Gas-Phase Unfolding of Protein Complexes Distinguishes Conformational Isomers

Investigation of Charge-State-Dependent Compaction of Protein Ions with Native Ion Mobility–Mass Spectrometry and Theory

(2022) Amber D. Rolland et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

An Improved Calibration Approach for Traveling Wave Ion Mobility Spectrometry: Robust, High-Precision Collision Cross Sections

(2021) K. Richardson et al.   ANALYTICAL CHEMISTRY

Catalytic Cross Talk between Key Peptide Fragments That Couple Alzheimer’s Disease with Amyotrophic Lateral Sclerosis

(2021) Veronica Laos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Variable-Temperature Electrospray Ionization for Temperature-Dependent Folding/Refolding Reactions of Proteins and Ligand Binding

(2021) Jacob W. McCabe et al.   ANALYTICAL CHEMISTRY

Mobile Protons Limit the Stability of Salt Bridges in the Gas Phase: Implications for the Structures of Electrosprayed Protein Ions

(2021) Lars Konermann et al.   JOURNAL OF PHYSICAL CHEMISTRY B

An Integrated Mass Spectrometry and Molecular Dynamics Simulations Approach Reveals the Spatial Organization Impact of Metal-Binding Sites on the Stability of Metal-Depleted Metallothionein-2 Species

(2021) Manuel David Peris-Díaz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Biology in the Clouds: The WeNMR-EOSC Ecosystem

(2021) Rodrigo V. Honorato et al.   Frontiers in Molecular Biosciences

Ion Mobility Mass Spectrometry Uncovers the Impact of the Patterning of Oppositely Charged Residues on the Conformational Distributions of Intrinsically Disordered Proteins

(2019) Rebecca Beveridge et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CIUSuite 2: Next-Generation Software for the Analysis of Gas-Phase Protein Unfolding Data

(2019) Daniel A. Polasky et al.   ANALYTICAL CHEMISTRY

A Cyclic Ion Mobility – Mass Spectrometry System

(2019) Kevin Giles et al.   ANALYTICAL CHEMISTRY

Computational insights into compaction of gas-phase protein and protein complex ions in native ion mobility-mass spectrometry

(2019) Amber D. Rolland et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Testing the Robustness of Solution Force Fields for MD Simulations on Gaseous Protein Ions

(2019) Justin H. Lee et al.   JOURNAL OF PHYSICAL CHEMISTRY B

SLIM Ultrahigh Resolution Ion Mobility Spectrometry Separations of Isotopologues and Isotopomers Reveal Mobility Shifts due to Mass Distribution Changes

(2019) Roza Wojcik et al.   ANALYTICAL CHEMISTRY

Collision-Induced Unfolding Is Sensitive to the Polarity of Proteins and Protein Complexes

(2019) Seoyeon Hong et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Structural Heterogeneity in the Preamyloid Oligomers of β-2-Microglobulin

(2019) Tyler M. Marcinko et al.   JOURNAL OF MOLECULAR BIOLOGY

Trajectory Taken by Dimeric Cu/Zn Superoxide Dismutase through the Protein Unfolding and Dissociation Landscape Is Modulated by Salt Bridge Formation

(2019) Luke McAlary et al.   ANALYTICAL CHEMISTRY

Revealing the Dimeric Crystal and Solution Structure of β-Lactoglobulin at pH 4 and Its pH and Salt Dependent Monomer–Dimer Equilibrium

(2018) Sanaullah Khan et al.   BIOMACROMOLECULES

Collision induced unfolding of isolated proteins in the gas phase: past, present, and future

(2018) Sugyan M Dixit et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Fourier Transform-Ion Mobility-Orbitrap Mass Spectrometer: A Next-Generation Instrument for Native Mass Spectrometry

(2018) Michael L. Poltash et al.   ANALYTICAL CHEMISTRY

A new era for understanding amyloid structures and disease

(2018) Matthew G. Iadanza et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Gas-phase protein salt bridge stabilities from collisional activation and electron transfer dissociation

(2017) Zhe Zhang et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Small molecule-mediated inhibition of β-2-microglobulin-based amyloid fibril formation

(2017) Tyler M. Marcinko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Dynamics Simulations on Gas-Phase Proteins with Mobile Protons: Inclusion of All-Atom Charge Solvation

(2017) Lars Konermann   JOURNAL OF PHYSICAL CHEMISTRY B

Photoelectron Transfer Dissociation Reveals Surprising Favorability of Zwitterionic States in Large Gaseous Peptides and Proteins

(2017) James Bonner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Collidoscope: An Improved Tool for Computing Collisional Cross-Sections with the Trajectory Method

(2017) Simon A. Ewing et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes

(2016) G.C.P. van Zundert et al.   JOURNAL OF MOLECULAR BIOLOGY

Collision-Induced Dissociation of Electrosprayed Protein Complexes: An All-Atom Molecular Dynamics Model with Mobile Protons

(2016) Vlad Popa et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Chemical Probes and Engineered Constructs Reveal a Detailed Unfolding Mechanism for a Solvent-Free Multidomain Protein

(2016) Joseph D. Eschweiler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluation of Ion Mobility-Mass Spectrometry for Comparative Analysis of Monoclonal Antibodies

(2016) Carly N. Ferguson et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Salt Bridge Rearrangement (SaBRe) Explains the Dissociation Behavior of Noncovalent Complexes

(2016) Rachel R. Ogorzalek Loo et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Mass spectrometry locates local and allosteric conformational changes that occur on cofactor binding

(2016) Rebecca Beveridge et al.   Nature Communications

Collision Induced Unfolding of Intact Antibodies: Rapid Characterization of Disulfide Bonding Patterns, Glycosylation, and Structures

(2015) Yuwei Tian et al.   ANALYTICAL CHEMISTRY

MDTraj: A Modern Open Library for the Analysis of Molecular Dynamics Trajectories

(2015) Robert T. McGibbon et al.   BIOPHYSICAL JOURNAL

Ion Mobility-Mass Spectrometry Reveals Highly-Compact Intermediates in the Collision Induced Dissociation of Charge-Reduced Protein Complexes

(2015) Russell E. Bornschein et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Collisional unfolding of multiprotein complexes reveals cooperative stabilization upon ligand binding

(2015) Shuai Niu et al.   PROTEIN SCIENCE

Electron transfer dissociation provides higher-order structural information of native and partially unfolded protein complexes

(2015) Frederik Lermyte et al.   PROTEOMICS

Collision Cross Sections for Structural Proteomics

(2015) Erik G. Marklund et al.   STRUCTURE

Collisional and Coulombic Unfolding of Gas-Phase Proteins: High Correlation to Their Domain Structures in Solution

(2014) Yueyang Zhong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Characterizing Intermediates Along the Transition from Polyproline I to Polyproline II Using Ion Mobility Spectrometry-Mass Spectrometry

(2014) Liuqing Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polymorphism of Oligomers of a Peptide from β-Amyloid

(2014) Johnny D. Pham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring Salt Bridge Structures of Gas-Phase Protein Ions using Multiple Stages of Electron Transfer and Collision Induced Dissociation

(2014) Zhe Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Controlling Dissociation Channels of Gas-Phase Protein Complexes Using Charge Manipulation

(2014) Sarah K. Fegan et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

A Charge Moving Algorithm for Molecular Dynamics Simulations of Gas-Phase Proteins

(2013) Sarah K. Fegan et al.   Journal of Chemical Theory and Computation

Ion Mobility Spectrometry Reveals the Mechanism of Amyloid Formation of Aβ(25–35) and Its Modulation by Inhibitors at the Molecular Level: Epigallocatechin Gallate and Scyllo-inositol

(2013) Christian Bleiholder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bovine β-Lactoglobulin Is Dimeric Under Imitative Physiological Conditions: Dissociation Equilibrium and Rate Constants over the pH Range of 2.5–7.5

(2012) Davide Mercadante et al.   BIOPHYSICAL JOURNAL

Structural and thermodynamic studies of binding saturated fatty acids to bovine β-lactoglobulin

(2012) Joanna I. Loch et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Charge-State Dependent Compaction and Dissociation of Protein Complexes: Insights from Ion Mobility and Molecular Dynamics

(2012) Zoe Hall et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mass spectrometry: come of age for structural and dynamical biology

(2011) Justin LP Benesch et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Bound Anions Differentially Stabilize Multiprotein Complexes in the Absence of Bulk Solvent

(2011) Linjie Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Electrostatic Charge Partitioning Model for the Dissociation of Protein Complexes in the Gas Phase

(2011) Stephen V. Sciuto et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Collisional activation of protein complexes: Picking up the pieces

(2008) Justin L. P. Benesch   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY