Transcriptional regulation of innate lymphoid cells and T cells by aryl hydrocarbon receptor

The aryl hydrocarbon receptor cell intrinsically promotes resident memory CD8+ T cell differentiation and function

(2023) Joseph W. Dean et al.   Cell Reports

HiCuT: An efficient and low input method to identify protein-directed chromatin interactions

(2022) Satish Sati et al.   PLoS Genetics

Hypoxia enhances ILC3 responses through HIF-1α-dependent mechanism

(2021) J. L. Fachi et al.   Mucosal Immunology

IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor

(2021) Yuying Liu et al.   NATURE IMMUNOLOGY

Kynurenine promotes the cytotoxicity of NK cells through aryl hydrocarbon receptor in early pregnancy

(2021) Shao-Liang Yang et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The aryl hydrocarbon receptor regulates expression of mucosal trafficking receptor GPR15

(2021) Gayathri Swaminathan et al.   Mucosal Immunology

AHR Regulates NK Cell Migration via ASB2–Mediated Ubiquitination of Filamin A

(2021) June Ho Shin et al.   Frontiers in Immunology

Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells

(2021) Ilkka Liikanen et al.   JOURNAL OF CLINICAL INVESTIGATION

AHR in the intestinal microenvironment: safeguarding barrier function

(2021) Brigitta Stockinger et al.   Nature Reviews Gastroenterology & Hepatology

Acute Myeloid Leukemia Alters Group 1 Innate Lymphoid Cell Differentiation from a Common Precursor

(2021) Matthew R. Lordo et al.   JOURNAL OF IMMUNOLOGY

Tissue signals imprint Aiolos expression in ILC2s to modulate type 2 immunity

(2021) Jinxin Qiu et al.   Mucosal Immunology

Regulatory T Cells and Human Disease

(2020) Shimon Sakaguchi et al.   Annual Review of Immunology

IL6 Induces an IL22+ CD8+ T-cell Subset with Potent Antitumor Function

(2020) Michael St. Paul et al.   Cancer Immunology Research

The Ah Receptor: Adaptive Metabolism, Ligand Diversity, and the Xenokine Model

(2020) Mele N. Avilla et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Ahr-Foxp3-RORγt axis controls gut homing of CD4+ T cells by regulating GPR15

(2020) Lifeng Xiong et al.   Science Immunology

Leptin Promoted IL-17 Production from ILC2s in Allergic Rhinitis

(2020) Yanhui Wen et al.   MEDIATORS OF INFLAMMATION

Aryl hydrocarbon receptor activation modulates γδ intestinal intraepithelial lymphocytes and protects against ischemia/reperfusion injury in the murine small intestine

(2019) Zhicao Zhang et al.   Molecular Medicine Reports

Hobit- and Blimp-1-driven CD4+ tissue-resident memory T cells control chronic intestinal inflammation

(2019) Sebastian Zundler et al.   NATURE IMMUNOLOGY

ILC3s integrate glycolysis and mitochondrial production of reactive oxygen species to fulfill activation demands

(2019) Blanda Di Luccia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ikaros Zinc Finger Transcription Factors: Regulators of Cytokine Signaling Pathways and CD4+ T Helper Cell Differentiation

(2019) Michael D. Powell et al.   Frontiers in Immunology

Indoleamine-2,3-Dioxygenase in Thyroid Cancer Cells Suppresses Natural Killer Cell Function by Inhibiting NKG2D and NKp46 Expression via STAT Signaling Pathways

(2019) Arum Park et al.   Journal of Clinical Medicine

Tumor-Repopulating Cells Induce PD-1 Expression in CD8 + T Cells by Transferring Kynurenine and AhR Activation

(2018) Yuying Liu et al.   CANCER CELL

The aryl hydrocarbon receptor modulates the function of human CD56bright NK cells

(2018) Uriel Y. Moreno-Nieves et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulation of the Immune Response by the Aryl Hydrocarbon Receptor

(2018) Cristina Gutiérrez-Vázquez et al.   IMMUNITY

IL-17–producing ST2 + group 2 innate lymphoid cells play a pathogenic role in lung inflammation

(2018) Ting Cai et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

AHR signaling in the development and function of intestinal immune cells and beyond

(2018) Luisa Cervantes-Barragan et al.   Seminars in Immunopathology

The Murine Natural Cytotoxic Receptor NKp46/NCR1 Controls TRAIL Protein Expression in NK Cells and ILC1s

(2018) Sam Sheppard et al.   Cell Reports

Regulation of Innate Lymphoid Cells by Aryl Hydrocarbon Receptor

(2018) Shiyang Li et al.   Frontiers in Immunology

Innate Lymphoid Cells: 10 Years On

(2018) Eric Vivier et al.   CELL

Aryl Hydrocarbon Receptor Signaling Cell Intrinsically Inhibits Intestinal Group 2 Innate Lymphoid Cell Function

(2018) Shiyang Li et al.   IMMUNITY

An endogenous aryl hydrocarbon receptor ligand enhances de novo generation of regulatory T cells in humans

(2018) Imen Zamali et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Single-pot, solid-phase-enhanced sample preparation for proteomics experiments

(2018) Christopher S. Hughes et al.   Nature Protocols

Feedback control of AHR signalling regulates intestinal immunity

(2017) Chris Schiering et al.   NATURE

TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation

(2017) Allison K Ehrlich et al.   TOXICOLOGICAL SCIENCES

The Aryl Hydrocarbon Receptor Preferentially Marks and Promotes Gut Regulatory T Cells

(2017) Jian Ye et al.   Cell Reports

An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites

(2017) Peter J Skene et al.   eLife

A tightly regulated IL-22 response maintains immune functions and homeostasis in systemic viral infection

(2017) Panpan Yi et al.   Scientific Reports

AhR modulates the IL-22-producing cell proliferation/recruitment in imiquimod-induced psoriasis mouse model

(2016) Perrine M. Cochez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ikaros Inhibits Group 3 Innate Lymphoid Cell Development and Function by Suppressing the Aryl Hydrocarbon Receptor Pathway

(2016) Shiyang Li et al.   IMMUNITY

The aryl hydrocarbon receptor is required for the maintenance of liver-resident natural killer cells

(2016) Luhua H. Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis

(2016) Danay Cibrian et al.   NATURE IMMUNOLOGY

HiChIP: efficient and sensitive analysis of protein-directed genome architecture

(2016) Maxwell R Mumbach et al.   NATURE METHODS

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

AHR Function in Lymphocytes: Emerging Concepts

(2016) Liang Zhou   TRENDS IN IMMUNOLOGY

Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α

(2015) Ivan D Mascanfroni et al.   NATURE MEDICINE

Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4+ T cells

(2015) M. R. Hepworth et al.   SCIENCE

Differentiation of Type 1 ILCs from a Common Progenitor to All Helper-like Innate Lymphoid Cell Lineages

(2014) Christoph S.N. Klose et al.   CELL

Human RORγt+CD34+ Cells Are Lineage-Specified Progenitors of Group 3 RORγt+ Innate Lymphoid Cells

(2014) Elisa Montaldo et al.   IMMUNITY

Induction of Innate Lymphoid Cell-Derived Interleukin-22 by the Transcription Factor STAT3 Mediates Protection against Intestinal Infection

(2014) Xiaohuan Guo et al.   IMMUNITY

Development, Differentiation, and Diversity of Innate Lymphoid Cells

(2014) Andreas Diefenbach et al.   IMMUNITY

Restriction of IL-22–Producing T Cell Responses and Differential Regulation of Regulatory T Cell Compartments by Zinc Finger Transcription Factor Ikaros

(2014) Jennifer J. Heller et al.   JOURNAL OF IMMUNOLOGY

The Aryl Hydrocarbon Receptor Promotes IL-10 Production by NK Cells

(2014) S. Wagage et al.   JOURNAL OF IMMUNOLOGY

Persistence of skin-resident memory T cells within an epidermal niche

(2014) A. Zaid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-21 induces IL-22 production in CD4+ T cells

(2014) Ada Yeste et al.   Nature Communications

The Transcription Factor AHR Prevents the Differentiation of a Stage 3 Innate Lymphoid Cell Subset to Natural Killer Cells

(2014) Tiffany Hughes et al.   Cell Reports

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Group 3 Innate Lymphoid Cells Inhibit T-Cell-Mediated Intestinal Inflammation through Aryl Hydrocarbon Receptor Signaling and Regulation of Microflora

(2013) Ju Qiu et al.   IMMUNITY

Ikaros Sets the Potential for Th17 Lineage Gene Expression through Effects on Chromatin State in Early T Cell Development

(2013) Larry Y. Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of natural killer cell antitumor activity by the aryl hydrocarbon receptor

(2013) J. H. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription of Il17 and Il17f Is Controlled by Conserved Noncoding Sequence 2

(2012) Xiaohu Wang et al.   IMMUNITY

Th22 Cells Are an Important Source of IL-22 for Host Protection against Enteropathogenic Bacteria

(2012) Rajatava Basu et al.   IMMUNITY

Aiolos promotes TH17 differentiation by directly silencing Il2 expression

(2012) Francisco J Quintana et al.   NATURE IMMUNOLOGY

Aryl Hydrocarbon Receptor-Mediated Perturbations in Gene Expression during Early Stages of CD4+ T-cell Differentiation

(2012) Diana Rohlman et al.   Frontiers in Immunology

Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation

(2011) Ying Li et al.   CELL

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

(2011) Ju Qiu et al.   IMMUNITY

Aryl Hydrocarbon Receptor Is Critical for Homeostasis of Invariant    T Cells in the Murine Epidermis

(2011) S. Kadow et al.   JOURNAL OF IMMUNOLOGY

Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells

(2011) Sascha Rutz et al.   NATURE IMMUNOLOGY

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

(2011) Jacob S Lee et al.   NATURE IMMUNOLOGY

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

(2011) Wei Liao et al.   NATURE IMMUNOLOGY

Activation of Aryl Hydrocarbon Receptor (AhR) Leads to Reciprocal Epigenetic Regulation of FoxP3 and IL-17 Expression and Amelioration of Experimental Colitis

(2011) Narendra P. Singh et al.   PLoS One

Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lymphoid Follicles

(2011) E. A. Kiss et al.   SCIENCE

Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells

(2010) Jean-Marie Ramirez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-1β Selectively Expands and Sustains Interleukin-22+ Immature Human Natural Killer Cells in Secondary Lymphoid Tissue

(2010) Tiffany Hughes et al.   IMMUNITY

Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis

(2010) Lydia Durant et al.   IMMUNITY

γδ T cells protect against lung fibrosis via IL-22

(2010) Philip L. Simonian et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells

(2010) J. D. Mezrich et al.   JOURNAL OF IMMUNOLOGY

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell–like and Foxp3+ regulatory T cells

(2010) Roopali Gandhi et al.   NATURE IMMUNOLOGY

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

γδ T Cells and the Lymphoid Stress-Surveillance Response

(2009) Adrian C. Hayday   IMMUNITY

Blimp-1 Transcription Factor Is Required for the Differentiation of Effector CD8+ T Cells and Memory Responses

(2009) Axel Kallies et al.   IMMUNITY

Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from TH-17, TH1 and TH2 cells

(2009) Sara Trifari et al.   NATURE IMMUNOLOGY

Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells

(2009) Thomas Duhen et al.   NATURE IMMUNOLOGY

The STAT3 NH2-terminal Domain Stabilizes Enhanceosome Assembly by Interacting with the p300 Bromodomain

(2008) Tieying Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

(2008) Marc Veldhoen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells

(2008) A. Kimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA