Engineered human CYP2C9 and its main polymorphic variants for bioelectrochemical measurements of catalytic response

Polymorphisms of genes encoding drug transporters or cytochrome P450 enzymes and association with clinical response in cancer patients: a systematic review

(2019) Inthuorn Kulma et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Modulation of the interaction between human P450 3A4 and B. megaterium reductase via engineered loops

(2018) Silvia Castrignanò et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Influence of inter-domain dynamics and surrounding environment flexibility on the direct electrochemistry and electrocatalysis of self-sufficient cytochrome P450 3A4-BMR chimeras

(2018) Silvia Castrignanò et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Human Cytochrome P450 3A4 as a Biocatalyst: Effects of the Engineered Linker in Modulation of Coupling Efficiency in 3A4-BMR Chimeras

(2017) Danilo Degregorio et al.   Frontiers in Pharmacology

Electrochemistry of Canis familiaris cytochrome P450 2D15 with gold nanoparticles: An alternative to animal testing in drug discovery

(2015) Francesco Rua et al.   BIOELECTROCHEMISTRY

Bioelectrochemistry as a tool for the study of aromatization of steroids by human aromatase

(2015) Giovanna Di Nardo et al.   ELECTROCHEMISTRY COMMUNICATIONS

Electrochemical Detection of Human Cytochrome P450 2A6 Inhibition: A Step toward Reducing Dependence on Smoking

(2014) Silvia Castrignanò et al.   ANALYTICAL CHEMISTRY

p-Aminothiophenol modification on gold surface improves stability for electrochemically driven cytochrome P450 microsome activity

(2013) Yasuhiro Mie et al.   ELECTROCHIMICA ACTA

Functional characterization of 32 CYP2C9 allelic variants

(2013) Y Niinuma et al.   PHARMACOGENOMICS JOURNAL

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

(2013) Ulrich M. Zanger et al.   PHARMACOLOGY & THERAPEUTICS

CYP450 Pharmacogenetic treatment strategies for antipsychotics: A review of the evidence

(2013) Dana Ravyn et al.   SCHIZOPHRENIA RESEARCH

Cytochrome P450 (CYP) enzymes and the development of CYP biosensors

(2012) Elizabeth Schneider et al.   BIOSENSORS & BIOELECTRONICS

Engineering Macaca fascicularis cytochrome P450 2C20 to reduce animal testing for new drugs

(2012) Francesco Rua et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Enzyme-Based Amperometric Platform to Determine the Polymorphic Response in Drug Metabolism by Cytochromes P450

(2011) Paola Panicco et al.   ANALYTICAL CHEMISTRY

Understanding uncoupling in the multiredox centre P450 3A4–BMR model system

(2010) Danilo Degregorio et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Modulating the coupling efficiency of human cytochrome P450 CYP3A4 at electrode surfaces through protein engineering

(2008) Vikash R. Dodhia et al.   ELECTROCHEMISTRY COMMUNICATIONS

Prediction of the Effects of Genetic Polymorphism on the Pharmacokinetics of CYP2C9 Substrates from In Vitro Data

(2008) Makiko Kusama et al.   PHARMACEUTICAL RESEARCH

Electrochemistry of cytochrome P450 enzyme on nanoparticle-containing membrane-coated electrode and its applications for drug sensing

(2007) Songqin Liu et al.   ANALYTICAL BIOCHEMISTRY