In vitro and in vivo efficacy of combinations of colistin and different endolysins against clinical strains of multi-drug resistant pathogens

Molecular Mechanisms of Colistin-Induced Nephrotoxicity

(2019) Zhibo Gai et al.   MOLECULES

Isolation of phage lysins that effectively kill Pseudomonas aeruginosa in mouse models of lung and skin infection

(2019) Assaf Raz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro activity of methylene blue and eosin methylene blue agar on colistin-resistant A. baumannii: an experimental study

(2019) Deniz Gazel et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Combined Use of the Ab105-2φΔCI Lytic Mutant Phage and Different Antibiotics in Clinical Isolates of Multi-Resistant Acinetobacter baumannii

(2019) Lucia Blasco et al.   Microorganisms

Contribution of efflux to colistin heteroresistance in a multidrug resistant Acinetobacter baumannii clinical isolate

(2018) Diana Machado et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

In vitro characterization of PlyE146, a novel phage lysin that targets Gram-negative bacteria

(2018) Yu Larpin et al.   PLoS One

Evolution of the Quorum network and the mobilome (plasmids and bacteriophages) in clinical strains of Acinetobacter baumannii during a decade

(2018) M. López et al.   Scientific Reports

Effects of Phage Endolysin SAL200 Combined with Antibiotics on Staphylococcus aureus Infection

(2018) Nak-Hyun Kim et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bactericidal synergism between antibiotics and phage endolysin Cpl-711 to kill multidrug-resistant pneumococcus

(2018) Patricia Letrado et al.   Future Microbiology

In-silico interaction studies suggest RND efflux pump mediates polymyxin resistance in Acinetobacter baumannii

(2017) Privita Verma et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Contribution of EmrAB efflux pumps to colistin resistance in Acinetobacter baumannii

(2017) Ming-Feng Lin et al.   JOURNAL OF MICROBIOLOGY

Bacteriophage Transcytosis Provides a Mechanism To Cross Epithelial Cell Layers

(2017) Sophie Nguyen et al.   mBio

Evolution of the Pseudomonas aeruginosa mutational resistome in an international Cystic Fibrosis clone

(2017) Carla López-Causapé et al.   Scientific Reports

Effects of Efflux Pump Inhibitors on Colistin Resistance in Multidrug-Resistant Gram-Negative Bacteria

(2016) Wentao Ni et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antimicrobial peptides (AMPs) as drug candidates: a patent review (2003–2015)

(2016) Paulina Kosikowska et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Polymyxin Resistance in Acinetobacter baumannii: Genetic Mutations and Transcriptomic Changes in Response to Clinically Relevant Dosage Regimens

(2016) Soon-Ee Cheah et al.   Scientific Reports

Enhanced Antibacterial Activity of Acinetobacter baumannii Bacteriophage ØABP-01 Endolysin (LysABP-01) in Combination with Colistin

(2016) Rapee Thummeepak et al.   Frontiers in Microbiology

Structural and Enzymatic Characterization of ABgp46, a Novel Phage Endolysin with Broad Anti-Gram-Negative Bacterial Activity

(2016) Hugo Oliveira et al.   Frontiers in Microbiology

Novel Phage Lysin Capable of Killing the Multidrug-Resistant Gram-Negative Bacterium Acinetobacter baumannii in a Mouse Bacteremia Model

(2015) Rolf Lood et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A review on colistin nephrotoxicity

(2015) Atefeh Ordooei Javan et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

In vivo activity of daptomycin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection

(2015) Haifei Yang et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae

(2015) R. Diez-Martinez et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Art-175 Is a Highly Efficient Antibacterial against Multidrug-Resistant Strains and Persisters of Pseudomonas aeruginosa

(2014) Yves Briers et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Highly Active and Negatively Charged Streptococcus pyogenes Lysin with a Rare d-Alanyl-l-Alanine Endopeptidase Activity Protects Mice against Streptococcal Bacteremia

(2014) Rolf Lood et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Engineered Endolysin-Based "Artilysins" To Combat Multidrug-Resistant Gram-Negative Pathogens

(2014) Y. Briers et al.   mBio

Engineered bacteriophage lysins as novel anti-infectives

(2014) Hang Yang et al.   Frontiers in Microbiology

Novel Bacteriophage Lysin with Broad Lytic Activity Protects against Mixed Infection by Streptococcus pyogenes and Methicillin-Resistant Staphylococcus aureus

(2013) Daniel B. Gilmer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

phiBIOTICS: catalogue of therapeutic enzybiotics, relevant research studies and practical applications

(2013) Katarina Hojckova et al.   BMC MICROBIOLOGY

Chimeric Ply187 endolysin killsStaphylococcus aureusmore effectively than the parental enzyme

(2013) Jinzhe Mao et al.   FEMS MICROBIOLOGY LETTERS

A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity

(2013) Zakuan Z Deris et al.   JOURNAL OF ANTIBIOTICS

Molecular Aspects and Comparative Genomics of Bacteriophage Endolysins

(2013) H. Oliveira et al.   JOURNAL OF VIROLOGY

Chimeric Phage Lysins Act Synergistically with Lysostaphin To Kill Mastitis-Causing Staphylococcus aureus in Murine Mammary Glands

(2012) Mathias Schmelcher et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antibacterial activity of Acinetobacter baumannii phage ϕAB2 endolysin (LysAB2) against both Gram-positive and Gram-negative bacteria

(2011) Meng-Jiun Lai et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Use of bacteriophage endolysin EL188 and outer membrane permeabilizers against Pseudomonas aeruginosa

(2011) Y. Briers et al.   JOURNAL OF APPLIED MICROBIOLOGY

Structure-Based Modification of a Clostridium difficile-Targeting Endolysin Affects Activity and Host Range

(2011) M. J. Mayer et al.   JOURNAL OF BACTERIOLOGY

PHAST: A Fast Phage Search Tool

(2011) Y. Zhou et al.   NUCLEIC ACIDS RESEARCH

Synergy Testing by Etest, Microdilution Checkerboard, and Time-Kill Methods for Pan-Drug-Resistant Acinetobacter baumannii

(2010) M. M. Sopirala et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identifying Active Phage Lysins through Functional Viral Metagenomics

(2010) J. E. Schmitz et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Galleria mellonella as a Model System To Study Acinetobacter baumannii Pathogenesis and Therapeutics

(2009) A. Y. Peleg et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY