Workshop on RanBP2/Nup358 and acute necrotizing encephalopathy

Endoplasmic reticulum–mitochondria signaling in neurons and neurodegenerative diseases

(2022) Andrea Markovinovic et al.   JOURNAL OF CELL SCIENCE

The different autophagy degradation pathways and neurodegeneration

(2022) Angeleen Fleming et al.   NEURON

Clinical Manifestations and Pathogenesis of Acute Necrotizing Encephalopathy: The Interface Between Systemic Infection and Neurologic Injury

(2022) Priya Shukla et al.   Frontiers in Neurology

Roles of Nucleoporin RanBP2/Nup358 in Acute Necrotizing Encephalopathy Type 1 (ANE1) and Viral Infection

(2022) Jing Jiang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Coil-to-α-helix transition at the Nup358-BicD2 interface activates BicD2 for dynein recruitment

(2022) James M Gibson et al.   eLife

Cytokines in CAR T Cell–Associated Neurotoxicity

(2021) Juliane Gust et al.   Frontiers in Immunology

RanBP2/Nup358 enhances miRNA activity by sumoylating Argonautes

(2021) Qingtang Shen et al.   PLoS Genetics

Acute necrotizing encephalopathy-linked mutations in Nup358 impair interaction of Nup358 with TNRC6/GW182 and miRNA function

(2021) Prachi Deshmukh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Crosstalk between nucleocytoplasmic trafficking and the innate immune response to viral infection

(2021) Qingtang Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein

(2021) Kris White et al.   JOURNAL OF MEDICINAL CHEMISTRY

SUMO paralogue–specific functions revealed through systematic analysis of human knockout cell lines and gene expression data

(2021) Danielle Bouchard et al.   MOLECULAR BIOLOGY OF THE CELL

Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS

(2021) Alyssa N. Coyne et al.   Science Translational Medicine

Phosphorylation-dependent mitotic SUMOylation drives nuclear envelope–chromatin interactions

(2021) Christopher Ptak et al.   JOURNAL OF CELL BIOLOGY

Association of RanGAP to nuclear pore complex component, RanBP2/Nup358, is required for pupal development in Drosophila

(2021) Shane Chen et al.   Cell Reports

RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

(2020) Jordina Guillén-Boixet et al.   CELL

A first case of meningitis/encephalitis associated with SARS-Coronavirus-2

(2020) Takeshi Moriguchi et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features

(2020) Neo Poyiadji et al.   RADIOLOGY

Chemical intervention of influenza virus mRNA nuclear export

(2020) Matthew Esparza et al.   PLoS Pathogens

CHMPions of repair: Emerging perspectives on sensing and repairing the nuclear envelope barrier

(2020) C. Patrick Lusk et al.   CURRENT OPINION IN CELL BIOLOGY

The Nuclear SUMO-Targeted Ubiquitin Quality Control Network Regulates the Dynamics of Cytoplasmic Stress Granules

(2020) Jan Keiten-Schmitz et al.   MOLECULAR CELL

Acute necrotizing encephalopathy with SARS-CoV-2 RNA confirmed in cerebrospinal fluid

(2020) Johan Virhammar et al.   NEUROLOGY

G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD

(2020) Alyssa N. Coyne et al.   NEURON

Vpu modulates DNA repair to suppress innate sensing and hyper-integration of HIV-1

(2020) Meta Volcic et al.   Nature Microbiology

CoRNeA: A Pipeline to Decrypt the Inter-Protein Interfaces from Amino Acid Sequence Information

(2020) Kriti Chopra et al.   Biomolecules

Guidelines for the diagnosis and treatment of acute encephalopathy in childhood

(2020) Masashi Mizuguchi et al.   BRAIN & DEVELOPMENT

Molecular and structural analysis of central transport channel in complex with Nup93 of Nuclear Pore Complex

(2020) Parshuram J. Sonawane et al.   PROTEIN SCIENCE

Spatiotemporal Proteomic Analysis of Stress Granule Disassembly Using APEX Reveals Regulation by SUMOylation and Links to ALS Pathogenesis

(2020) Hagai Marmor-Kollet et al.   MOLECULAR CELL

cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing

(2020) Carolina Uggenti et al.   NATURE GENETICS

NUP214 deficiency causes severe encephalopathy and microcephaly in humans

(2019) Hanan E. Shamseldin et al.   HUMAN GENETICS

Favorable outcomes with early interleukin-6 receptor blockade in severe acute necrotizing encephalopathy of childhood

(2019) Janine Cynthia Koh et al.   PEDIATRIC NEUROLOGY

Pathogenic Variants in NUP214 Cause “Plugged” Nuclear Pore Channels and Acute Febrile Encephalopathy

(2019) Boris Fichtman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Thermolabile polymorphism of carnitine palmitoyltransferase 2: A genetic risk factor of overall acute encephalopathy

(2019) Akiko Shibata et al.   BRAIN & DEVELOPMENT

ORKAMBI-Mediated Rescue of Mucociliary Clearance in Cystic Fibrosis Primary Respiratory Cultures Is Enhanced by Arginine Uptake, Arginase Inhibition, and Promotion of Nitric Oxide Signaling to the Cystic Fibrosis Transmembrane Conductance Regulator Channel

(2019) Yu-Sheng Wu et al.   MOLECULAR PHARMACOLOGY

Carbon nanotubes as molecular transporters to study a new mechanism for molecular entry into the cell nucleus using actin polymerization force

(2019) Shaghayegh Sadr Karimi et al.   PLoS One

Adapter Proteins for Opposing Motors Interact Simultaneously with Nuclear Pore Protein Nup358

(2019) Heying Cui et al.   BIOCHEMISTRY

Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis

(2019) Bernhard Hampoelz et al.   CELL

Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating

(2019) Juliette Fernandez et al.   Nature Microbiology

Functional rescue of c.3846G>A (W1282X) in patient-derived nasal cultures achieved by inhibition of nonsense mediated decay and protein modulators with complementary mechanisms of action

(2019) Onofrio Laselva et al.   Journal of Cystic Fibrosis

P-Bodies: Composition, Properties, and Functions

(2018) Yang Luo et al.   BIOCHEMISTRY

Stress Granule Assembly Disrupts Nucleocytoplasmic Transport

(2018) Ke Zhang et al.   CELL

Transducing Airway Basal Cells with a Helper-Dependent Adenoviral Vector for Lung Gene Therapy

(2018) Huibi Cao et al.   HUMAN GENE THERAPY

Endoplasmic Reticulum–Mitochondrial Contactology: Structure and Signaling Functions

(2018) György Csordás et al.   TRENDS IN CELL BIOLOGY

Species-specific vulnerability of RanBP2 shaped the evolution of SIV as it transmitted in African apes

(2018) Nicholas R. Meyerson et al.   PLoS Pathogens

Acute necrotizing encephalopathy and a carnitine palmitoyltransferase 2 variant in an adult

(2018) Yuya Kobayashi et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Cap-binding protein 4EHP effects translation silencing by microRNAs

(2017) Clément Chapat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection

(2017) Adarsh Dharan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin α isoforms

(2017) Wei Wu et al.   Scientific Reports

Single particle imaging of mRNAs crossing the nuclear pore: Surfing on the edge

(2016) Alexander F. Palazzo et al.   BIOESSAYS

Serial outcomes in acute necrotising encephalopathy of childhood: A medium and long term study

(2016) Hwee Ying Lim et al.   BRAIN & DEVELOPMENT

Pre-assembled Nuclear Pores Insert into the Nuclear Envelope during Early Development

(2016) Bernhard Hampoelz et al.   CELL

Chm7 and Heh1 collaborate to link nuclear pore complex quality control with nuclear envelope sealing

(2016) Brant M Webster et al.   EMBO JOURNAL

Nup358 binds to AGO proteins through its SUMO‐interacting motifs and promotes the association of target mRNA with miRISC

(2016) Manas Ranjan Sahoo et al.   EMBO REPORTS

Familial acute necrotizing encephalopathy withoutRANBP2mutation: Poor outcome

(2016) Naoko Nishimura et al.   PEDIATRICS INTERNATIONAL

Endogenous TRIM5α Function Is Regulated by SUMOylation and Nuclear Sequestration for Efficient Innate Sensing in Dendritic Cells

(2016) Débora M. Portilho et al.   Cell Reports

KIF5B and Nup358 Cooperatively Mediate the Nuclear Import of HIV-1 during Infection

(2016) Adarsh Dharan et al.   PLoS Pathogens

Targeting the Cyclophilin Domain of Ran-binding Protein 2 (Ranbp2) with Novel Small Molecules to Control the Proteostasis of STAT3, hnRNPA2B1 and M-Opsin

(2015) Kyoung-in Cho et al.   ACS Chemical Neuroscience

The C9orf72 repeat expansion disrupts nucleocytoplasmic transport

(2015) Ke Zhang et al.   NATURE

Nuclear architecture dictates HIV-1 integration site selection

(2015) Bruna Marini et al.   NATURE

Nuclear entry of DNA viruses

(2015) Nikta Fay et al.   Frontiers in Microbiology

RanBP2/Nup358 Potentiates the Translation of a Subset of mRNAs Encoding Secretory Proteins

(2014) Kohila Mahadevan et al.   PLOS BIOLOGY

Electron Tomography and Simulation of Baculovirus Actin Comet Tails Support a Tethered Filament Model of Pathogen Propulsion

(2014) Jan Mueller et al.   PLOS BIOLOGY

Dynein Recruitment to Nuclear Pores Activates Apical Nuclear Migration and Mitotic Entry in Brain Progenitor Cells

(2013) Daniel Jun-Kit Hu et al.   CELL

Neurological Manifestations of Influenza Infection in Children and Adults: Results of a National British Surveillance Study

(2013) Anu Goenka et al.   CLINICAL INFECTIOUS DISEASES

Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport

(2013) Hicham Mahboubi et al.   PLoS One

Parvoviruses Cause Nuclear Envelope Breakdown by Activating Key Enzymes of Mitosis

(2013) Manvi Porwal et al.   PLoS Pathogens

Crystal Structure of the N-Terminal Domain of Nup358/RanBP2

(2012) Susanne A. Kassube et al.   JOURNAL OF MOLECULAR BIOLOGY

Endoplasmic reticulum–mitochondria contacts: function of the junction

(2012) Ashley A. Rowland et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration

(2012) Francesca Di Nunzio et al.   PLoS One

Nuclear Envelope Disruption Involving Host Caspases Plays a Role in the Parvovirus Replication Cycle

(2011) S. Cohen et al.   JOURNAL OF VIROLOGY

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress

(2010) K.-i. Cho et al.   Disease Models & Mechanisms

Actin-based motility drives baculovirus transit to the nucleus and cell surface

(2010) Taro Ohkawa et al.   JOURNAL OF CELL BIOLOGY

Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study

(2010) Julia Granerod et al.   LANCET INFECTIOUS DISEASES

Bicaudal D2, Dynein, and Kinesin-1 Associate with Nuclear Pore Complexes and Regulate Centrosome and Nuclear Positioning during Mitotic Entry

(2010) Daniël Splinter et al.   PLOS BIOLOGY

Nucleoporin 153 Arrests the Nuclear Import of Hepatitis B Virus Capsids in the Nuclear Basket

(2010) André Schmitz et al.   PLoS Pathogens

Infection-Triggered Familial or Recurrent Cases of Acute Necrotizing Encephalopathy Caused by Mutations in a Component of the Nuclear Pore, RANBP2

(2009) Derek E. Neilson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The role of nuclear pores in gene regulation, development and disease

(2009) Maya Capelson et al.   EMBO REPORTS

Nup358 interacts with APC and plays a role in cell polarization

(2009) P. Murawala et al.   JOURNAL OF CELL SCIENCE

Outcome of acute necrotizing encephalopathy in relation to treatment with corticosteroids and gammaglobulin

(2008) Akihisa Okumura et al.   BRAIN & DEVELOPMENT

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons

(2008) K-in Cho et al.   CELL DEATH AND DIFFERENTIATION

A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

(2008) Takbum Ohn et al.   NATURE CELL BIOLOGY