Electrocatalysis by subcellular liver fractions bound to carbon nanostructures for stereoselective green drug metabolite synthesis

A Simple Construction of Electrochemical Liver Microsomal Bioreactor for Rapid Drug Metabolism and Inhibition Assays

(2015) Charuksha Walgama et al.   ANALYTICAL CHEMISTRY

Elucidating organ-specific metabolic toxicity chemistry from electrochemiluminescent enzyme/DNA arrays and bioreactor bead-LC-MS/MS

(2015) Dhanuka P. Wasalathanthri et al.   Chemical Science

Unusual Cytochrome P450 Enzymes and Reactions

(2013) F. Peter Guengerich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tuning the Electrocatalytic Efficiency of Heme-Protein Films by Controlled Immobilization on Pyrene-Functionalized Nanostructure Electrodes

(2013) Charuksha Walgama et al.   JOURNAL OF THE ELECTROCHEMICAL SOCIETY

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

(2013) Ulrich M. Zanger et al.   PHARMACOLOGY & THERAPEUTICS

Cytochrome P450 (CYP) enzymes and the development of CYP biosensors

(2012) Elizabeth Schneider et al.   BIOSENSORS & BIOELECTRONICS

Order-of-magnitude enhancement of an enzymatic hydrogen-air fuel cell based on pyrenyl carbon nanostructures

(2012) Sadagopan Krishnan et al.   Chemical Science

Cytochromes P450 as useful biocatalysts: addressing the limitations

(2011) Elaine O'Reilly et al.   CHEMICAL COMMUNICATIONS

Cytochrome P450: taming a wild type enzyme

(2011) Sang Taek Jung et al.   CURRENT OPINION IN BIOTECHNOLOGY

Bioelectronic Delivery of Electrons to Cytochrome P450 Enzymes

(2011) Sadagopan Krishnan et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Efficient Bioelectronic Actuation of the Natural Catalytic Pathway of Human Metabolic Cytochrome P450s

(2011) Sadagopan Krishnan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Managing the challenge of chemically reactive metabolites in drug development

(2011) B. Kevin Park et al.   NATURE REVIEWS DRUG DISCOVERY

Pharmacogenetics, Pharmacogenomics, and Individualized Medicine

(2011) Q. Ma et al.   PHARMACOLOGICAL REVIEWS

Electrochemically Driven Drug Metabolism by Membranes Containing Human Cytochrome P450

(2009) Yasuhiro Mie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synergistic Metabolic Toxicity Screening Using Microsome/DNA Electrochemiluminescent Arrays and Nanoreactors

(2008) Sadagopan Krishnan et al.   ANALYTICAL CHEMISTRY

Modulating the coupling efficiency of human cytochrome P450 CYP3A4 at electrode surfaces through protein engineering

(2008) Vikash R. Dodhia et al.   ELECTROCHEMISTRY COMMUNICATIONS