Development of an Automated, High-Throughput Methodology for Native Mass Spectrometry and Collision-Induced Unfolding

Online Collision-Induced Unfolding of Therapeutic Monoclonal Antibody Glyco-Variants through Direct Hyphenation of Cation Exchange Chromatography with Native Ion Mobility–Mass Spectrometry

(2023) Guusje van Schaick et al.   Analytical Chemistry

High-Resolution Demultiplexing (HRdm) Ion Mobility Spectrometry–Mass Spectrometry for Aspartic and Isoaspartic Acid Determination and Screening

(2022) Karen E. Butler et al.   ANALYTICAL CHEMISTRY

Ion Mobility–Mass Spectrometry Reveals the Structures and Stabilities of Biotherapeutic Antibody Aggregates

(2022) Daniel D. Vallejo et al.   ANALYTICAL CHEMISTRY

Native Ambient Mass Spectrometry Enables Analysis of Intact Endogenous Protein Assemblies up to 145 kDa Directly from Tissue

(2022) Oliver J. Hale et al.   ANALYTICAL CHEMISTRY

Structural Studies of a Stapled Peptide with Native Ion Mobility-Mass Spectrometry and Transition Metal Ion Förster Resonance Energy Transfer in the Gas Phase

(2022) Ri Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ion Mobility-Mass Spectrometry Coupled to Droplet Microfluidics for Rapid Protein Structure Analysis and Drug Discovery

(2022) Cara I. D’Amico et al.   ANALYTICAL CHEMISTRY

High-Throughput Mass Spectrometry for Biopharma: A Universal Modality and Target Independent Analytical Method for Accurate Biomolecule Characterization

(2022) Iain D. G. Campuzano et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Performance evaluation of in-source ion activation hardware for collision-induced unfolding of proteins and protein complexes on a drift tube ion mobility-mass spectrometer

(2022) Varun V. Gadkari et al.   ANALYST

Gas-Phase Unfolding of Protein Complexes Distinguishes Conformational Isomers

(2022) Stacey Nash et al.   Journal of the American Chemical Society

Ultrahigh-Throughput Intact Protein Analysis with Acoustic Ejection Mass Spectrometry

(2022) Adway O. Zacharias et al.   Journal of the American Society for Mass Spectrometry

Ion mobility–mass spectrometry reveals the role of peripheral myelin protein dimers in peripheral neuropathy

(2021) Sarah M. Fantin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving the Speed and Selectivity of Newborn Screening Using Ion Mobility Spectrometry–Mass Spectrometry

(2021) James N. Dodds et al.   ANALYTICAL CHEMISTRY

Collision-Induced Unfolding Reveals Stability Differences in Infliximab Therapeutics under Native and Heat Stress Conditions

(2021) Daniel D. Vallejo et al.   ANALYTICAL CHEMISTRY

Collision Cross Sections for Native Proteomics: Challenges and Opportunities

(2021) Brandon T. Ruotolo   JOURNAL OF PROTEOME RESEARCH

Multiplexed Screening of Thousands of Natural Products for Protein–Ligand Binding in Native Mass Spectrometry

(2021) Giang T. H. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Collision-Induced Unfolding of Native-like Protein Ions Within a Trapped Ion Mobility Spectrometry Device

(2021) Nicholas B. Borotto et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Collision Cross Sections of Charge-Reduced Proteins and Protein Complexes: A Database for Collision Cross Section Calibration

(2020) Alyssa Q. Stiving et al.   ANALYTICAL CHEMISTRY

Native vs Denatured: An in Depth Investigation of Charge State and Isotope Distributions

(2020) Jared O. Kafader et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry

(2020) Zachary L. VanAernum et al.   Nature Protocols

High-throughput antibody screening from complex matrices using intact protein electrospray mass spectrometry

(2020) William S. Sawyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

THE IMS PARADOX: A PERSPECTIVE ON STRUCTURAL ION MOBILITY‐MASS SPECTROMETRY

(2020) Jacob W. McCabe et al.   MASS SPECTROMETRY REVIEWS

Toward Automation of Collision-Induced Unfolding Experiments through Online Size Exclusion Chromatography Coupled to Native Mass Spectrometry

(2020) Evolène Deslignière et al.   ANALYTICAL CHEMISTRY

Collision-Induced Unfolding Differentiates Functional Variants of the KCNQ1 Voltage Sensor Domain

(2020) Sarah M. Fantin et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Compaction of RNA Hairpins and Their Kissing Complexes in Native Electrospray Mass Spectrometry

(2020) Josephine Abi-Ghanem et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins

(2019) Xeni Miliara et al.   Nature Communications

CIUSuite 2: Next-Generation Software for the Analysis of Gas-Phase Protein Unfolding Data

(2019) Daniel A. Polasky et al.   ANALYTICAL CHEMISTRY

RapidFire BLAZE-Mode Is Boosting ESI-MS Toward High-Throughput-Screening

(2019) Tom Bretschneider et al.   SLAS Technology

A Modified Drift Tube Ion Mobility-Mass Spectrometer for Charge-Multiplexed Collision-Induced Unfolding

(2019) Daniel D. Vallejo et al.   ANALYTICAL CHEMISTRY

Collision induced unfolding of isolated proteins in the gas phase: past, present, and future

(2018) Sugyan M Dixit et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Collision induced unfolding detects subtle differences in intact antibody glycoforms and associated fragments

(2018) Yuwei Tian et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Size Exclusion Chromatography-Ion Mobility-Mass Spectrometry Coupling: a Step Toward Structural Biology

(2017) Guillaume Van der Rest et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Insights from native mass spectrometry approaches for top- and middle- level characterization of site-specific antibody-drug conjugates

(2017) Thomas Botzanowski et al.   mAbs

Determining Membrane Protein–Lipid Binding Thermodynamics Using Native Mass Spectrometry

(2016) Xiao Cong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Early stages of insulin fibrillogenesis examined with ion mobility mass spectrometry and molecular modelling

(2015) Harriet Cole et al.   ANALYST

Collision Induced Unfolding of Intact Antibodies: Rapid Characterization of Disulfide Bonding Patterns, Glycosylation, and Structures

(2015) Yuwei Tian et al.   ANALYTICAL CHEMISTRY

E1 of α-ketoglutarate dehydrogenase defendsMycobacterium tuberculosisagainst glutamate anaplerosis and nitroxidative stress

(2015) Christina Maksymiuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Collision Cross Sections for Structural Proteomics

(2015) Erik G. Marklund et al.   STRUCTURE

Native Electrospray Mass Spectrometry of DNA G-Quadruplexes in Potassium Solution

(2014) Adrien Marchand et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Robotically Assisted Titration Coupled to Ion Mobility-Mass Spectrometry Reveals the Interface Structures and Analysis Parameters Critical for Multiprotein Topology Mapping

(2013) Yueyang Zhong et al.   ANALYTICAL CHEMISTRY

mMass as a Software Tool for the Annotation of Cyclic Peptide Tandem Mass Spectra

(2012) Timo H. J. Niedermeyer et al.   PLoS One

mMass3: A Cross-Platform Software Environment for Precise Analysis of Mass Spectrometric Data

(2010) Martin Strohalm et al.   ANALYTICAL CHEMISTRY

Electrospray mass spectrometry to study drug-nucleic acids interactions

(2008) Frédéric Rosu et al.   BIOCHIMIE

Native mass spectrometry: a bridge between interactomics and structural biology

(2008) Albert J R Heck   NATURE METHODS

mMass data miner: an open source alternative for mass spectrometric data analysis

(2008) Martin Strohalm et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY