DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
DUSP6 mediates T cell receptor-engaged glycolysis and restrains TFH cell differentiation
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 115, Issue 34, Pages E8027-E8036
Publisher
Proceedings of the National Academy of Sciences
Online
2018-08-08
DOI
10.1073/pnas.1800076115
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The IRF4 Gene Regulatory Module Functions as a Read-Write Integrator to Dynamically Coordinate T Helper Cell Fate
- (2017) Veena Krishnamoorthy et al. IMMUNITY
- AMP kinase promotes Bcl6 expression in both mouse and human T cells
- (2017) Markus M. Xie et al. MOLECULAR IMMUNOLOGY
- Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming
- (2016) Michael D. Buck et al. CELL
- The PI3K pathway in B cell metabolism
- (2016) Julia Jellusova et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation
- (2016) Hu Zeng et al. IMMUNITY
- Peyer's patches: organizing B-cell responses at the intestinal frontier
- (2016) Andrea Reboldi et al. IMMUNOLOGICAL REVIEWS
- Cutting Edge: NFAT Transcription Factors Promote the Generation of Follicular Helper T Cells in Response to Acute Viral Infection
- (2016) Gustavo J. Martinez et al. JOURNAL OF IMMUNOLOGY
- Metabolic pathways in T cell activation and lineage differentiation
- (2016) Luís Almeida et al. SEMINARS IN IMMUNOLOGY
- Genome-wide Analysis Identifies Bcl6-Controlled Regulatory Networks during T Follicular Helper Cell Differentiation
- (2016) Xindong Liu et al. Cell Reports
- Dual-specificity phosphatase 6 deficiency regulates gut microbiome and transcriptome response against diet-induced obesity in mice
- (2016) Jhen-Wei Ruan et al. Nature Microbiology
- Hepatitis C virus-induced reduction in miR-181a impairs CD4+T-cell responses through overexpression of DUSP6
- (2015) Guang Y. Li et al. HEPATOLOGY
- The Immune-Metabolic Basis of Effector Memory CD4+T Cell Function under Hypoxic Conditions
- (2015) Sarah Dimeloe et al. JOURNAL OF IMMUNOLOGY
- Nck adaptor proteins modulate differentiation and effector function of T cells
- (2015) Kun-Hui Lu et al. JOURNAL OF LEUKOCYTE BIOLOGY
- TCR ITAM multiplicity is required for the generation of follicular helper T-cells
- (2015) SuJin Hwang et al. Nature Communications
- Phosphofructokinase: A mediator of glycolytic flux in cancer progression
- (2014) Nada Al Hasawi et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Mitogen-Activated Protein Kinase Phosphatase 3 (MKP-3)-Deficient Mice Are Resistant to Diet-Induced Obesity
- (2014) B. Feng et al. DIABETES
- CD4 T cell defects in the aged: Causes, consequences and strategies to circumvent
- (2014) Wenliang Zhang et al. EXPERIMENTAL GERONTOLOGY
- Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways
- (2014) S. R. Jacobs et al. JOURNAL OF IMMUNOLOGY
- Metabolic Reprogramming Is Required for Antibody Production That Is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B Cells
- (2014) A. Caro-Maldonado et al. JOURNAL OF IMMUNOLOGY
- Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice
- (2014) S Bertin et al. Mucosal Immunology
- Bcl-6 directly represses the gene program of the glycolysis pathway
- (2014) Kenneth J Oestreich et al. NATURE IMMUNOLOGY
- Mitogen-activated protein kinase (MAPK) phosphatase-3 (MKP-3) displays a p-JNK-MAPK substrate preference in astrocytes in vitro
- (2014) Christian Ndong et al. NEUROSCIENCE LETTERS
- Follicular helper T-cell memory: establishing new frontiers during antibody response
- (2013) Louis M Tsai et al. IMMUNOLOGY AND CELL BIOLOGY
- Functional STAT3 deficiency compromises the generation of human T follicular helper cells
- (2012) C. S. Ma et al. BLOOD
- Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation
- (2012) André Ballesteros-Tato et al. IMMUNITY
- Metabolic switching and fuel choice during T-cell differentiation and memory development
- (2012) Gerritje J. W. Windt et al. IMMUNOLOGICAL REVIEWS
- STAT5 Protein Negatively Regulates T Follicular Helper (Tfh) Cell Generation and Function
- (2012) Roza I. Nurieva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STAT5 is a potent negative regulator of TFHcell differentiation
- (2012) Robert J. Johnston et al. JOURNAL OF EXPERIMENTAL MEDICINE
- MEK/ERK pathway mediates insulin-promoted degradation of MKP-3 protein in liver cells
- (2012) Bin Feng et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Metabolic checkpoints in activated T cells
- (2012) Ruoning Wang et al. NATURE IMMUNOLOGY
- Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile
- (2012) Kenneth J Oestreich et al. NATURE IMMUNOLOGY
- Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity
- (2012) Guangjin Li et al. NATURE MEDICINE
- Follicular Helper CD4 T Cells (TFH)
- (2011) Shane Crotty Annual Review of Immunology
- Mitogen-activated Protein Kinase (MAPK) Phosphatase 3-mediated Cross-talk between MAPKs ERK2 and p38α
- (2011) Yuan-Yuan Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1
- (2010) M. J. Seltzer et al. CANCER RESEARCH
- Mammalian Target of Rapamycin Protein Complex 2 Regulates Differentiation of Th1 and Th2 Cell Subsets via Distinct Signaling Pathways
- (2010) Keunwook Lee et al. IMMUNITY
- Regulation of mammalian muscle type 6-phosphofructo-1-kinase and its implication for the control of the metabolism
- (2010) Mauro Sola-Penna et al. IUBMB LIFE
- MAPK phosphatase–3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box O1 in mice
- (2010) Zhidan Wu et al. JOURNAL OF CLINICAL INVESTIGATION
- Induction of Glucose Metabolism in Stimulated T Lymphocytes Is Regulated by Mitogen-Activated Protein Kinase Signaling
- (2010) Aimee J. Marko et al. PLoS One
- mTOR phosphorylated at S2448 binds to raptor and rictor
- (2009) M. Rosner et al. AMINO ACIDS
- The Transcriptional Repressor Bcl-6 Directs T Follicular Helper Cell Lineage Commitment
- (2009) Di Yu et al. IMMUNITY
- Early commitment of naïve human CD4+ T cells to the T follicular helper (TFH ) cell lineage is induced by IL-12
- (2009) Cindy S Ma et al. IMMUNOLOGY AND CELL BIOLOGY
- Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages
- (2009) Gabriela Molina et al. Nature Chemical Biology
- The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding
- (2009) Nicolas Fazilleau et al. NATURE IMMUNOLOGY
- Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation
- (2009) R. J. Johnston et al. SCIENCE
- Bcl6 Mediates the Development of T Follicular Helper Cells
- (2009) R. I. Nurieva et al. SCIENCE
- Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
- (2008) Candace M. Cham et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Generation of T Follicular Helper Cells Is Mediated by Interleukin-21 but Independent of T Helper 1, 2, or 17 Cell Lineages
- (2008) Roza I. Nurieva et al. IMMUNITY
- DUSP6 (MKP3) Null Mice Show Enhanced ERK1/2 Phosphorylation at Baseline and Increased Myocyte Proliferation in the Heart Affecting Disease Susceptibility
- (2008) Marjorie Maillet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search