The applications of animal models in phage therapy: An update

Considerations for the Use of Phage Therapy in Clinical Practice

(2022) Gina A. Suh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phage Revolution Against Multidrug-Resistant Clinical Pathogens in Southeast Asia

(2022) Mark B. Carascal et al.   Frontiers in Microbiology

A Multiwell-Plate Caenorhabditis elegans Assay for Assessing the Therapeutic Potential of Bacteriophages against Clinical Pathogens

(2022) Prasanth Manohar et al.   Microbiology Spectrum

Host and pathogen response to bacteriophage engineered against Mycobacterium abscessus lung infection

(2022) Jerry A. Nick et al.   CELL

Safety and efficacy of phage therapy in difficult-to-treat infections: a systematic review

(2022) Saartje Uyttebroek et al.   LANCET INFECTIOUS DISEASES

Limitations of Phage Therapy and Corresponding Optimization Strategies: A Review

(2022) Jiaxi Lin et al.   MOLECULES

Multidrug-resistant enteric bacteria in Nigeria and potential use of bacteriophages as biocontrol

(2022) Greater Kayode Oyejobi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection

(2022) Jessica S. Little et al.   Nature Communications

Editorial: Bacteriophages and Their Lytic Enzymes as Alternative Antibacterial Therapies in the Age of Antibiotic Resistance

(2022) Carlos São-José et al.   Frontiers in Microbiology

Immunogenicity of Endolysin PlyC

(2022) Marek Adam Harhala et al.   Antibiotics-Basel

Antibiotics targeting bacterial protein synthesis reduce the lytic activity of bacteriophages

(2022) Medhavi Vashisth et al.   VIRUS RESEARCH

Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosa infection to allow liver transplantation in a toddler

(2022) Brieuc Van Nieuwenhuyse et al.   Nature Communications

The Safety and Efficacy of Phage Therapy: A Systematic Review of Clinical and Safety Trials

(2022) Helen J. Stacey et al.   Antibiotics-Basel

Clinical Experience of Personalized Phage Therapy Against Carbapenem-Resistant Acinetobacter baumannii Lung Infection in a Patient With Chronic Obstructive Pulmonary Disease

(2021) Xin Tan et al.   Frontiers in Cellular and Infection Microbiology

A Novel Acinetobacter baumannii Bacteriophage Endolysin LysAB54 With High Antibacterial Activity Against Multiple Gram-Negative Microbes

(2021) Fazal Mehmood Khan et al.   Frontiers in Cellular and Infection Microbiology

Phage-Encoded Endolysins

(2021) Fatma Abdelrahman et al.   Antibiotics-Basel

Bacteriophage and Endolysin Encapsulation Systems: A Promising Strategy to Improve Therapeutic Outcomes

(2021) Vijay Singh Gondil et al.   Frontiers in Pharmacology

A Highly Active Chimeric Lysin with a Calcium-Enhanced Bactericidal Activity against Staphylococcus aureus In Vitro and In Vivo

(2021) Xiaohong Li et al.   Antibiotics-Basel

Phage Therapy for Antibiotic-Resistant Bacterial Infections

(2021) Graham F. Hatfull et al.   Annual Review of Medicine

Immune Response to Therapeutic Staphylococcal Bacteriophages in Mammals: Kinetics of Induction, Immunogenic Structural Proteins, Natural and Induced Antibodies

(2021) Zuzanna Kaźmierczak et al.   Frontiers in Immunology

Intrinsic Antimicrobial Peptide Facilitates a New Broad-Spectrum Lysin LysP53 to Kill Acinetobacter baumannii In Vitro and in a Mouse Burn Infection Model

(2021) Changchang Li et al.   ACS Infectious Diseases

T7 Phage as an Emerging Nanobiomaterial with Genetically Tunable Target Specificity

(2021) Hui Yue et al.   Advanced Science

Construction and characterization of a chimeric lysin ClyV with improved bactericidal activity against Streptococcus agalactiae in vitro and in vivo

(2020) Li Huang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Phage therapy efficacy: a review of the last 10 years of preclinical studies

(2020) Luís D. R. Melo et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Characterization of Pseudomonas lytic phages and their application as a cocktail with antibiotics in controlling Pseudomonas aeruginosa

(2020) Soo Peng Ong et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

TSPphg Lysin from the Extremophilic Thermus Bacteriophage TSP4 as a Potential Antimicrobial Agent against Both Gram-Negative and Gram-Positive Pathogenic Bacteria

(2020) Feng Wang et al.   Viruses-Basel

Phage Lytic Protein LysRODI Prevents Staphylococcal Mastitis in Mice

(2020) Diana Gutiérrez et al.   Frontiers in Microbiology

Antimicrobial activity of LysSS, a novel phage endolysin, against Acinetobacter baumannii and Pseudomonas aeruginosa

(2020) Shukho Kim et al.   Journal of Global Antimicrobial Resistance

Treat phage like living antibiotics

(2020) Robert T. Schooley et al.   Nature Microbiology

Safety of bacteriophage therapy in severe Staphylococcus aureus infection

(2020) Aleksandra Petrovic Fabijan et al.   Nature Microbiology

Effect of the Lysin, Exebacase, on Cardiac Vegetation Progression in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus (MRSA) Endocarditis as Determined by Echocardiography

(2020) Sonia U. Shah et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

RLP, a bacteriophage of the family Podoviridae, rescues mice from bacteremia caused by multi-drug-resistant Pseudomonas aeruginosa

(2020) Iqbal Ahmad Alvi et al.   ARCHIVES OF VIROLOGY

Animal Models to Translate Phage Therapy to Human Medicine

(2020) Alessia Brix et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In vitro and in vivo efficacy of combinations of colistin and different endolysins against clinical strains of multi-drug resistant pathogens

(2020) Lucia Blasco et al.   Scientific Reports

Standardized bacteriophage purification for personalized phage therapy

(2020) Tiffany Luong et al.   Nature Protocols

Intravesical bacteriophages for treating urinary tract infections in patients undergoing transurethral resection of the prostate: a randomised, placebo-controlled, double-blind clinical trial

(2020) Lorenz Leitner et al.   LANCET INFECTIOUS DISEASES

Lessons Learned From the First 10 Consecutive Cases of Intravenous Bacteriophage Therapy to Treat Multidrug-Resistant Bacterial Infections at a Single Center in the United States

(2020) Saima Aslam et al.   Open Forum Infectious Diseases

Population Dynamics between Erwinia amylovora, Pantoea agglomerans and Bacteriophages: Exploiting Synergy and Competition to Improve Phage Cocktail Efficacy

(2020) Steven Gayder et al.   Microorganisms

Encapsulation and Delivery of Therapeutic Phages

(2020) Belinda Loh et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Enhancing phage therapy through synthetic biology and genome engineering

(2020) Bryan R Lenneman et al.   CURRENT OPINION IN BIOTECHNOLOGY

Bacteriophage Interactions with Mammalian Tissue: Therapeutic Applications

(2019) Haein Huh et al.   ADVANCED DRUG DELIVERY REVIEWS

ClyJ, a novel pneumococcal chimeric lysin with a CHAP catalytic domain

(2019) Hang Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Isolation of a T7-Like Lytic Pasteurella Bacteriophage vB_PmuP_PHB01 and Its Potential Use in Therapy against Pasteurella multocida Infections

(2019) Yibao Chen et al.   Viruses-Basel

Design and Preclinical Development of a Phage Product for the Treatment of Antibiotic-Resistant Staphylococcus aureus Infections

(2019) Susan Lehman et al.   Viruses-Basel

A Novel Phage PD-6A3, and Its Endolysin Ply6A3, With Extended Lytic Activity Against Acinetobacter baumannii

(2019) Minle Wu et al.   Frontiers in Microbiology

The Ability of Lytic Staphylococcal Podovirus vB_SauP_phiAGO1.3 to Coexist in Equilibrium With Its Host Facilitates the Selection of Host Mutants of Attenuated Virulence but Does Not Preclude the Phage Antistaphylococcal Activity in a Nematode Infection Model

(2019) Aleksandra Głowacka-Rutkowska et al.   Frontiers in Microbiology

Fighting Pathogenic Bacteria on Two Fronts: Phages and Antibiotics as Combined Strategy

(2019) Thaysa Leite Tagliaferri et al.   Frontiers in Cellular and Infection Microbiology

Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model

(2019) Marco Cafora et al.   Scientific Reports

Determinants of Phage Host Range in Staphylococcus Species

(2019) Abraham G. Moller et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Isolation of phage lysins that effectively kill Pseudomonas aeruginosa in mouse models of lung and skin infection

(2019) Assaf Raz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Lysocins: Bioengineered Antimicrobials That Deliver Lysins across the Outer Membrane of Gram-Negative Bacteria

(2019) Ryan D. Heselpoth et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Peculiarities of Staphylococcus aureus phages and their possible application in phage therapy

(2019) Aa Haeruman Azam et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Engineered bacteriophages for treatment of a patient with a disseminated drug-resistant Mycobacterium abscessus

(2019) Rebekah M. Dedrick et al.   NATURE MEDICINE

Phage Therapy Regulation: From Night to Dawn

(2019) Alan Fauconnier   Viruses-Basel

Biodistribution of Liposome-Encapsulated Bacteriophages and Their Transcytosis During Oral Phage Therapy

(2019) Jennifer Otero et al.   Frontiers in Microbiology

Efficacy of Newly Isolated and Highly Potent Bacteriophages in a Mouse Model of XDRAB Bacteremia

(2019) Lika Leshkasheli et al.   Journal of Global Antimicrobial Resistance

Exebacase in Addition to Daptomycin is More Active than Daptomycin or Exebacase Alone in Methicillin-Resistant Staphylococcus aureus Osteomyelitis in Rats

(2019) Melissa J. Karau et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Complete genome analysis of the novel Enterococcus faecalis phage vB_EfaS_AL3

(2019) Yuyu Yuan et al.   ARCHIVES OF VIROLOGY

Evaluation of phage therapy in the treatment of Staphylococcus aureus-induced mastitis in mice

(2019) Huijun Geng et al.   FOLIA MICROBIOLOGICA

Phages in a thermoreversible sustained-release formulation targeting E. faecalis in vitro and in vivo

(2019) Mor Shlezinger et al.   PLoS One

Efficacy and safety assessment of two enterococci phages in an in vitro biofilm wound model

(2019) Luís D. R. Melo et al.   Scientific Reports

Synergy Between Two Chimeric Lysins to Kill Streptococcus pneumoniae

(2019) Roberto Vázquez et al.   Frontiers in Microbiology

Safety and Tolerability of Bacteriophage Therapy for Chronic Rhinosinusitis Due to Staphylococcus aureus

(2019) Mian Li Ooi et al.   JAMA Otolaryngology-Head & Neck Surgery

The Bacteriophages of Streptococcus pyogenes

(2019) W. Michael McShan et al.   Microbiology Spectrum

Bacteriophages as adjuvant to antibiotics for the treatment of periprosthetic joint infection caused by multidrug-resistant Pseudomonas aeruginosa

(2019) Tamta Tkhilaishvili et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of novel bacteriophages with therapeutic potential targeting Enterococcus faecalis

(2019) M Al-Zubidi et al.   INFECTION AND IMMUNITY

Application of the Phage Lysin Ply5218 in the Treatment of Streptococcus suis Infection in Piglets

(2019) Zhaofei Wang et al.   Viruses-Basel

Therapeutic Potential of an Endolysin Derived from Kayvirus S25-3 for Staphylococcal Impetigo

(2019) Ichiro Imanishi et al.   Viruses-Basel

Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection

(2019) Alexandra G. Fraga et al.   PLoS Neglected Tropical Diseases

Genomic and Ecogenomic Characterization of Proteus mirabilis Bacteriophages

(2019) Diana R. Alves et al.   Frontiers in Microbiology

Linker editing of pneumococcal lysin ClyJ conveys improved bactericidal activity

(2019) Hang Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Silviavirus phage ɸMR003 displays a broad host range against methicillin-resistant Staphylococcus aureus of human origin

(2019) Chanthol Peng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Endolysins as emerging alternative therapeutic agent to counter drug resistant infections.

(2019) Vijay Singh Gondil et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Exploring the whole standard operating procedure for phage therapy in clinical practice

(2019) Zelin Cui et al.   Journal of Translational Medicine

A novel wound dressing consisting of PVA-SA hybrid hydrogel membrane for topical delivery of bacteriophages and antibiotics

(2019) Prabhjot Kaur et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

An experimental mouse model for phage therapy of bacterial pathogens causing bacteremia

(2019) Sadeq Abdulridha Gatea Kaabi et al.   MICROBIAL PATHOGENESIS

Bacteriophage Therapeutics: A Primer for Clinicians on Phage‐Antibiotic Combinations

(2019) Taylor Morrisette et al.   PHARMACOTHERAPY

Evaluation of bacteriophage as an adjunct therapy for treatment of peri-prosthetic joint infection caused by Staphylococcus aureus

(2019) Jodie L. Morris et al.   PLoS One

The Novel Enterococcus Phage vB_EfaS_HEf13 Has Broad Lytic Activity Against Clinical Isolates of Enterococcus faecalis

(2019) Dongwook Lee et al.   Frontiers in Microbiology

Design of a Broad-Range Bacteriophage Cocktail That Reduces Pseudomonas aeruginosa Biofilms and Treats Acute Infections in Two Animal Models

(2018) Francesca Forti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chemotherapy with Phage Lysins Reduces Pneumococcal Colonization of the Respiratory Tract

(2018) Bruno Corsini et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of a novel phage infecting the pathogenic multidrug-resistant Bacillus cereus and functional analysis of its endolysin

(2018) Qin Peng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Combined bacteriophages and antibiotics as an efficient therapy against VRE Enterococcus faecalis in a mouse model

(2018) Daniel Gelman et al.   RESEARCH IN MICROBIOLOGY

An Ointment Consisting of the Phage Lysin LysGH15 and Apigenin for Decolonization of Methicillin-Resistant Staphylococcus aureus from Skin Wounds

(2018) Mengjun Cheng et al.   Viruses-Basel

The Magistral Phage

(2018) Jean-Paul Pirnay et al.   Viruses-Basel

Development of Phage Lysins as Novel Therapeutics: A Historical Perspective

(2018) Vincent Fischetti   Viruses-Basel

Resistance Development to Bacteriophages Occurring during Bacteriophage Therapy

(2018) Frank Oechslin   Viruses-Basel

Activity of the Chimeric Lysin ClyR against Common Gram-Positive Oral Microbes and Its Anticaries Efficacy in Rat Models

(2018) Jingjing Xu et al.   Viruses-Basel

Kinetics of Targeted Phage Rescue in a Mouse Model of Systemic Escherichia coli K1

(2018) György Schneider et al.   Biomed Research International

Two New Lytic Bacteriophages of the Myoviridae Family Against Carbapenem-Resistant Acinetobacter baumannii

(2018) Weilong Zhou et al.   Frontiers in Microbiology

Defeating Antibiotic- and Phage-Resistant Enterococcus faecalis Using a Phage Cocktail in Vitro and in a Clot Model

(2018) Leron Khalifa et al.   Frontiers in Microbiology

Phage Therapy as a Promising New Treatment for Lung Infection Caused by Carbapenem-Resistant Acinetobacter baumannii in Mice

(2018) Yunfen Hua et al.   Frontiers in Microbiology

The therapeutic potential of bacteriophages targeting gram-negative bacteria using Galleria mellonella infection model

(2018) Prasanth Manohar et al.   BMC MICROBIOLOGY

Bactericidal synergism between antibiotics and phage endolysin Cpl-711 to kill multidrug-resistant pneumococcus

(2018) Patricia Letrado et al.   Future Microbiology

Bacteriophage for Gastrointestinal Health (PHAGE) Study: Evaluating the Safety and Tolerability of Supplemental Bacteriophage Consumption

(2018) Melinda Gindin et al.   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Efficacy and tolerability of a cocktail of bacteriophages to treat burn wounds infected by Pseudomonas aeruginosa (PhagoBurn): a randomised, controlled, double-blind phase 1/2 trial

(2018) Patrick Jault et al.   LANCET INFECTIOUS DISEASES

Safety Studies of Pneumococcal Endolysins Cpl-1 and Pal

(2018) Marek Harhala et al.   Viruses-Basel

Interactions between Bacteriophage, Bacteria, and the Mammalian Immune System

(2018) Jonas Van Belleghem et al.   Viruses-Basel

Bacteriophage Therapy: Clinical Trials and Regulatory Hurdles

(2018) Lucy L. Furfaro et al.   Frontiers in Cellular and Infection Microbiology

Improved Biodistribution and Extended Serum Half-Life of a Bacteriophage Endolysin by Albumin Binding Domain Fusion

(2018) Johan Seijsing et al.   Frontiers in Microbiology

The distribution of carbapenem- and colistin-resistance in Gram-negative bacteria from the Tamil Nadu region in India

(2017) Prasanth Manohar et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Broad-range lytic bacteriophages that kill Staphylococcus aureus local field strains

(2017) Virginia Abatángelo et al.   PLoS One

Phage therapy is highly effective against chronic lung infections with Pseudomonas aeruginosa

(2017) Elaine M Waters et al.   THORAX

Bacteriophage therapy to combat bacterial infections in poultry

(2017) Andrzej Wernicki et al.   Virology Journal

A cocktail of three virulent bacteriophages prevents Vibrio cholerae infection in animal models

(2017) Minmin Yen et al.   Nature Communications

Activity of Bacteriophages in Removing Biofilms of Pseudomonas aeruginosa Isolates from Chronic Rhinosinusitis Patients

(2017) Stephanie A. Fong et al.   Frontiers in Cellular and Infection Microbiology

Global Survey and Genome Exploration of Bacteriophages Infecting the Lactic Acid Bacterium Streptococcus thermophilus

(2017) Brian McDonnell et al.   Frontiers in Microbiology

A novel chimeric lysin with robust antibacterial activity against planktonic and biofilm methicillin-resistant Staphylococcus aureus

(2017) Hang Yang et al.   Scientific Reports

Microencapsulation with alginate/CaCO3: A strategy for improved phage therapy

(2017) Joan Colom et al.   Scientific Reports

Bacteriophages as potential new mammalian pathogens

(2017) George V. Tetz et al.   Scientific Reports

Highly potent antimicrobial modified peptides derived from the Acinetobacter baumannii phage endolysin LysAB2

(2017) Shih-Yi Peng et al.   Scientific Reports

Personalized Therapeutic Cocktail of Wild Environmental Phages Rescues Mice from Acinetobacter baumannii Wound Infections

(2016) James M. Regeimbal et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Delivering phage therapy per os: benefits and barriers

(2016) Susan Zelasko et al.   Expert Review of Anti-Infective Therapy

Safety of using Escherichia coli bacteriophages as a sanitizing agent based on inflammatory responses in rats

(2016) Ji-Yeon Hwang et al.   FOOD SCIENCE AND BIOTECHNOLOGY

Phage therapy of staphylococcal chronic osteomyelitis in experimental animal model

(2016) Gopal Nath et al.   INDIAN JOURNAL OF MEDICAL RESEARCH

Bacteriophage therapy: a regulatory perspective

(2016) Eric Pelfrene et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Synergistic interaction between phage therapy and antibiotics clears Pseudomonas aeruginosa infection in endocarditis and reduces virulence

(2016) Frank Oechslin et al.   JOURNAL OF INFECTIOUS DISEASES

Efficacy of lytic Staphylococcus aureus bacteriophage against multidrug-resistant Staphylococcus aureus in mice

(2016) Joseph Michael Ochieng' Oduor et al.   Journal of Infection in Developing Countries

Antibody Production in Response to Staphylococcal MS-1 Phage Cocktail in Patients Undergoing Phage Therapy

(2016) Maciej Żaczek et al.   Frontiers in Microbiology

Commentary: Phage Therapy of Staphylococcal Chronic Osteomyelitis in Experimental Animal Model

(2016) Stephen T. Abedon   Frontiers in Microbiology

Prophylactic Bacteriophage Administration More Effective than Post-infection Administration in Reducing Salmonella enterica serovar Enteritidis Shedding in Quail

(2016) Mosab Ahmadi et al.   Frontiers in Microbiology

Characterization and Testing the Efficiency of Acinetobacter baumannii Phage vB-GEC_Ab-M-G7 as an Antibacterial Agent

(2016) Ia Kusradze et al.   Frontiers in Microbiology

‘Get in Early’; Biofilm and Wax Moth (Galleria mellonella) Models Reveal New Insights into the Therapeutic Potential of Clostridium difficile Bacteriophages

(2016) Janet Y. Nale et al.   Frontiers in Microbiology

Phage Therapy: Combating Infections with Potential for Evolving from Merely a Treatment for Complications to Targeting Diseases

(2016) Andrzej Górski et al.   Frontiers in Microbiology

Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh

(2016) Shafiqul Alam Sarker et al.   EBioMedicine

Bacteriophage Combinations Significantly Reduce Clostridium difficile GrowthIn Vitroand ProliferationIn Vivo

(2015) Janet Y. Nale et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antipseudomonal Bacteriophage Reduces Infective Burden and Inflammatory Response in Murine Lung

(2015) Rishi Pabary et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Liposome-Encapsulated Bacteriophages for Enhanced Oral Phage Therapy against Salmonella spp.

(2015) Joan Colom et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The CRISPR-Cas immune system: Biology, mechanisms and applications

(2015) Devashish Rath et al.   BIOCHIMIE

A genomic approach to understand interactions between Streptococcus pneumoniae and its bacteriophages

(2015) Philippe Leprohon et al.   BMC GENOMICS

Treatment of Highly Virulent Extraintestinal Pathogenic Escherichia coli Pneumonia With Bacteriophages*

(2015) Nicolas Dufour et al.   CRITICAL CARE MEDICINE

Advances in phage display technology for drug discovery

(2015) Kobra Omidfar et al.   Expert Opinion on Drug Discovery

Evaluation of the Efficacy of a Bacteriophage in the Treatment of Pneumonia Induced by Multidrug ResistanceKlebsiella pneumoniaein Mice

(2015) Fang Cao et al.   Biomed Research International

A chimeolysin with extended-spectrum streptococcal host range found by an induced lysis-based rapid screening method

(2015) Hang Yang et al.   Scientific Reports

Preclinical Safety Evaluation of Intravenously Administered SAL200 Containing the Recombinant Phage Endolysin SAL-1 as a Pharmaceutical Ingredient

(2014) Soo Youn Jun et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization and Stability Analysis of Biopolymeric Matrices Designed for Phage-Controlled Release

(2014) Cecilia Dini et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Call for a Dedicated European Legal Framework for Bacteriophage Therapy

(2014) Gilbert Verbeken et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Application of ΦSP-1 and ΦSP-3 as a therapeutic strategy againstSalmonellaEnteritidis infection usingCaenorhabditis elegansas model organism

(2014) Jeena Augustine et al.   FEMS MICROBIOLOGY LETTERS

Observation of inflammatory responses in mice orally fed with bacteriophage T7

(2014) K. Park et al.   JOURNAL OF APPLIED MICROBIOLOGY

Immunogenicity Studies of Proteins Forming the T4 Phage Head Surface

(2014) K. D browska et al.   JOURNAL OF VIROLOGY

Experimental phage therapy against lethal lung-derived septicemia caused by Staphylococcus aureus in mice

(2014) Iyo Takemura-Uchiyama et al.   MICROBES AND INFECTION

Phage Neutralization by Sera of Patients Receiving Phage Therapy

(2014) Marzanna Łusiak-Szelachowska et al.   VIRAL IMMUNOLOGY

Experimental Protection of Diabetic Mice against LethalP. aeruginosaInfection by Bacteriophage

(2014) Nagaveni Shivshetty et al.   Biomed Research International

Bacteriophage therapy of venous leg ulcers in humans: results of a phase I safety trial

(2014) D.D. Rhoads et al.   Journal of Wound Care

Novel Chimeric Lysin with High-Level Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus In Vitro andIn Vivo

(2013) Hang Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization and genome sequencing of a novel bacteriophage infecting Streptococcus agalactiae with high similarity to a phage from Streptococcus pyogenes

(2013) Qinqin Bai et al.   ARCHIVES OF VIROLOGY

T4 Phage and Its Head Surface Proteins Do Not Stimulate Inflammatory Mediator Production

(2013) Paulina Miernikiewicz et al.   PLoS One

Hurdles in bacteriophage therapy: Deconstructing the parameters

(2013) Jessica Tsonos et al.   VETERINARY MICROBIOLOGY

Efficacy of Bacteriophage Therapy in Experimental Sepsis and Meningitis Caused by a Clone O25b:H4-ST131 Escherichia coli Strain Producing CTX-M-15

(2012) Flavie Pouillot et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Biology and Genome Sequence of Streptococcus mutans Phage M102AD

(2012) Allan L. Delisle et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Pseudomonas aeruginosa Keratitis in Mice: Effects of Topical Bacteriophage KPP12 Administration

(2012) Ken Fukuda et al.   PLoS One

Bacteriophages and their Implications on Future Biotechnology: A Review

(2012) Irshad UL Haq et al.   Virology Journal

The next generation of bacteriophage therapy

(2011) Timothy K Lu et al.   CURRENT OPINION IN MICROBIOLOGY

CRISPR/Cas System and Its Role in Phage-Bacteria Interactions

(2010) Hélène Deveau et al.   Annual Review of Microbiology

Wide Host Range and Strong Lytic Activity ofStaphylococcusaureusLytic Phage Stau2

(2010) Sue-Er Hsieh et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Phage Therapy for Plant Disease Control

(2010) B. Balogh et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Designing Phage Therapeutics

(2010) Lawrence Goodridge   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Phage Therapy Pharmacology

(2010) Stephen Abedon et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Phage Choice, Isolation, and Preparation for Phage Therapy

(2010) Jason Gill et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Phage Therapy in Clinical Practice: Treatment of Human Infections

(2010) Elizabeth Kutter et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Synergy between the phage endolysin LysH5 and nisin to kill Staphylococcus aureus in pasteurized milk

(2010) Pilar García et al.   INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY

Bacteriophages Can Treat and PreventPseudomonas aeruginosaLung Infections

(2010) Laurent Debarbieux et al.   JOURNAL OF INFECTIOUS DISEASES

Bacteriophage versus antimicrobial agents for the treatment of murine burn wound infection caused by Klebsiella pneumoniae B5055

(2010) S. Kumari et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Bacteriophage resistance mechanisms

(2010) Simon J. Labrie et al.   NATURE REVIEWS MICROBIOLOGY

Orally Administered P22 Phage Tailspike Protein Reduces Salmonella Colonization in Chickens: Prospects of a Novel Therapy against Bacterial Infections

(2010) Shakeeba Waseh et al.   PLoS One

Experimental Bacteriophage Therapy Increases Survival of Galleria mellonella Larvae Infected with Clinically Relevant Strains of the Burkholderia cepacia Complex

(2009) K. D. Seed et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antibacterial Efficacy of Phages against Pseudomonas aeruginosa Infections in Mice and Drosophila melanogaster

(2009) Y.-J. Heo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistantPseudomonas aeruginosa; a preliminary report of efficacy

(2009) A. Wright et al.   CLINICAL OTOLARYNGOLOGY

Efficacy of Bacteriophage Therapy in a Model ofBurkholderia cenocepaciaPulmonary Infection

(2009) Lisa A. Carmody et al.   JOURNAL OF INFECTIOUS DISEASES

Microencapsulation of Bacteriophage Felix O1 into Chitosan-Alginate Microspheres for Oral Delivery

(2008) Y. Ma et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

In Silico and In Vivo Evaluation of Bacteriophage  EF24C, a Candidate for Treatment of Enterococcus faecalis Infections

(2008) J. Uchiyama et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Morphological and genetic analysis of three bacteriophages ofSerratia marcescensisolated from environmental water

(2008) Kenshi Matsushita et al.   FEMS MICROBIOLOGY LETTERS

Phages across the biosphere: contrasts of viruses in soil and aquatic environments

(2008) Sharath Srinivasiah et al.   RESEARCH IN MICROBIOLOGY

Isolation and characterisation of two novel coliphages with high potential to control antibiotic-resistant pathogenic Escherichia coli (EHEC and EPEC)

(2007) Maurizio Viscardi et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS