Therapeutic Phage Monitoring: A Review

Gram negative bacterial infection causes aggravated innate immune response in sepsis: Studies from clinical study and cellular models

(2023) Chujun Duan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pharmacokinetics/pharmacodynamics of phage therapy: a major hurdle to clinical translation

(2023) Sue C. Nang et al.   CLINICAL MICROBIOLOGY AND INFECTION

The oral microbiome in the pathophysiology of cardiovascular disease

(2023) Andrea Tonelli et al.   Nature Reviews Cardiology

The Bidirectional Gut–Lung Axis in Chronic Obstructive Pulmonary Disease

(2023) Lei Wang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

LInezolid Monitoring to MInimise Toxicity (LIMMIT1): A multicentre retrospective review of patients receiving linezolid therapy and the impact of therapeutic drug monitoring

(2023) Cindy Lau et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Gut microbiota in colorectal cancer development and therapy

(2023) Chi Chun Wong et al.   Nature Reviews Clinical Oncology

Microbiome and Vulvovaginitis

(2023) Anna Maya Powell et al.   OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA

Phage diversity in cell-free DNA identifies bacterial pathogens in human sepsis cases

(2023) Naomi L. Haddock et al.   Nature Microbiology

Targeted suppression of human IBD-associated gut microbiota commensals by phage consortia for treatment of intestinal inflammation

(2022) Sara Federici et al.   CELL

Phage Therapy of Mycobacterium Infections: Compassionate-use of Phages in Twenty Patients with Drug-Resistant Mycobacterial Disease

(2022) Rebekah M. Dedrick et al.   CLINICAL INFECTIOUS DISEASES

Evolutionary Dynamics between Phages and Bacteria as a Possible Approach for Designing Effective Phage Therapies against Antibiotic-Resistant Bacteria

(2022) Mahadi Hasan et al.   Antibiotics-Basel

Determination of phage susceptibility as a clinical diagnostic tool: A routine perspective

(2022) Valéry Daubie et al.   Frontiers in Cellular and Infection Microbiology

Do Anti-Phage Antibodies Persist after Phage Therapy? A Preliminary Report

(2022) Marzanna Łusiak-Szelachowska et al.   Antibiotics-Basel

The Safety and Efficacy of Phage Therapy: A Systematic Review of Clinical and Safety Trials

(2022) Helen J. Stacey et al.   Antibiotics-Basel

Standardised treatment and monitoring protocol to assess safety and tolerability of bacteriophage therapy for adult and paediatric patients (STAMP study): protocol for an open-label, single-arm trial

(2022) Ameneh Khatami et al.   BMJ Open

Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials

(2021) Fernando Gordillo Altamirano et al.   Nature Microbiology

Aztreonam Lysine Increases the Activity of Phages E79 and phiKZ against Pseudomonas aeruginosa PA01

(2021) Carly M. Davis et al.   Microorganisms

Phage-specific antibodies

(2021) Katarzyna Gembara et al.   CURRENT OPINION IN BIOTECHNOLOGY

Phage Biobank: Present Challenges and Future Perspectives

(2021) Ruby CY Lin et al.   CURRENT OPINION IN BIOTECHNOLOGY

Drug dosing considerations in continuous renal replacement therapy

(2021) Soo Min Jang et al.   SEMINARS IN DIALYSIS

Assessment of the microbiome during bacteriophage therapy in combination with systemic antibiotics to treat a case of staphylococcal device infection

(2021) Andre Mu et al.   Microbiome

Bacterial lysis, autophagy and innate immune responses during adjunctive phage therapy in a child

(2021) Ameneh Khatami et al.   EMBO Molecular Medicine

Potent antibody-mediated neutralization limits bacteriophage treatment of a pulmonary Mycobacterium abscessus infection

(2021) Rebekah M. Dedrick et al.   NATURE MEDICINE

A Case of In Situ Phage Therapy against Staphylococcus aureus in a Bone Allograft Polymicrobial Biofilm Infection: Outcomes and Phage-Antibiotic Interactions

(2021) Brieuc Van Nieuwenhuyse et al.   Viruses-Basel

The Safety and Toxicity of Phage Therapy: A Review of Animal and Clinical Studies

(2021) Dan Liu et al.   Viruses-Basel

Clinical Phage Microbiology: a suggested framework and recommendations for the in-vitro matching steps of phage therapy

(2021) Daniel Gelman et al.   Lancet Microbe

Oral Is the New IV. Challenging Decades of Blood and Bone Infection Dogma: A Systematic Review

(2021) Noah Wald-Dickler et al.   AMERICAN JOURNAL OF MEDICINE

The effect of therapeutic drug monitoring of beta-lactam and fluoroquinolones on clinical outcome in critically ill patients: the DOLPHIN trial protocol of a multi-centre randomised controlled trial

(2020) A. Abdulla et al.   BMC INFECTIOUS DISEASES

Safety of bacteriophage therapy in severe Staphylococcus aureus infection

(2020) Aleksandra Petrovic Fabijan et al.   Nature Microbiology

Interaction between microbiota and immunity in health and disease

(2020) Danping Zheng et al.   CELL RESEARCH

Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#

(2020) Mohd H. Abdul-Aziz et al.   INTENSIVE CARE MEDICINE

Kinetics of plasma HIV rebound in the era of modern antiretroviral therapy

(2020) Michael C Sneller et al.   JOURNAL OF INFECTIOUS DISEASES

Revealing COVID-19 transmission in Australia by SARS-CoV-2 genome sequencing and agent-based modeling

(2020) Rebecca J. Rockett et al.   NATURE MEDICINE

Clinical Pathogen Genomics

(2020) Andrew Cameron et al.   CLINICS IN LABORATORY MEDICINE

A blood transcriptome-based analysis of disease progression, immune regulation, and symptoms in coronavirus-infected patients

(2020) Anguraj Sadanandam et al.   Cell Death Discovery

Delivery of CRISPR-Cas systems using phage-based vectors

(2020) Clément Fage et al.   CURRENT OPINION IN BIOTECHNOLOGY

Phages to shape the gut microbiota?

(2020) Sofia Dahlman et al.   CURRENT OPINION IN BIOTECHNOLOGY

Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review

(2019) Krystyna Dąbrowska   MEDICINAL RESEARCH REVIEWS

Understanding and overcoming the pitfalls and biases of next-generation sequencing (NGS) methods for use in the routine clinical microbiological diagnostic laboratory

(2019) Stefan A. Boers et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Bacteriophage PEV20 and Ciprofloxacin Combination Treatment Enhances Removal of Pseudomonas aeruginosa Biofilm Isolated from Cystic Fibrosis and Wound Patients

(2019) Rachel Yoon Kyung Chang et al.   AAPS Journal

Current State of Compassionate Phage Therapy

(2019) McCallin et al.   Viruses-Basel

Antibiotics versus biofilm: an emerging battleground in microbial communities

(2019) Divakar Sharma et al.   Antimicrobial Resistance and Infection Control

Dynamic Modulation of the Gut Microbiota and Metabolome by Bacteriophages in a Mouse Model

(2019) Bryan B. Hsu et al.   Cell Host & Microbe

Safety and Tolerability of Bacteriophage Therapy for Chronic Rhinosinusitis Due to Staphylococcus aureus

(2019) Mian Li Ooi et al.   JAMA Otolaryngology-Head & Neck Surgery

Bacteriophage Therapy of Ventilator-associated Pneumonia and Empyema caused by Pseudomonas aeruginosa

(2019) Susan Maddocks et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Treatment of MDR-TB using therapeutic drug monitoring: first experiences with sub-300 mg linezolid dosages using in-house made capsules

(2019) Mathieu S. Bolhuis et al.   EUROPEAN RESPIRATORY JOURNAL

Cost-effectiveness of precision medicine: a scoping review

(2019) Miriam Kasztura et al.   International Journal of Public Health

Pharmacologically Aware Phage Therapy: Pharmacodynamic and Pharmacokinetic Obstacles to Phage Antibacterial Action in Animal and Human Bodies

(2019) Krystyna Dąbrowska et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Induction of Phage-Specific Antibodies by Two Therapeutic Staphylococcal Bacteriophages Administered per os

(2019) Joanna Majewska et al.   Frontiers in Immunology

Pathogen Genomics in Public Health

(2019) Gregory L. Armstrong et al.   NEW ENGLAND JOURNAL OF MEDICINE

Augmented Renal Clearance in Critically Ill Patients: A Systematic Review

(2018) Idoia Bilbao-Meseguer et al.   CLINICAL PHARMACOKINETICS

Validation of AclarusDx™, a Blood-Based Transcriptomic Signature for the Diagnosis of Alzheimer's Disease

(2018) Pascale Fehlbaum-Beurdeley et al.   JOURNAL OF ALZHEIMERS DISEASE

Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial

(2018) Patrick Jault et al.   LANCET INFECTIOUS DISEASES

Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System

(2018) Jonas Van Belleghem et al.   Viruses-Basel

Use of C-reactive protein to tailor antibiotic use: a systematic review and meta-analysis

(2018) Dara Petel et al.   BMJ Open

What is precision medicine?

(2017) Inke R. König et al.   EUROPEAN RESPIRATORY JOURNAL

Phages and immunomodulation

(2017) Andrzej Górski et al.   Future Microbiology

Persistent bacterial infections and persister cells

(2017) Robert A. Fisher et al.   NATURE REVIEWS MICROBIOLOGY

Refractory Pseudomonas Bacteremia in a 2-Year-Old Sterilized by Bacteriophage Therapy

(2017) C. Duplessis et al.   Journal of the Pediatric Infectious Diseases Society

Bacteriophages and phage-inspired nanocarriers for targeted delivery of therapeutic cargos

(2016) Mahdi Karimi et al.   ADVANCED DRUG DELIVERY REVIEWS

Temporal Stability of the Human Skin Microbiome

(2016) Julia Oh et al.   CELL

The negative impact of antibiotic resistance

(2016) N.D. Friedman et al.   CLINICAL MICROBIOLOGY AND INFECTION

Bacteriophages to reduce gut carriage of antibiotic resistant uropathogens with low impact on microbiota composition

(2016) Matthieu Galtier et al.   ENVIRONMENTAL MICROBIOLOGY

Filamentous Bacteriophage Produced by Pseudomonas aeruginosa Alters the Inflammatory Response and Promotes Noninvasive Infection In Vivo

(2016) Patrick R. Secor et al.   INFECTION AND IMMUNITY

Bacteriophage therapy: a regulatory perspective

(2016) Eric Pelfrene et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Towards precision medicine

(2016) Euan A. Ashley   NATURE REVIEWS GENETICS

T4 Phage Tail Adhesin Gp12 Counteracts LPS-Induced Inflammation In Vivo

(2016) Paulina Miernikiewicz et al.   Frontiers in Microbiology

Phage Therapy: Combating Infections with Potential for Evolving from Merely a Treatment for Complications to Targeting Diseases

(2016) Andrzej Górski et al.   Frontiers in Microbiology

Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh

(2016) Shafiqul Alam Sarker et al.   EBioMedicine

Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa

(2016) Benjamin K. Chan et al.   Scientific Reports

Antipseudomonal Bacteriophage Reduces Infective Burden and Inflammatory Response in Murine Lung

(2015) Rishi Pabary et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Understanding PK/PD

(2015) Jason A. Roberts et al.   INTENSIVE CARE MEDICINE

Assessment of immune status using blood transcriptomics and potential implications for global health

(2015) Damien Chaussabel   SEMINARS IN IMMUNOLOGY

Making the Leap from Research Laboratory to Clinic: Challenges and Opportunities for Next-Generation Sequencing in Infectious Disease Diagnostics

(2015) Brittany Goldberg et al.   mBio

The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease

(2015) Robert P. Dickson et al.   PLoS Pathogens

Evaluation of the Efficacy of a Bacteriophage in the Treatment of Pneumonia Induced by Multidrug ResistanceKlebsiella pneumoniaein Mice

(2015) Fang Cao et al.   Biomed Research International

How do we use therapeutic drug monitoring to improve outcomes from severe infections in critically ill patients?

(2014) Gloria Wong et al.   BMC INFECTIOUS DISEASES

Observation of inflammatory responses in mice orally fed with bacteriophage T7

(2014) K. Park et al.   JOURNAL OF APPLIED MICROBIOLOGY

Cost-Effectiveness of Using Pharmacogenetic Information in Warfarin Dosing for Patients With Nonvalvular Atrial Fibrillation

(2013) Mark H. Eckman   ANNALS OF INTERNAL MEDICINE

In VivoEffects of Cefazolin, Daptomycin, and Nafcillin in Experimental Endocarditis with a Methicillin-Susceptible Staphylococcus aureus Strain Showing an Inoculum Effect against Cefazolin

(2013) Esteban C. Nannini et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Virologic Suppression Measured by a Cytomegalovirus (CMV) DNA Test Calibrated to the World Health Organization International Standard Is Predictive of CMV Disease Resolution in Transplant Recipients

(2013) Raymund R. Razonable et al.   CLINICAL INFECTIOUS DISEASES

Blood RNA biomarker panel detects both left- and right-sided colorectal neoplasms: a case-control study

(2013) Samuel Chao et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Phage therapy of Cronobacter-induced urinary tract infection in mice

(2013) Lubomira Tothova et al.   MEDICAL SCIENCE MONITOR

Understanding Bacteriophage Specificity in Natural Microbial Communities

(2013) Britt Koskella et al.   Viruses-Basel

The role of pharmacokinetics/pharmacodynamics in setting clinical MIC breakpoints: the EUCAST approach

(2011) J.W. Mouton et al.   CLINICAL MICROBIOLOGY AND INFECTION

The human gut virome: Inter-individual variation and dynamic response to diet

(2011) S. Minot et al.   GENOME RESEARCH

Evidence of a robust resident bacteriophage population revealed through analysis of the human salivary virome

(2011) David T Pride et al.   ISME Journal

The antibiotics market

(2010) Bashar Hamad   NATURE REVIEWS DRUG DISCOVERY

Structure and assembly of bacteriophage T4 head

(2010) Venigalla B Rao et al.   Virology Journal

A retrospective analysis of changes in inflammatory markers in patients treated with bacterial viruses

(2009) Ryszard Międzybrodzki et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Antimicrobial Susceptibility Testing: A Review of General Principles and Contemporary Practices

(2009) James H. Jorgensen et al.   CLINICAL INFECTIOUS DISEASES

Overview of Therapeutic Drug Monitoring

(2009) Ju-Seop Kang et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Early Switch to Oral Treatment in Patients with Moderate to Severe Community-Acquired Pneumonia

(2008) Zoe Athanassa et al.   DRUGS

How the study of children with rheumatic diseases identified interferon-α and interleukin-1 as novel therapeutic targets

(2008) Virginia Pascual et al.   IMMUNOLOGICAL REVIEWS

Bacteriophage preparation inhibition of reactive oxygen species generation by endotoxin-stimulated polymorphonuclear leukocytes

(2007) Ryszard Miedzybrodzki et al.   VIRUS RESEARCH