The relationship between CD4+ T cell glycolysis and their functions
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Title
The relationship between CD4+ T cell glycolysis and their functions
Authors
Keywords
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Journal
TRENDS IN ENDOCRINOLOGY AND METABOLISM
Volume 34, Issue 6, Pages 345-360
Publisher
Elsevier BV
Online
2023-04-14
DOI
10.1016/j.tem.2023.03.006
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Note: Only part of the references are listed.- Target c-Myc to treat pancreatic cancer
- (2022) Moein Ala CANCER BIOLOGY & THERAPY
- Targeting OXPHOS and the electronic transport chain in cancer; Molecular and therapeutic implications
- (2022) John Greene et al. SEMINARS IN CANCER BIOLOGY
- Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc
- (2022) Anna Krone et al. Scientific Reports
- The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming
- (2022) Sophia M. Hochrein et al. Cell Metabolism
- 1,25‐Dihydroxyvitamin D3 suppresses CD4 + T‐cell effector functionality by inhibition of glycolysis
- (2022) Emma L. Bishop et al. IMMUNOLOGY
- SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis
- (2022) Fei Sun et al. Cell Death & Disease
- T Cell Metabolism in Infection
- (2022) Jonas Aakre Wik et al. Frontiers in Immunology
- Alcohol Impairs Immunometabolism and Promotes Naïve T Cell Differentiation to Pro-Inflammatory Th1 CD4+ T Cells
- (2022) Patrick M. McTernan et al. Frontiers in Immunology
- Empagliflozin modulates CD4 + T‐cell differentiation via metabolic reprogramming in immune thrombocytopenia
- (2022) Jing Qin et al. BRITISH JOURNAL OF HAEMATOLOGY
- Sulfate oligosaccharide of Gracilaria lemaneiformis modulates type 1 immunity by restraining T cell activation
- (2022) Qingmei Liu et al. CARBOHYDRATE POLYMERS
- CaMK4 overexpression in polycystic kidney disease promotes mTOR-mediated cell proliferation
- (2022) Yan Zhang et al. Journal of Molecular Cell Biology
- The Effect of Lipid Metabolism on CD4+ T Cells
- (2021) Feiyang Cai et al. MEDIATORS OF INFLAMMATION
- The Role of mTOR Signaling as a Therapeutic Target in Cancer
- (2021) Nadezhda V. Popova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- HIF‑1α in myocardial ischemia‑reperfusion injury (Review)
- (2021) Jie Zheng et al. Molecular Medicine Reports
- CD4+ T-cell differentiation and function: Unifying glycolysis, fatty acid oxidation, polyamines NAD mitochondria
- (2021) Luís Almeida et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Cyclin-Dependent Kinase 7 Promotes Th17/Th1 Cell Differentiation in Psoriasis by Modulating Glycolytic Metabolism
- (2021) Yiting Lin et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- LKB1-PTEN axis controls Th1 and Th17 cell differentiation via regulating mTORC1
- (2021) Mahesh Pandit et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication
- (2021) Haitao Guo et al. NATURE IMMUNOLOGY
- The Acidic Brain—Glycolytic Switch in the Microenvironment of Malignant Glioma
- (2021) Anna Maria Reuss et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The MYC oncogene — the grand orchestrator of cancer growth and immune evasion
- (2021) Renumathy Dhanasekaran et al. Nature Reviews Clinical Oncology
- Targeting Mitochondrial-Derived Reactive Oxygen Species in T Cell-Mediated Autoimmune Diseases
- (2021) Miranda D. Chávez et al. Frontiers in Immunology
- Glycolysis Inhibition Induces Functional and Metabolic Exhaustion of CD4+ T Cells in Type 1 Diabetes
- (2021) Christina P. Martins et al. Frontiers in Immunology
- Reversal of Abnormal CD4+ T Cell Metabolism Alleviates Thyroiditis by Deactivating the mTOR/HIF1a/Glycolysis Pathway
- (2021) Lei Zhao et al. Frontiers in Endocrinology
- The mTOR–Autophagy Axis and the Control of Metabolism
- (2021) Nerea Deleyto-Seldas et al. Frontiers in Cell and Developmental Biology
- CD147 Is Essential for the Development of Psoriasis via the Induction of Th17 Cell Differentiation
- (2021) Aoi Okubo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
- (2021) Shanshan Duan et al. Cell Reports
- The Chemokine Receptor CCR5 Links Memory CD4+ T Cell Metabolism to T Cell Antigen Receptor Nanoclustering
- (2021) Raquel Blanco et al. Frontiers in Immunology
- Procyanidins: From Agro-Industrial Waste to Food as Bioactive Molecules
- (2021) Leidy Johana Valencia-Hernandez et al. Foods
- Monocarboxylate Transporters (SLC16): Function, Regulation, and Role in Health and Disease
- (2020) Melanie A. Felmlee et al. PHARMACOLOGICAL REVIEWS
- PVT1 Long Non-coding RNA in Gastrointestinal Cancer
- (2020) Águeda Martínez-Barriocanal et al. Frontiers in Oncology
- Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity
- (2020) Daniel DiToro et al. IMMUNITY
- mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges
- (2020) Zhilin Zou et al. Cell and Bioscience
- Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy
- (2020) Lin Wu et al. CELL
- Metformin and 2-Deoxyglucose Collaboratively Suppress Human CD4+ T Cell Effector Functions and Activation-Induced Metabolic Reprogramming
- (2020) Stefanie Y. Tan et al. JOURNAL OF IMMUNOLOGY
- Association of TIM-3 expression with glucose metabolism in Jurkat T cells
- (2020) Mi Jin Lee et al. BMC IMMUNOLOGY
- SerpinB1 expression in Th17 cells depends on hypoxia-inducible factor 1-alpha
- (2020) Lifei Hou et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Critical Role of AdipoR1 in Regulating Th17 Cell Differentiation Through Modulation of HIF-1α-Dependent Glycolysis
- (2020) Qian Zhang et al. Frontiers in Immunology
- mTOR Signaling in Metabolism and Cancer
- (2020) Shile Huang Cells
- The Many Faces of CD4+ T Cells: Immunological and Structural Characteristics
- (2020) Demetra S. M. Chatzileontiadou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- CD4+ T cell activation and concomitant mTOR metabolic inhibition can ablate microbiota-specific memory cells and prevent colitis
- (2020) Qing Zhao et al. Science Immunology
- Early life undernutrition reprograms CD4+ T-cell glycolysis and epigenetics to facilitate asthma
- (2019) Xi Chen et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Calcium Signaling Controls Pathogenic Th17 Cell-Mediated Inflammation by Regulating Mitochondrial Function
- (2019) Ulrike Kaufmann et al. Cell Metabolism
- Shikonin derivatives for cancer prevention and therapy
- (2019) Joelle C. Boulos et al. CANCER LETTERS
- CD28 Signaling Controls Metabolic Fitness of Pathogenic T Cells in Medium and Large Vessel Vasculitis
- (2019) Hui Zhang et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Metabolic reprogramming in memory CD4 T cell responses of old adults
- (2019) Rolando E. Yanes et al. CLINICAL IMMUNOLOGY
- Targeting T Cell Activation and Lupus Autoimmune Phenotypes by Inhibiting Glucose Transporters
- (2019) Wei Li et al. Frontiers in Immunology
- CD28 Autonomous Signaling Up-Regulates C-Myc Expression and Promotes Glycolysis Enabling Inflammatory T Cell Responses in Multiple Sclerosis
- (2019) Martina Kunkl et al. Cells
- The TCR is an allosterically regulated macromolecular machinery changing its conformation while working
- (2019) Wolfgang W. Schamel et al. IMMUNOLOGICAL REVIEWS
- Pharmacological properties and derivatives of shikonin—A review in recent years
- (2019) Chuanjie Guo et al. PHARMACOLOGICAL RESEARCH
- Shikonin attenuates hyperhomocysteinemia-induced CD4+ T cell inflammatory activation and atherosclerosis in ApoE−/− mice by metabolic suppression
- (2019) Si-lin Lü et al. ACTA PHARMACOLOGICA SINICA
- Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity
- (2019) Stefano Angiari et al. Cell Metabolism
- Particulate matter of 2.5 μm or less in diameter disturbs the balance of TH17/regulatory T cells by targeting glutamate oxaloacetate transaminase 1 and hypoxia-inducible factor 1α in an asthma model
- (2019) Licheng Sun et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- LncRNA PVT1 links Myc to glycolytic metabolism upon CD4+ T cell activation and Sjögren's syndrome-like autoimmune response
- (2019) Jiayao Fu et al. JOURNAL OF AUTOIMMUNITY
- Unraveling the Complex Interplay Between T Cell Metabolism and Function
- (2018) Ramon I. Klein Geltink et al. Annual Review of Immunology
- PKM2-dependent metabolic reprogramming in CD4+ T cells is crucial for hyperhomocysteinemia-accelerated atherosclerosis
- (2018) Silin Lü et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation
- (2018) Wei-Chan Hsu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Calcium/calmodulin-dependent protein kinase 4 promotes GLUT1-dependent glycolysis in systemic lupus erythematosus
- (2018) Tomohiro Koga et al. Arthritis & Rheumatology
- The Insulin Receptor Plays a Critical Role in T Cell Function and Adaptive Immunity
- (2017) Henrike J. Fischer et al. JOURNAL OF IMMUNOLOGY
- The role of CaMK4 in immune responses
- (2017) Tomohiro Koga et al. Modern Rheumatology
- THEMIS: Two Models, Different Thresholds
- (2017) Seeyoung Choi et al. TRENDS IN IMMUNOLOGY
- Reactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation
- (2017) Dana M. Previte et al. PLoS One
- Oxidative stress modulates the cytokine response of differentiated Th17 and Th1 cells
- (2016) Thiruvaimozhi Abimannan et al. FREE RADICAL BIOLOGY AND MEDICINE
- NADPH Oxidase–Derived Superoxide Provides a Third Signal for CD4 T Cell Effector Responses
- (2016) Lindsey E. Padgett et al. JOURNAL OF IMMUNOLOGY
- In human alloreactive CD4+ T-cells, dichloroacetate inhibits aerobic glycolysis, induces apoptosis and favors differentiation towards the regulatory T-cell subset instead of effector T-cell subsets
- (2016) THEODOROS ELEFTHERIADIS et al. Molecular Medicine Reports
- Bone Morphogenetic Proteins
- (2016) Takenobu Katagiri et al. Cold Spring Harbor Perspectives in Biology
- Glucose Metabolism in T Cells and Monocytes: New Perspectives in HIV Pathogenesis
- (2016) Clovis S. Palmer et al. EBioMedicine
- Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages
- (2015) Eva M. Palsson-McDermott et al. Cell Metabolism
- THEMIS: a critical TCR signal regulator for ligand discrimination
- (2015) Nicholas RJ Gascoigne et al. CURRENT OPINION IN IMMUNOLOGY
- Glucose, glycolysis and lymphocyte responses
- (2015) Raymond P. Donnelly et al. MOLECULAR IMMUNOLOGY
- Oligomeric Procyanidins Interfere with Glycolysis of Activated T Cells. A Novel Mechanism for Inhibition of T Cell Function
- (2015) Masao Goto et al. MOLECULES
- Normalization of CD4 + T cell metabolism reverses lupus
- (2015) Yiming Yin et al. Science Translational Medicine
- Targeting T cell metabolism for therapy
- (2015) David O'Sullivan et al. TRENDS IN IMMUNOLOGY
- Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions
- (2015) Clovis S. Palmer et al. Frontiers in Immunology
- An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins – From superoxide dismutation to H 2 O 2 -driven pathways
- (2015) Ines Batinic-Haberle et al. Redox Biology
- The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function
- (2014) Andrew N. Macintyre et al. Cell Metabolism
- SUMO Ubc9 enzyme as a viral target
- (2014) Archana Varadaraj et al. IUBMB LIFE
- PVT1 dependence in cancer with MYC copy-number increase
- (2014) Yuen-Yi Tseng et al. NATURE
- Metabolic Regulation of T Lymphocytes
- (2013) Nancie J. MacIver et al. Annual Review of Immunology
- Tumor glycolysis as a target for cancer therapy: progress and prospects
- (2013) Shanmugasundaram Ganapathy-Kanniappan et al. Molecular Cancer
- Advances in understanding the pathogenesis of primary Sjögren's syndrome
- (2013) Gaëtane Nocturne et al. Nature Reviews Rheumatology
- Fueling Immunity: Insights into Metabolism and Lymphocyte Function
- (2013) E. L. Pearce et al. SCIENCE
- The T cell in Sjogren's syndrome: Force majeure, not spectateur
- (2012) Namrata Singh et al. JOURNAL OF AUTOIMMUNITY
- The origins, function, and regulation of T follicular helper cells
- (2012) Cindy S. Ma et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The role of low-level lactate production in airway inflammation in asthma
- (2011) Marina Ostroukhova et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
- (2011) Greg M Delgoffe et al. NATURE IMMUNOLOGY
- Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities
- (2010) Ines Batinic-Haberle et al. AMINO ACIDS
- Differentiation of Effector CD4 T Cell Populations
- (2010) Jinfang Zhu et al. Annual Review of Immunology
- The metabolic life and times of a T-cell
- (2010) Ryan D. Michalek et al. IMMUNOLOGICAL REVIEWS
- SGLT2 inhibition — a novel strategy for diabetes treatment
- (2010) Edward C. Chao et al. NATURE REVIEWS DRUG DISCOVERY
- mTOR: from growth signal integration to cancer, diabetes and ageing
- (2010) Roberto Zoncu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation
- (2009) Björn F Lillemeier et al. NATURE IMMUNOLOGY
- CD4 T cells: fates, functions, and faults
- (2008) J. Zhu et al. BLOOD
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