 fromChaetomium thermophilum

(2015) Shintaro Aibara et al.   Acta Crystallographica Section F-Structural Biology Communications

Integrative Structure–Function Mapping of the Nucleoporin Nup133 Suggests a Conserved Mechanism for Membrane Anchoring of the Nuclear Pore Complex

(2014) Seung Joong Kim et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural Characterization by Cross-linking Reveals the Detailed Architecture of a Coatomer-related Heptameric Module from the Nuclear Pore Complex

(2014) Yi Shi et al.   MOLECULAR & CELLULAR PROTEOMICS

Nuclear pore complex evolution: a trypanosome Mlp analogue functions in chromosomal segregation but lacks transcriptional barrier activity

(2014) Jennifer M. Holden et al.   MOLECULAR BIOLOGY OF THE CELL

Structural basis for binding the TREX2 complex to nuclear pores, GAL1 localisation and mRNA export

(2014) Divyang Jani et al.   NUCLEIC ACIDS RESEARCH

Characterization of nuclear pore complex components in fission yeastSchizosaccharomyces pombe

(2014) Haruhiko Asakawa et al.   Nucleus

Structural characterization of altered nucleoporin Nup153 expression in human cells by thin-section electron microscopy

(2014) Vincent Duheron et al.   Nucleus

Nucleoporin Nup188 is required for chromosome alignment in mitosis

(2013) Go Itoh et al.   CANCER SCIENCE

Integrated Structural Analysis of the Human Nuclear Pore Complex Scaffold

(2013) Khanh Huy Bui et al.   CELL

A Role for the Nucleoporin Nup170p in Chromatin Structure and Gene Silencing

(2013) David W. Van de Vosse et al.   CELL

Nucleoporin Nup62 maintains centrosome homeostasis

(2013) Chieko Hashizume et al.   CELL CYCLE

An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier

(2013) David K. Breslow et al.   JOURNAL OF CELL BIOLOGY

Interaction of Nup53 with Ndc1 and Nup155 is required for nuclear pore complex assembly

(2013) Nathalie Eisenhardt et al.   JOURNAL OF CELL SCIENCE

The human TREX-2 complex is stably associated with the nuclear pore basket

(2013) D. Umlauf et al.   JOURNAL OF CELL SCIENCE

The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome

(2013) Mario Niepel et al.   MOLECULAR BIOLOGY OF THE CELL

The nuclear mRNA export receptor Mex67-Mtr2 ofTrypanosoma bruceicontains a unique and essential zinc finger motif

(2013) Anna Dostalova et al.   MOLECULAR MICROBIOLOGY

Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines

(2013) A. Ori et al.   Molecular Systems Biology

Arabidopsis DEAD-Box RNA Helicase UAP56 Interacts with Both RNA and DNA as well as with mRNA Export Factors

(2013) Christine Kammel et al.   PLoS One

Protein Interfaces of the Conserved Nup84 Complex from Chaetomium thermophilum Shown by Crosslinking Mass Spectrometry and Electron Microscopy

(2013) Karsten Thierbach et al.   STRUCTURE

Vesicle coats: structure, function, and general principles of assembly

(2013) Marco Faini et al.   TRENDS IN CELL BIOLOGY

A Conserved Role for Human Nup98 in Altering Chromatin Structure and Promoting Epigenetic Transcriptional Memory

(2013) William H. Light et al.   PLOS BIOLOGY

Recruitment of TREX to the Transcription Machinery by Its Direct Binding to the Phospho-CTD of RNA Polymerase II

(2013) Dominik M. Meinel et al.   PLoS Genetics

A single molecule view on Dbp5 and mRNA at the nuclear pore

(2013) Tim Kaminski et al.   Nucleus

A Change in Nuclear Pore Complex Composition Regulates Cell Differentiation

(2012) Maximiliano A. D'Angelo et al.   DEVELOPMENTAL CELL

The Nup153-Nup50 Protein Interface and Its Role in Nuclear Import

(2012) Masaki Makise et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A size-exclusion permeability barrier and nucleoporins characterize a ciliary pore complex that regulates transport into cilia

(2012) Hooi Lynn Kee et al.   NATURE CELL BIOLOGY

Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex

(2012) Andrew M Ellisdon et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export

(2012) Divyang Jani et al.   NUCLEIC ACIDS RESEARCH

TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export

(2012) Nicolas Viphakone et al.   Nature Communications

Dbp5, Gle1-IP6and Nup159

(2012) Andrew W. Folkmann et al.   Nucleus

Comparative genomics of proteins involved in RNA nucleocytoplasmic export

(2011) Mariana Serpeloni et al.   BMC EVOLUTIONARY BIOLOGY

Insight into Structure and Assembly of the Nuclear Pore Complex by Utilizing the Genome of a Eukaryotic Thermophile

(2011) Stefan Amlacher et al.   CELL

Modulation of chromatin position and gene expression by HDAC4 interaction with nucleoporins

(2011) Izhak Kehat et al.   JOURNAL OF CELL BIOLOGY

Localization of retinitis pigmentosa 2 to cilia is regulated by Importin  2

(2011) T. W. Hurd et al.   JOURNAL OF CELL SCIENCE

A Conserved Coatomer-related Complex Containing Sec13 and Seh1 Dynamically Associates With the Vacuole inSaccharomyces cerevisiae

(2011) Svetlana Dokudovskaya et al.   MOLECULAR & CELLULAR PROTEOMICS

An Essential Nuclear Protein in Trypanosomes Is a Component of mRNA Transcription/Export Pathway

(2011) Mariana Serpeloni et al.   PLoS One

Trafficking to the Ciliary Membrane: How to Get Across the Periciliary Diffusion Barrier?

(2010) Maxence V. Nachury et al.   Annual Review of Cell and Developmental Biology

Genome-wide in silico screen for CCCH-type zinc finger proteins of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major

(2010) Susanne Kramer et al.   BMC GENOMICS

Chromatin-Bound Nuclear Pore Components Regulate Gene Expression in Higher Eukaryotes

(2010) Maya Capelson et al.   CELL

Nucleoporins Directly Stimulate Expression of Developmental and Cell-Cycle Genes Inside the Nucleoplasm

(2010) Bernike Kalverda et al.   CELL

Exceptional structural and mechanical flexibility of the nuclear pore complex

(2010) Ivan Liashkovich et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-β2 and RanGTP

(2010) John F. Dishinger et al.   NATURE CELL BIOLOGY

Identification and Characterization of Nuclear Pore Complex Components inArabidopsis thaliana

(2010) Kentaro Tamura et al.   PLANT CELL

Comparative Genomic Evidence for a Complete Nuclear Pore Complex in the Last Eukaryotic Common Ancestor

(2010) Nadja Neumann et al.   PLoS One

Putative Arabidopsis THO/TREX mRNA export complex is involved in transgene and endogenous siRNA biosynthesis

(2010) N. E. Yelina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear export of mRNA

(2010) Murray Stewart   TRENDS IN BIOCHEMICAL SCIENCES

Nuclear Pore Proteins Nup153 and Megator Define Transcriptionally Active Regions in the Drosophila Genome

(2010) Juan M. Vaquerizas et al.   PLoS Genetics

Structural and functional restraints in the evolution of protein families and superfamilies

(2009) Sungsam Gong et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Evidence for a Shared Nuclear Pore Complex Architecture That Is Conserved from the Last Common Eukaryotic Ancestor

(2009) Jeffrey A. DeGrasse et al.   MOLECULAR & CELLULAR PROTEOMICS

The Nup107-160 Nucleoporin Complex Promotes Mitotic Events via Control of the Localization State of the Chromosome Passenger Complex

(2009) Melpomeni Platani et al.   MOLECULAR BIOLOGY OF THE CELL

Sus1, Cdc31, and the Sac3 CID Region Form a Conserved Interaction Platform that Promotes Nuclear Pore Association and mRNA Export

(2009) Divyang Jani et al.   MOLECULAR CELL

Orchestrating nuclear envelope disassembly and reassembly during mitosis

(2009) Stephan Güttinger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural and functional constraints in the evolution of protein families

(2009) Catherine L. Worth et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of deadenylation in the degradation of unstable mRNAs in trypanosomes

(2009) Angela Schwede et al.   NUCLEIC ACIDS RESEARCH

TriTrypDB: a functional genomic resource for the Trypanosomatidae

(2009) Martin Aslett et al.   NUCLEIC ACIDS RESEARCH

Dual functions ofNicotiana benthamianaRae1 in interphase and mitosis

(2009) Jae-Yong Lee et al.   PLANT JOURNAL

Arabidopsis homolog of the yeast TREX-2 mRNA export complex: components and anchoring nucleoporin

(2009) Qing Lu et al.   PLANT JOURNAL

Protein co-evolution, co-adaptation and interactions

(2008) Florencio Pazos et al.   EMBO JOURNAL

Systematic kinetic analysis of mitotic dis- and reassembly of the nuclear pore in living cells

(2008) Elisa Dultz et al.   JOURNAL OF CELL BIOLOGY

Centrin 2 Localizes to the Vertebrate Nuclear Pore and Plays a Role in mRNA and Protein Export

(2008) K. K. Resendes et al.   MOLECULAR AND CELLULAR BIOLOGY

Capture of AT-rich Chromatin by ELYS Recruits POM121 and NDC1 to Initiate Nuclear Pore Assembly

(2008) Beth A. Rasala et al.   MOLECULAR BIOLOGY OF THE CELL

Artificial nanopores that mimic the transport selectivity of the nuclear pore complex

(2008) Tijana Jovanovic-Talisman et al.   NATURE