Catalytic and Electrocatalytic Mechanisms of Cytochromes P450 in the Development of Biosensors and Bioreactors

Improving the Efficiency of Electrocatalysis of Cytochrome P450 3A4 by Modifying the Electrode with Membrane Protein Streptolysin O for Studying the Metabolic Transformations of Drugs

(2023) Polina I. Koroleva et al.   Biosensors-Basel

Immobilization of cytochrome P450 enzymes onto magnetic beads: An approach to drug metabolism and biocatalysis

(2023) Izadora Liranço Furlani et al.   Talanta Open

Preparative Production of Functionalized (N- and O-Heterocyclic) Polycyclic Aromatic Hydrocarbons by Human Cytochrome P450 3A4 in a Bioreactor

(2022) Matic Srdič et al.   Biomolecules

The Combination of Electrochemistry and Microfluidic Technology in Drug Metabolism Studies

(2022) Isobel Grint et al.   ChemistryOpen

Enzymology on an Electrode and in a Nanopore: Analysis Algorithms, Enzyme Kinetics, and Perspectives

(2022) V. V. Shumyantseva et al.   BioNanoScience

Approaches for increasing the electrocatalitic efficiency of cytochrome P450 3A4

(2022) Victoria V. Shumyantseva et al.   BIOELECTROCHEMISTRY

Self-Sufficient Class VII Cytochromes P450: From Full-Length Structure to Synthetic Biology Applications

(2021) Danilo Correddu et al.   TRENDS IN BIOTECHNOLOGY

Electrocatalysis by Heme Enzymes—Applications in Biosensing

(2021) Lidia Zuccarello et al.   Catalysts

Enzymatic Regio- and Enantioselective C–H Oxyfunctionalization of Fatty Acids

(2021) Hao Chen et al.   ACS Catalysis

An Overview of Cytochrome P450 Immobilization Strategies for Drug Metabolism Studies, Biosensing, and Biocatalytic Applications: Challenges and Opportunities

(2021) Donya Valikhani et al.   ACS Catalysis

Reactive metabolites: Generation and estimation with electrochemistry based analytical strategy as an emerging screening tool

(2020) Maria Bandookwala et al.   Current Analytical Chemistry

Riboflavin Is Directly Involved in N‐Dealkylation Catalyzed by Bacterial Cytochrome P450 Monooxygenases

(2020) Chengchang Zhang et al.   CHEMBIOCHEM

Roughened graphite biointerfaced with P450 liver microsomes: Surface and electrochemical characterizations

(2020) Austin Walker et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Oxygen Surrogate Systems for Supporting Human Drug-Metabolizing Cytochrome P450 Enzymes

(2020) Silja J. Strohmaier et al.   DRUG METABOLISM AND DISPOSITION

Surface charge-controlled electron transfer and catalytic behavior of immobilized cytochrome P450 BM3 inside dendritic mesoporous silica nanoparticles

(2020) Qumei Dai et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Natural Compounds as Pharmaceuticals: The Key Role of Cytochromes P450 Reactivity

(2020) Giovanna Di Nardo et al.   TRENDS IN BIOCHEMICAL SCIENCES

Engineered human CYP2C9 and its main polymorphic variants for bioelectrochemical measurements of catalytic response

(2020) Paola Panicco et al.   BIOELECTROCHEMISTRY

Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8

(2019) Helinä Kahma et al.   DRUG METABOLISM AND DISPOSITION

Use of bioconjugation with cytochrome P450 enzymes

(2018) Julie Ducharme et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Improved electrocatalytic metabolite production and drug biosensing by human liver microsomes immobilized on amine-functionalized magnetic nanoparticles

(2018) Rajasekhara Nerimetla et al.   ELECTROCHIMICA ACTA

The relationships between cytochromes P450 and H 2 O 2 : Production, reaction, and inhibition

(2018) Matthew E. Albertolle et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Polydopamine functionalized nanoporous graphene foam as nanoreactor for efficient electrode-driven metabolism of steroid hormones

(2018) Xuan Xu et al.   BIOSENSORS & BIOELECTRONICS

From electrochemistry to enzyme kinetics of cytochrome P450

(2018) Victoria V. Shumyantseva et al.   BIOSENSORS & BIOELECTRONICS

Dioxygen Activation by the Biofuel-Generating Cytochrome P450 OleT

(2018) Courtney E. Wise et al.   ACS Catalysis

Mechanistic Insights into Voltage-Driven Biocatalysis of a Cytochrome P450 Bactosomal Film on a Self-Assembled Monolayer

(2017) Rajasekhara Nerimetla et al.   ACS Catalysis

Nanoporous Structure of Gold Electrode Fabricated by Anodization and Its Efficacy for Direct Electrochemistry of Human Cytochrome P450

(2016) Yasuhiro Mie et al.   CHEMISTRY LETTERS

Enzymatic reactions in confined environments

(2016) Andreas Küchler et al.   Nature Nanotechnology

Application of nanodisc technology for direct electrochemical investigation of plant cytochrome P450s and their NADPH P450 oxidoreductase

(2016) Krutika Bavishi et al.   Scientific Reports

A Simple Construction of Electrochemical Liver Microsomal Bioreactor for Rapid Drug Metabolism and Inhibition Assays

(2015) Charuksha Walgama et al.   ANALYTICAL CHEMISTRY

Electrocatalysis by subcellular liver fractions bound to carbon nanostructures for stereoselective green drug metabolite synthesis

(2015) Rajasekhara Nerimetla et al.   CHEMICAL COMMUNICATIONS

Enhanced Enzymatic Reactivity for Electrochemically Driven Drug Metabolism by Confining Cytochrome P450 Enzyme in TiO2 Nanotube Arrays

(2014) Jusheng Lu et al.   ANALYTICAL CHEMISTRY

Cofactor-Free Light-Driven Whole-Cell Cytochrome P450 Catalysis

(2014) Jong Hyun Park et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cytochromes P450 as promising catalysts for biotechnological application: chances and limitations

(2014) Rita Bernhardt et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Light-driven biocatalysis with cytochrome P450 peroxygenases

(2013) Marco Girhard et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

(2013) Ulrich M. Zanger et al.   PHARMACOLOGY & THERAPEUTICS

The monooxygenase, peroxidase, and peroxygenase properties of cytochrome P450

(2012) Eugene G. Hrycay et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Practical Application of Cytochrome P450

(2012) Toshiyuki Sakaki   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Cytochrome P450 (CYP) enzymes and the development of CYP biosensors

(2012) Elizabeth Schneider et al.   BIOSENSORS & BIOELECTRONICS

Electrochemical determination of cocaine using screen-printed cytochrome P450 2B4 based biosensors

(2012) Laura Asturias-Arribas et al.   TALANTA

Cytochrome P450 monooxygenases: an update on perspectives for synthetic application

(2011) Vlada B. Urlacher et al.   TRENDS IN BIOTECHNOLOGY

The interaction of microsomal cytochrome P450 2B4 with its redox partners, cytochrome P450 reductase and cytochrome b5

(2010) Sang-Choul Im et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation

(2010) Santosh Kumar   Expert Opinion on Drug Metabolism & Toxicology

Pharmacogenetics of Phase I and Phase II Drug Metabolism

(2009) Severine Crettol et al.   CURRENT PHARMACEUTICAL DESIGN