Self-assembled albumin nanoparticles induce pyroptosis for photodynamic/photothermal/immuno synergistic therapies in triple-negative breast cancer

Nrf2 silencing amplifies DNA photooxidative damage to activate the STING pathway for synergistic tumor immunotherapy

(2023) Shengjie Sun et al.   BIOMATERIALS

Glutathione-sensitive IPI-549 nanoparticles synergized with photodynamic Chlorin e6 for the treatment of breast cancer

(2022) Mengjia Yang et al.   NANOTECHNOLOGY

Homologous targeting nanoparticles for enhanced PDT against osteosarcoma HOS cells and the related molecular mechanisms

(2022) Yang Wang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Pyroptosis and pyroptosis-inducing cancer drugs

(2022) Fan Yang et al.   ACTA PHARMACOLOGICA SINICA

A facile strategy toward hierarchically porous composite scaffold for osteosarcoma ablation and massive bone defect repair

(2022) Tingxian Ling et al.   COMPOSITES PART B-ENGINEERING

Prognostic Value of Stromal Tumor-Infiltrating Lymphocytes in Young, Node-Negative, Triple-Negative Breast Cancer Patients Who Did Not Receive (neo)Adjuvant Systemic Therapy

(2022) Vincent M.T. de Jong et al.   JOURNAL OF CLINICAL ONCOLOGY

Ionizing radiation triggers the antitumor immunity by inducing GSDME-mediated pyroptosis in tumor cells

(2022) Wei Cao et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Rationally Designed Heptamethine Cyanine Photosensitizers that Amplify Tumor‐Specific Endoplasmic Reticulum Stress and Boost Antitumor Immunity

(2022) Xie Huang et al.   Small

Immune Checkpoint Inhibitors and Novel Immunotherapy Approaches for Breast Cancer

(2022) Mónica Cejuela et al.   Current Oncology Reports

Systemic Delivery of mPEG‐Masked Trispecific T‐Cell Nanoengagers in Synergy with STING Agonists Overcomes Immunotherapy Resistance in TNBC and Generates a Vaccination Effect

(2022) Ming Shen et al.   Advanced Science

Pyroptosis and respiratory diseases: A review of current knowledge

(2022) Jialiang Sun et al.   Frontiers in Immunology

Integrated manganese (III)-doped nanosystem for optimizing photothermal ablation: Amplifying hyperthermia-induced STING pathway and enhancing antitumor immunity

(2022) Jingya Xia et al.   Acta Biomaterialia

Stanene‐Based Nanosheets for β‐Elemene Delivery and Ultrasound‐Mediated Combination Cancer Therapy

(2021) Wei Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cancer Statistics, 2021

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Synergy of hypoxia relief and heat shock protein inhibition for phototherapy enhancement

(2021) Gutian Zhang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Nucleus-Targeted Photosensitizer Nanoparticles for Photothermal and Photodynamic Therapy of Breast Carcinoma

(2021) Jing Liu et al.   International Journal of Nanomedicine

Oxygen and oxaliplatin-loaded nanoparticles combined with photo-sonodynamic inducing enhanced immunogenic cell death in syngeneic mouse models of ovarian cancer

(2021) Jiao Zheng et al.   JOURNAL OF CONTROLLED RELEASE

Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells

(2021) Haein An et al.   Cell Death & Disease

Gasdermin D in pyroptosis

(2021) Brandon Burdette et al.   Acta Pharmaceutica Sinica B

Dual mitigation of immunosuppression combined with photothermal inhibition for highly effective primary tumor and metastases therapy

(2021) Ju Huang et al.   BIOMATERIALS

Randomized Phase III Postoperative Trial of Platinum-Based Chemotherapy Versus Capecitabine in Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy: ECOG-ACRIN EA1131

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Preparation of Near-Infrared/Photoacoustic Dual-Mode Imaging and Photothermal/Chemo Synergistic Theranostic Nanoparticles and Their Imaging and Treating of Hepatic Carcinoma

(2021) Yun Zhou et al.   Frontiers in Oncology

Isoorientin Attenuated the Pyroptotic Hepatocyte Damage Induced by Benzo[a]pyrene via ROS/NF-κB/NLRP3/Caspase-1 Signaling Pathway

(2021) Hao Li et al.   Antioxidants

ZnS@BSA Nanoclusters Potentiate Efficacy of Cancer Immunotherapy

(2021) Dong Cen et al.   ADVANCED MATERIALS

A multifunctional nano-therapeutic platform based on octahedral yolk-shell Au NR@CuS: Photothermal/photodynamic and targeted drug delivery tri-combined therapy for rheumatoid arthritis

(2021) Ruqi Huang et al.   BIOMATERIALS

Folic Acid Decorated Zeolitic Imidazolate Framework (ZIF-8) Loaded with Baicalin as a Nano-Drug Delivery System for Breast Cancer Therapy

(2021) Xiao Mi et al.   International Journal of Nanomedicine

Epigenetic modulation of antitumor immunity for improved cancer immunotherapy

(2021) Enyong Dai et al.   Molecular Cancer

Treatment landscape of triple-negative breast cancer — expanded options, evolving needs

(2021) Giampaolo Bianchini et al.   Nature Reviews Clinical Oncology

Cancer cell membrane-coated nanoparticles for bimodal imaging-guided photothermal therapy and docetaxel-enhanced immunotherapy against cancer

(2021) Qiaoqi Chen et al.   JOURNAL OF NANOBIOTECHNOLOGY

Regulating immune memory and reversing tumor thermotolerance through a step-by-step starving-photothermal therapy

(2021) Lihua Luo et al.   JOURNAL OF NANOBIOTECHNOLOGY

A novel nanoparticle-based theranostic agent targeting LRP-1 enhances the efficacy of neoadjuvant radiotherapy in colorectal cancer

(2020) Kyoung Jin Lee et al.   BIOMATERIALS

Role of Immunotherapy in Triple-Negative Breast Cancer

(2020) Tanya E. Keenan et al.   Journal of the National Comprehensive Cancer Network

cGAS-STING, an important pathway in cancer immunotherapy

(2020) Minlin Jiang et al.   Journal of Hematology & Oncology

Enzyme-Responsive Nanoparticles for Anti-tumor Drug Delivery

(2020) Mengqian Li et al.   Frontiers in Chemistry

Pembrolizumab and atezolizumab in triple-negative breast cancer

(2020) Dorota Kwapisz   CANCER IMMUNOLOGY IMMUNOTHERAPY

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(2020) Yang Wang et al.   Molecular Cancer

Biomineralization: An Opportunity and Challenge of Nanoparticle Drug Delivery Systems for Cancer Therapy

(2020) Weicai Wang et al.   Advanced Healthcare Materials

Improved cancer phototheranostic efficacy of hydrophobic IR780 via parenteral route by association with tetrahedral nanostructured DNA

(2020) Shuo Wang et al.   JOURNAL OF CONTROLLED RELEASE

VEGF in Signaling and Disease: Beyond Discovery and Development

(2019) Rajendra S. Apte et al.   CELL

Mitochondria-Targeted and Ultrasound-Activated Nanodroplets for Enhanced Deep-Penetration Sonodynamic Cancer Therapy

(2019) Liang Zhang et al.   ACS Applied Materials & Interfaces

The Tumor Microenvironment Innately Modulates Cancer Progression

(2019) Dominique C. Hinshaw et al.   CANCER RESEARCH

Hydrophobic IR780 loaded sericin nanomicelles for phototherapy with enhanced antitumor efficiency

(2019) Lizhi Deng et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Task-Specific Design of Immune-Augmented Nanoplatform to Enable High-Efficiency Tumor Immunotherapy

(2019) Jing Zhang et al.   ACS Applied Materials & Interfaces

Integration of immunogenic activation and immunosuppressive reversion using mitochondrial-respiration-inhibited platelet-mimicking nanoparticles

(2019) Xiaoli Mai et al.   BIOMATERIALS

Pyroptosis: A new frontier in cancer

(2019) Yuan Fang et al.   BIOMEDICINE & PHARMACOTHERAPY

Nanoparticle-mediated Immunogenic Cell Death Enables and Potentiates Cancer Immunotherapy

(2018) Xiaopin Duan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor inherent interferons: Impact on immune reactivity and immunotherapy

(2018) Natasha K. Brockwell et al.   CYTOKINE

DNA-induced liquid phase condensation of cGAS activates innate immune signaling

(2018) Mingjian Du et al.   SCIENCE

BSA-bioinspired gold nanorods loaded with immunoadjuvant for the treatment of melanoma by combined photothermal therapy and immunotherapy

(2018) Benqing Zhou et al.   Nanoscale

The Ca2+ sensor STIM1 regulates the type I interferon response by retaining the signaling adaptor STING at the endoplasmic reticulum

(2018) Sonal Srikanth et al.   NATURE IMMUNOLOGY

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Self-assembled albumin nanoparticles for combination therapy in prostate cancer

(2017) Huibo Lian et al.   International Journal of Nanomedicine

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Ki67 assessment in breast cancer: an update

(2017) Frederique Penault-Llorca et al.   PATHOLOGY

Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death

(2017) Jianjin Shi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Zinc as a Gatekeeper of Immune Function

(2017) et al.   Nutrients

An overview of triple-negative breast cancer

(2015) Pankaj Kumar et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

The pathogenic role of the inflammasome in neurodegenerative diseases

(2015) Leslie C. Freeman et al.   JOURNAL OF NEUROCHEMISTRY

Caspase target drives pyroptosis

(2015) Petr Broz   NATURE

An albumin-based theranostic nano-agent for dual-modal imaging guided photothermal therapy to inhibit lymphatic metastasis of cancer post surgery

(2014) Qian Chen et al.   BIOMATERIALS

Binding of transition metal ions to albumin: Sites, affinities and rates

(2013) Wojciech Bal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS