Evolutionary Dynamics between Phages and Bacteria as a Possible Approach for Designing Effective Phage Therapies against Antibiotic-Resistant Bacteria

Outer Membrane Vesicles (OMVs) of Pseudomonas aeruginosa Provide Passive Resistance but Not Sensitization to LPS-Specific Phages

(2022) Daria Augustyniak et al.   Viruses-Basel

A Filamentous Bacteriophage Protein Inhibits Type IV Pili To Prevent Superinfection of Pseudomonas aeruginosa

(2022) Amelia K. Schmidt et al.   mBio

Structure of Escherichia coli O157:H7 bacteriophage CBA120 tailspike protein 4 baseplate anchor and tailspike assembly domains (TSP4-N)

(2022) Kinlin L. Chao et al.   Scientific Reports

Parallel evolution of Pseudomonas aeruginosa phage resistance and virulence loss in response to phage treatment in vivo and in vitro

(2022) Meaghan Castledine et al.   eLife

Characterization of phage resistance and phages capable of intestinal decolonization of carbapenem-resistant Klebsiella pneumoniae in mice

(2022) Qingqing Fang et al.   Communications Biology

Toxin-Antitoxin Systems as Phage Defense Elements

(2022) Michele LeRoux et al.   Annual Review of Microbiology

Rapid Decline of Ceftazidime Resistance in Antibiotic-Free and Sublethal Environments Is Contingent on Genetic Background

(2022) Sara Hernando-Amado et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genomic evolution of antibiotic resistance is contingent on genetic background following a long-term experiment with Escherichia coli

(2021) Kyle J. Card et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacteriophage-resistant Acinetobacter baumannii are resensitized to antimicrobials

(2021) Fernando Gordillo Altamirano et al.   Nature Microbiology

Microbial Arsenal of Antiviral Defenses – Part I

(2021) Artem B. Isaev et al.   BIOCHEMISTRY-MOSCOW

A snapshot of the λ T4rII exclusion (Rex) phenotype in Escherichia coli

(2021) Shirley Wong et al.   CURRENT GENETICS

The evolutionary trade‐offs in phage‐resistant Klebsiella pneumoniae entail cross‐phage sensitization and loss of multidrug resistance

(2021) Grazyna Majkowska‐Skrobek et al.   ENVIRONMENTAL MICROBIOLOGY

Antiviral Resistance and Phage Counter Adaptation to Antibiotic-Resistant Extraintestinal Pathogenic Escherichia coli

(2021) Keiko C. Salazar et al.   mBio

Long-term persistence of crAss-like phage crAss001 is associated with phase variation in Bacteroides intestinalis

(2021) Andrey N. Shkoporov et al.   BMC BIOLOGY

Genome-driven elucidation of phage-host interplay and impact of phage resistance evolution on bacterial fitness

(2021) Pawel Markwitz et al.   ISME Journal

Sustained coevolution of phage Lambda and Escherichia coli involves inner- as well as outer-membrane defences and counter-defences

(2021) Alita R. Burmeister et al.   MICROBIOLOGY-SGM

The Antibiotic Efflux Protein TolC Is a Highly Evolvable Target under Colicin E1 or TLS Phage Selection

(2021) Yusuf Talha Tamer et al.   MOLECULAR BIOLOGY AND EVOLUTION

Structure-based functional mechanisms and biotechnology applications of anti-CRISPR proteins

(2021) Ning Jia et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bacteriophage T4 Escapes CRISPR Attack by Minihomology Recombination and Repair

(2021) Xiaorong Wu et al.   mBio

Campylobacter phages use hypermutable polyG tracts to create phenotypic diversity and evade bacterial resistance

(2021) Martine C. Holst Sørensen et al.   Cell Reports

Evolution of Bacterial Cross-Resistance to Lytic Phages and Albicidin Antibiotic

(2021) Kaitlyn E. Kortright et al.   Frontiers in Microbiology

Selection for Phage Resistance Reduces Virulence of Shigella flexneri

(2021) Kaitlyn E. Kortright et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Survival Comes at a Cost: A Coevolution of Phage and Its Host Leads to Phage Resistance and Antibiotic Sensitivity of Pseudomonas aeruginosa Multidrug Resistant Strains

(2021) Sarshad Koderi Valappil et al.   Frontiers in Microbiology

Prophage integration into CRISPR loci enables evasion of antiviral immunity in Streptococcus pyogenes

(2021) Andrew Varble et al.   Nature Microbiology

Novel Phage-Derived Depolymerase with Activity against Proteus mirabilis Biofilms

(2021) Cormac J. Rice et al.   Microorganisms

Fitness trade-offs resulting from bacteriophage resistance potentiate synergistic antibacterial strategies

(2020) Mihnea R. Mangalea et al.   INFECTION AND IMMUNITY

The arms race between bacteria and their phage foes

(2020) Hannah G. Hampton et al.   NATURE

Phage Resistance in Multidrug-Resistant Klebsiella pneumoniae ST258 Evolves via Diverse Mutations That Culminate in Impaired Adsorption

(2020) Shayla Hesse et al.   mBio

Pleiotropy complicates a trade-off between phage resistance and antibiotic resistance

(2020) Alita R. Burmeister et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A phage-encoded anti-CRISPR enables complete evasion of type VI-A CRISPR-Cas immunity

(2020) Alexander J. Meeske et al.   SCIENCE

A Frameshift Mutation in wcaJ Associated with Phage Resistance in Klebsiella pneumoniae

(2020) Demeng Tan et al.   Microorganisms

The Role of Bacterial Membrane Vesicles in the Dissemination of Antibiotic Resistance and as Promising Carriers for Therapeutic Agent Delivery

(2020) Md Jalal Uddin et al.   Microorganisms

High-throughput discovery of phage receptors using transposon insertion sequencing of bacteria

(2020) Kaitlyn E. Kortright et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Primary Physiological Role of Toxin/Antitoxin Systems Is Phage Inhibition

(2020) Sooyeon Song et al.   Frontiers in Microbiology

Abortive Infection: Bacterial Suicide as an Antiviral Immune Strategy

(2020) Anna Lopatina et al.   Annual Review of Virology

Rapid and robust evolution of collateral sensitivity in Pseudomonas aeruginosa antibiotic-resistant mutants

(2020) Sara Hernando-Amado et al.   Science Advances

Phage steering of antibiotic-resistance evolution in the bacterial pathogen, Pseudomonas aeruginosa

(2020) James Gurney et al.   Evolution Medicine and Public Health

Phages for Biofilm Removal

(2020) Celia Ferriol-González et al.   Antibiotics-Basel

Phage Therapy in the Resistance Era: Where Do We Stand and Where Are We Going?

(2020) Tiffany Luong et al.   CLINICAL THERAPEUTICS

Trading-off and trading-up in the world of bacteria–phage evolution

(2020) Alita R. Burmeister et al.   CURRENT BIOLOGY

Genomic analysis reveals high virulence and antibiotic resistance amongst phage susceptible Acinetobacter baumannii

(2020) Udomluk Leungtongkam et al.   Scientific Reports

Structural basis of superinfection exclusion by bacteriophage T4 Spackle

(2020) Ke Shi et al.   Communications Biology

Beyond antibacterials – exploring bacteriophages as antivirulence agents

(2020) Yang Shen et al.   CURRENT OPINION IN BIOTECHNOLOGY

Identification and characterization of capsule depolymerase Dpo48 from Acinetobacter baumannii phage IME200

(2019) Yannan Liu et al.   PeerJ

Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains

(2019) Olivier Cunrath et al.   EBioMedicine

Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria

(2019) Kaitlyn E. Kortright et al.   Cell Host & Microbe

(Ph)ighting Phages: How Bacteria Resist Their Parasites

(2019) Jakob T. Rostøl et al.   Cell Host & Microbe

Assessment of the alteration in phage adsorption rates of antibiotic-resistant Salmonella typhimurium

(2019) Md Jalal Uddin et al.   ARCHIVES OF MICROBIOLOGY

Bacteriophage Resistance Alters Antibiotic-Mediated Intestinal Expansion of Enterococci

(2019) Anushila Chatterjee et al.   INFECTION AND IMMUNITY

Three Capsular Polysaccharide Synthesis-Related Glucosyltransferases, GT-1, GT-2 and WcaJ, Are Associated With Virulence and Phage Sensitivity of Klebsiella pneumoniae

(2019) Ruopeng Cai et al.   Frontiers in Microbiology

Anti-CRISPR-Associated Proteins Are Crucial Repressors of Anti-CRISPR Transcription

(2019) Sabrina Y. Stanley et al.   CELL

Bacterial biodiversity drives the evolution of CRISPR-based phage resistance

(2019) Ellinor O. Alseth et al.   NATURE

The interaction of phages and bacteria: the co-evolutionary arms race

(2019) Fatemeh Safari et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

How bacteria control the CRISPR-Cas arsenal

(2018) Lina M Leon et al.   CURRENT OPINION IN MICROBIOLOGY

Rapid evolution of generalized resistance mechanisms can constrain the efficacy of phage-antibiotic treatments

(2018) Claire E. Moulton-Brown et al.   Evolutionary Applications

Phages & antibiotic resistance: are the most abundant entities on earth ready for a comeback?

(2018) Colin Hill et al.   Future Microbiology

Three-dimensional structures of bacteriophage neck subunits are shared in Podoviridae , Siphoviridae and Myoviridae

(2018) Takuma Iwasaki et al.   GENES TO CELLS

Genomic and Biochemical Characterization of Acinetobacter Podophage Petty Reveals a Novel Lysis Mechanism and Tail-Associated Depolymerase Activity

(2018) A. C. Hernandez-Morales et al.   JOURNAL OF VIROLOGY

Disruption of the GDP-mannose synthesis pathway in Streptomyces coelicolor results in antibiotic hyper-susceptible phenotypes

(2018) Robert Howlett et al.   MICROBIOLOGY-SGM

Mycobacteriophage Fruitloop gp52 inactivates Wag31 (DivIVA) to prevent heterotypic superinfection

(2018) Ching-Chung Ko et al.   MOLECULAR MICROBIOLOGY

Glycointeractions in bacterial pathogenesis

(2018) Jessica Poole et al.   NATURE REVIEWS MICROBIOLOGY

Identification and biosynthesis of thymidine hypermodifications in the genomic DNA of widespread bacterial viruses

(2018) Yan-Jiun Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy

(2018) Frank Oechslin   Viruses-Basel

Regulatory protein SrpA controls phage infection and core cellular processes in Pseudomonas aeruginosa

(2018) Jiajia You et al.   Nature Communications

A fast and reliable method for monitoring of prophage-activating chemicals

(2018) Juan Xu et al.   Microbial Biotechnology

Cor interacts with outer membrane proteins to exclude FhuA-dependent phages

(2018) Emma S. Arguijo-Hernández et al.   ARCHIVES OF VIROLOGY

Emergence of Global Antibiotic Resistance

(2018) Martha Shawn Morehead et al.   PRIMARY CARE

PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures

(2018) Daniel Gleditzsch et al.   RNA Biology

Cross-resistance is modular in bacteria–phage interactions

(2018) Rosanna C. T. Wright et al.   PLOS BIOLOGY

Survey on the phage resistance mechanisms displayed by a dairy Lactobacillus helveticus strain

(2017) Miriam Zago et al.   FOOD MICROBIOLOGY

Contribution of AcrAB-TolC to multidrug resistance in an Escherichia coli sequence type 131 isolate

(2017) Sabine Schuster et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Not a barrier but a key: How bacteriophages exploit host's O-antigen as an essential receptor to initiate infection

(2017) Nina K. Broeker et al.   MOLECULAR MICROBIOLOGY

Anti-CRISPR: discovery, mechanism and function

(2017) April Pawluk et al.   NATURE REVIEWS MICROBIOLOGY

Associations among Antibiotic and Phage Resistance Phenotypes in Natural and Clinical Escherichia coli Isolates

(2017) Richard C. Allen et al.   mBio

DISARM is a widespread bacterial defence system with broad anti-phage activities

(2017) Gal Ofir et al.   Nature Microbiology

Increase of efflux-mediated resistance in Pseudomonas aeruginosa during antibiotic treatment in patients suffering from nosocomial pneumonia

(2016) Mickaël Riou et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Synergistic interaction between phage therapy and antibiotics clears Pseudomonas aeruginosa infection in endocarditis and reduces virulence

(2016) Frank Oechslin et al.   JOURNAL OF INFECTIOUS DISEASES

Alternatives to antibiotics—a pipeline portfolio review

(2016) Lloyd Czaplewski et al.   LANCET INFECTIOUS DISEASES

The diversity-generating benefits of a prokaryotic adaptive immune system

(2016) Stineke van Houte et al.   NATURE

Toxin-antitoxin systems in bacterial growth arrest and persistence

(2016) Rebecca Page et al.   Nature Chemical Biology

Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems

(2016) Prarthana Mohanraju et al.   SCIENCE

Antimicrobial Resistance in Agriculture

(2016) Sophie Thanner et al.   mBio

Quorum Regulated Resistance of Vibrio cholerae against Environmental Bacteriophages

(2016) M. Mozammel Hoque et al.   Scientific Reports

Bacteria vs. Bacteriophages: Parallel Evolution of Immune Arsenals

(2016) Muhammad A. B. Shabbir et al.   Frontiers in Microbiology

Phage selection restores antibiotic sensitivity in MDR Pseudomonas aeruginosa

(2016) Benjamin K. Chan et al.   Scientific Reports

Parasite Exposure Drives Selective Evolution of Constitutive versus Inducible Defense

(2015) Edze R. Westra et al.   CURRENT BIOLOGY

Resistencia bacteriana a los antibióticos: una crisis global

(2015) Juan-Ignacio Alós   ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA

Coevolution with Bacteriophages Drives Genome-Wide Host Evolution and Constrains the Acquisition of Abiotic-Beneficial Mutations

(2015) Pauline D. Scanlan et al.   MOLECULAR BIOLOGY AND EVOLUTION

An updated evolutionary classification of CRISPR–Cas systems

(2015) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Virulence reduction in bacteriophage resistant bacteria

(2015) Marcela León et al.   Frontiers in Microbiology

BREX is a novel phage resistance system widespread in microbial genomes

(2014) T. Goldfarb et al.   EMBO JOURNAL

The fitness costs of antibiotic resistance mutations

(2014) Anita H. Melnyk et al.   Evolutionary Applications

Phenotypic Resistance and the Dynamics of Bacterial Escape from Phage Control

(2014) James J. Bull et al.   PLoS One

A Thermostable Salmonella Phage Endolysin, Lys68, with Broad Bactericidal Properties against Gram-Negative Pathogens in Presence of Weak Acids

(2014) Hugo Oliveira et al.   PLoS One

A phage protein that inhibits the bacterial ATPase required for type IV pilus assembly

(2014) I.-Y. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacteriophage therapy: a potential solution for the antibiotic resistance crisis

(2014) Zhabiz Golkar et al.   Journal of Infection in Developing Countries

Anti-biofilm agents: recent breakthrough against multi-drug resistantStaphylococcus aureus

(2014) Pooi Y. Chung et al.   Pathogens and Disease

Remarkable Mechanisms in Microbes to Resist Phage Infections

(2014) Ron L. Dy et al.   Annual Review of Virology

Bacteriophage Orphan DNA Methyltransferases: Insights from Their Bacterial Origin, Function, and Occurrence

(2013) James Murphy et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Fight evolution with evolution: plasmid-dependent phages with a wide host range prevent the spread of antibiotic resistance

(2013) Ville Ojala et al.   Evolutionary Applications

Phages of Staphylococcus aureus and their impact on host evolution

(2013) Guoqing Xia et al.   INFECTION GENETICS AND EVOLUTION

Revenge of the phages: defeating bacterial defences

(2013) Julie E. Samson et al.   NATURE REVIEWS MICROBIOLOGY

Characterising the biology of novel lytic bacteriophages infecting multidrug resistant Klebsiella pneumoniae

(2013) Agata Kęsik-Szeloch et al.   Virology Journal

Bacterial Exopolysaccharides: Functionality and Prospects

(2012) Uchechukwu Nwodo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sticky Situations: Key Components That Control Bacterial Surface Attachment

(2012) O. E. Petrova et al.   JOURNAL OF BACTERIOLOGY

Superinfection Exclusion Is an Active Virus-Controlled Function That Requires a Specific Viral Protein

(2012) S. Y. Folimonova   JOURNAL OF VIROLOGY

Spontaneous and transient defence against bacteriophage by phase-variable glucosylation of O-antigen inSalmonella entericaserovar Typhimurium

(2012) Minsik Kim et al.   MOLECULAR MICROBIOLOGY

Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system

(2012) Joe Bondy-Denomy et al.   NATURE

Phase variable genes of Campylobacter jejuni exhibit high mutation rates and specific mutational patterns but mutability is not the major determinant of population structure during host colonization

(2012) Christopher D. Bayliss et al.   NUCLEIC ACIDS RESEARCH

Staphylococcal pathogenicity island interference with helper phage reproduction is a paradigm of molecular parasitism

(2012) G. Ram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Repeatability and Contingency in the Evolution of a Key Innovation in Phage Lambda

(2012) J. R. Meyer et al.   SCIENCE

Bacteriophages and their Implications on Future Biotechnology: A Review

(2012) Irshad UL Haq et al.   Virology Journal

Success of a suicidal defense strategy against infection in a structured habitat

(2012) Masaki Fukuyo et al.   Scientific Reports

Innate and adaptive immunity in bacteria: mechanisms of programmed genetic variation to fight bacteriophages

(2011) David Bikard et al.   CURRENT OPINION IN IMMUNOLOGY

Host-parasite coevolutionary arms races give way to fluctuating selection

(2011) Alex R. Hall et al.   ECOLOGY LETTERS

Co-evolution with lytic phage selects for the mucoid phenotype of Pseudomonas fluorescens SBW25

(2011) Pauline Deirdre Scanlan et al.   ISME Journal

Bacteriophage F336 Recognizes the Capsular Phosphoramidate Modification of Campylobacter jejuni NCTC11168

(2011) M. C. H. Sorensen et al.   JOURNAL OF BACTERIOLOGY

Improved Adsorption of an Enterococcus faecalis Bacteriophage ΦEF24C with a Spontaneous Point Mutation

(2011) Jumpei Uchiyama et al.   PLoS One

RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions

(2011) B. Wiedenheft et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploiting the Role of TolC in Pathogenicity: Identification of a Bacteriophage for Eradication of Salmonella Serovars from Poultry

(2010) V. Ricci et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The phage-host arms race: Shaping the evolution of microbes

(2010) Adi Stern et al.   BIOESSAYS

Escherichia coli rnlA and rnlB Compose a Novel Toxin-Antitoxin System

(2010) M. Koga et al.   GENETICS

The CRISPR System: Small RNA-Guided Defense in Bacteria and Archaea

(2010) Fedor V. Karginov et al.   MOLECULAR CELL

Genetic basis of infectivity evolution in a bacteriophage

(2010) PAULINE D. SCANLAN et al.   MOLECULAR ECOLOGY

Bacteriophage resistance mechanisms

(2010) Simon J. Labrie et al.   NATURE REVIEWS MICROBIOLOGY

Bacteriophage-Resistant Staphylococcus aureus Mutant Confers Broad Immunity against Staphylococcal Infection in Mice

(2010) Rosanna Capparelli et al.   PLoS One

A Forward-Genetic Screen and Dynamic Analysis of Lambda Phage Host-Dependencies Reveals an Extensive Interaction Network and a New Anti-Viral Strategy

(2010) Nathaniel D. Maynard et al.   PLoS Genetics

A Brief History of the Antibiotic Era: Lessons Learned and Challenges for the Future

(2010) Rustam I. Aminov   Frontiers in Microbiology

Regulation and physiological function of multidrug efflux pumps in Escherichia coli and Salmonella

(2009) Kunihiko Nishino et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The Structure and Biological Aspects of Peptide Antibiotic Microcin J25

(2009) Paula Vincent et al.   CURRENT MEDICINAL CHEMISTRY

The tail sheath structure of bacteriophage T4: a molecular machine for infecting bacteria

(2009) Anastasia A Aksyuk et al.   EMBO JOURNAL

Comparative analysis of the widespread and conserved PB1-like viruses infectingPseudomonas aeruginosa

(2009) Pieter-Jan Ceyssens et al.   ENVIRONMENTAL MICROBIOLOGY

The Genome of Bacillus subtilis Bacteriophage SPO1

(2009) Charles R. Stewart et al.   JOURNAL OF MOLECULAR BIOLOGY

The phage abortive infection system, ToxIN, functions as a protein–RNA toxin–antitoxin pair

(2009) Peter C. Fineran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of some phenotypic traits of feces-borne temperate lambdoid bacteriophages from different immunity groups: a high incidence of cor+, FhuA-dependent phages

(2008) Javier Hernández-Sánchez et al.   ARCHIVES OF VIROLOGY

Antimicrobial resistance in Europe and its potential impact on empirical therapy

(2008) G.M. Rossolini et al.   CLINICAL MICROBIOLOGY AND INFECTION

Phage-resistance linked to cell heterogeneity in the commercial strain Lactobacillus delbrueckii subsp. lactis Ab1

(2008) Viviana B. Suárez et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Wag31, a homologue of the cell division protein DivIVA, regulates growth, morphology and polar cell wall synthesis in mycobacteria

(2008) C.-M. Kang et al.   MICROBIOLOGY-SGM

CRISPRcompar: a website to compare clustered regularly interspaced short palindromic repeats

(2008) I. Grissa et al.   NUCLEIC ACIDS RESEARCH

Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes

(2008) S. J. J. Brouns et al.   SCIENCE

The lactococcal abortive infection protein AbiP is membrane-anchored and binds nucleic acids

(2008) Susana Domingues et al.   VIROLOGY

Restriction Endonuclease Inhibitor IPI* of Bacteriophage T4: A Novel Structure for a Dedicated Target

(2007) Dalin Rifat et al.   JOURNAL OF MOLECULAR BIOLOGY