A Highly Active Chimeric Lysin with a Calcium-Enhanced Bactericidal Activity against Staphylococcus aureus In Vitro and In Vivo

Bacteriophages and Lysins in Biofilm Control

(2020) Marzanna Łusiak-Szelachowska et al.   VIROLOGICA SINICA

Advanced engineering of third-generation lysins and formulation strategies for clinical applications

(2020) Vincent De Maesschalck et al.   CRITICAL REVIEWS IN MICROBIOLOGY

ClyJ, a novel pneumococcal chimeric lysin with a CHAP catalytic domain

(2019) Hang Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Postantibiotic and Sub-MIC Effects of Exebacase (Lysin CF-301) Enhance Antimicrobial Activity Against Staphylococcus aureus

(2019) Jun Taek Oh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Antistaphylococcal Lysin, CF-301, Activates Key Host Factors in Human Blood To Potentiate Methicillin-Resistant Staphylococcus aureus Bacteriolysis

(2019) Chiara Indiani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emerging Strategies to Combat ESKAPE Pathogens in the Era of Antimicrobial Resistance: A Review

(2019) Mansura S. Mulani et al.   Frontiers in Microbiology

Kinetics of inactivation of staphylolytic enzymes: Qualitative and quantitative description

(2019) Lyubov Filatova et al.   BIOCHIMIE

Endolysins as emerging alternative therapeutic agent to counter drug resistant infections.

(2019) Vijay Singh Gondil et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Recombinant engineered phage-derived enzybiotic in Pichia pastoris X-33 as whole cell biocatalyst for effective biocontrol of Vibrio parahaemolyticus in aquaculture

(2019) Ramachandran Srinivasan et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Are Phage Lytic Proteins the Secret Weapon To Kill Staphylococcus aureus?

(2018) Diana Gutiérrez et al.   mBio

Staphylococcus aureus infection dynamics

(2018) Eric J. G. Pollitt et al.   PLoS Pathogens

A novel chimeric lysin with robust antibacterial activity against planktonic and biofilm methicillin-resistant Staphylococcus aureus

(2017) Hang Yang et al.   Scientific Reports

Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii

(2016) Mya Thandar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of a novel cell wall binding domain-containing Staphylococcus aureus endolysin LysSA97

(2016) Yoonjee Chang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Staphylococcus aureus: the current state of disease, pathophysiology and strategies for prevention

(2016) Gustavo H. Dayan et al.   Expert Review of Vaccines

A Thermophilic Phage Endolysin Fusion to a Clostridium perfringens-Specific Cell Wall Binding Domain Creates an Anti-Clostridium Antimicrobial with Improved Thermostability

(2015) Steven Swift et al.   Viruses-Basel

Isolation and Genome Characterization of the Virulent Staphylococcus aureus Bacteriophage SA97

(2015) Yoonjee Chang et al.   Viruses-Basel

A chimeolysin with extended-spectrum streptococcal host range found by an induced lysis-based rapid screening method

(2015) Hang Yang et al.   Scientific Reports

Intravitreal Injection of the Chimeric Phage Endolysin Ply187 Protects Mice from Staphylococcus aureus Endophthalmitis

(2014) Pawan Kumar Singh et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Engineered Endolysin-Based "Artilysins" To Combat Multidrug-Resistant Gram-Negative Pathogens

(2014) Y. Briers et al.   mBio

Structural and Biochemical Characterization Reveals LysGH15 as an Unprecedented “EF-Hand-Like” Calcium-Binding Phage Lysin

(2014) Jingmin Gu et al.   PLoS Pathogens

Construction of a chimeric lysin Ply187N-V12C with extended lytic activity against staphylococci and streptococci

(2014) Qiuhua Dong et al.   Microbial Biotechnology

Novel Chimeric Lysin with High-Level Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus In Vitro andIn Vivo

(2013) Hang Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel Bacteriophage Lysin with Broad Lytic Activity Protects against Mixed Infection by Streptococcus pyogenes and Methicillin-Resistant Staphylococcus aureus

(2013) Daniel B. Gilmer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Chimeric Ply187 endolysin killsStaphylococcus aureusmore effectively than the parental enzyme

(2013) Jinzhe Mao et al.   FEMS MICROBIOLOGY LETTERS

Peptidoglycan hydrolases-potential weapons against Staphylococcus aureus

(2012) Piotr Szweda et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Bacteriophage endolysins as novel antimicrobials

(2012) Mathias Schmelcher et al.   Future Microbiology

Staphylococcus aureusbiofilms

(2011) Nathan K. Archer et al.   Virulence

Domain shuffling and module engineering of Listeria phage endolysins for enhanced lytic activity and binding affinity

(2011) Mathias Schmelcher et al.   Microbial Biotechnology

Synergism between a Novel Chimeric Lysin and Oxacillin Protects against Infection by Methicillin-Resistant Staphylococcus aureus

(2010) A. Daniel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bacteriophage endolysins: A novel anti-infective to control Gram-positive pathogens

(2010) Vincent A. Fischetti   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Antimicrobial activity of a chimeric enzybiotic towards Staphylococcus aureus

(2008) Salim Manoharadas et al.   JOURNAL OF BIOTECHNOLOGY

The SWISS-MODEL Repository and associated resources

(2008) F. Kiefer et al.   NUCLEIC ACIDS RESEARCH

Characterization of a bacteriophage lysin (Ply700) from Streptococcus uberis

(2007) Laura K. Celia et al.   VETERINARY MICROBIOLOGY