Delivery of CRISPR-Cas systems using phage-based vectors

The arms race between bacteria and their phage foes

(2020) Hannah G. Hampton et al.   NATURE

Phage diversity, genomics and phylogeny

(2020) Moïra B. Dion et al.   NATURE REVIEWS MICROBIOLOGY

Options to Reform the European Union Legislation on GMOs: Scope and Definitions

(2020) Dennis Eriksson et al.   TRENDS IN BIOTECHNOLOGY

Clinical and economic impact of methicillin-resistant Staphylococcus aureus: a multicentre study in China

(2020) Xuemei Zhen et al.   Scientific Reports

CRISPR-Cas Systems and the Paradox of Self-Targeting Spacers

(2020) Franziska Wimmer et al.   Frontiers in Microbiology

Endogenous Type I CRISPR-Cas: From Foreign DNA Defense to Prokaryotic Engineering

(2020) Yanli Zheng et al.   Frontiers in Bioengineering and Biotechnology

In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials

(2020) Kurt Selle et al.   mBio

Targeting Plasmids to Limit Acquisition and Transmission of Antimicrobial Resistance

(2020) Corneliu Ovidiu Vrancianu et al.   Frontiers in Microbiology

Phage-Derived Antibacterials: Harnessing the Simplicity, Plasticity, and Diversity of Phages

(2019) Bi-o Kim et al.   Viruses-Basel

Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review

(2019) Krystyna Dąbrowska   MEDICINAL RESEARCH REVIEWS

Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria

(2019) Kaitlyn E. Kortright et al.   Cell Host & Microbe

Determinants of Phage Host Range in Staphylococcus Species

(2019) Abraham G. Moller et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus

(2019) Rebekah M. Dedrick et al.   NATURE MEDICINE

Bacteriophages engineered to display foreign peptides may become short‐circulating phages

(2019) Katarzyna Hodyra‐Stefaniak et al.   Microbial Biotechnology

Bacteriophage Production Models: An Overview

(2019) Rodrigo García et al.   Frontiers in Microbiology

Encapsulation of E. coli phage ZCEC5 in chitosan–alginate beads as a delivery system in phage therapy

(2019) Abdallah S. Abdelsattar et al.   AMB Express

Conjugative delivery of CRISPR-Cas9 for the selective depletion of antibiotic-resistant enterococci

(2019) Marinelle Rodrigues et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis

(2019) Kevin Yehl et al.   CELL

Pharmacologically Aware Phage Therapy: Pharmacodynamic and Pharmacokinetic Obstacles to Phage Antibacterial Action in Animal and Human Bodies

(2019) Krystyna Dąbrowska et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

CRISPR-Cas9 modified bacteriophage for treatment of Staphylococcus aureus induced osteomyelitis and soft tissue infection

(2019) Leah H. Cobb et al.   PLoS One

Efficacy of a phage cocktail in controlling phage resistance development in multidrug resistant Acinetobacter baumannii

(2019) Yuyu Yuan et al.   VIRUS RESEARCH

Reprogramming Bacteriophage Host Range through Structure-Guided Design of Chimeric Receptor Binding Proteins

(2019) Matthew Dunne et al.   Cell Reports

Biological challenges of phage therapy and proposed solutions: a literature review

(2019) Katherine M Caflisch et al.   Expert Review of Anti-Infective Therapy

Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants

(2019) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Phages as friends and enemies in food processing

(2018) Alessandra Gonçalves de Melo et al.   CURRENT OPINION IN BIOTECHNOLOGY

Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy

(2018) Frank Oechslin   Viruses-Basel

Engineering Bacteriophages as Versatile Biologics

(2018) Samuel Kilcher et al.   TRENDS IN MICROBIOLOGY

CRISPR-Cas9 technology: applications in genome engineering, development of sequence-specific antimicrobials, and future prospects

(2017) César de la Fuente-Núñez et al.   Integrative Biology

Extending the Host Range of Bacteriophage Particles for DNA Transduction

(2017) Ido Yosef et al.   MOLECULAR CELL

Capsids and Genomes of Jumbo-Sized Bacteriophages Reveal the Evolutionary Reach of the HK97 Fold

(2017) Jianfei Hua et al.   mBio

Novel “Superspreader” Bacteriophages Promote Horizontal Gene Transfer by Transformation

(2017) Eric C. Keen et al.   mBio

Genome Engineering of Virulent Lactococcal Phages Using CRISPR-Cas9

(2017) Marie-Laurence Lemay et al.   ACS Synthetic Biology

Phage Therapy in Bacterial Infections Treatment: One Hundred Years After the Discovery of Bacteriophages

(2016) Agata Anna Cisek et al.   CURRENT MICROBIOLOGY

Encapsulation of Bacteriophage in Liposome Accentuates Its Entry in to Macrophage and Shields It from Neutralizing Antibodies

(2016) Saloni Singla et al.   PLoS One

Liposome-Encapsulated Bacteriophages for Enhanced Oral Phage Therapy against Salmonella spp.

(2015) Joan Colom et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Engineered Phagemids for Nonlytic, Targeted Antibacterial Therapies

(2015) Russell J. Krom et al.   NANO LETTERS

Temperate and lytic bacteriophages programmed to sensitize and kill antibiotic-resistant bacteria

(2015) Ido Yosef et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases

(2014) Robert J Citorik et al.   NATURE BIOTECHNOLOGY

Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials

(2014) David Bikard et al.   NATURE BIOTECHNOLOGY

Improving the Safety of Staphylococcus aureus Polyvalent Phages by Their Production on a Staphylococcus xylosus Strain

(2014) Lynn El Haddad et al.   PLoS One

Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems

(2014) A. A. Gomaa et al.   mBio

Revenge of the phages: defeating bacterial defences

(2013) Julie E. Samson et al.   NATURE REVIEWS MICROBIOLOGY

Cytotoxic Chromosomal Targeting by CRISPR/Cas Systems Can Reshape Bacterial Genomes and Expel or Remodel Pathogenicity Islands

(2013) Reuben B. Vercoe et al.   PLoS Genetics