A Strategy for Accessing Trifluoromethyl Carbinol-Containing Chromones from o-Hydroxyaryl Enaminones and Trifluoroacetaldehyde/Ketone Derivatives

A Traceless Heterocyclic Amine Mediator in Regioselectivity−Switchable Formal [1 + 2 + 2] Cycloaddition Reaction to 1,3,4- and 1,4,5-Trisubstituted Pyrazoles

(2023) Jie Huo et al.   Organic Letters

Photoredox-Catalyzed Cascade of o-Hydroxyarylenaminones to Access 3-Aminated Chromones

(2022) Zhi-Wei Wang et al.   JOURNAL OF ORGANIC CHEMISTRY

A Straightforward Approach to Fluorinated Pyrimido[1,2-b]indazole Derivatives via Metal/Additive-Free Annulation with Enaminones, 3-Aminoindazoles, and Selectfluor

(2022) Zhaoliang Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Copper-Mediated Cyclization of o-Hydroxyaryl Enaminones with 3-Indoleacetic Acids toward the Synthesis of 3-Indolmethyl-Chromones

(2022) Kangmei Wen et al.   JOURNAL OF ORGANIC CHEMISTRY

Electrochemical C-H Halogenations of Enaminones and Electron-Rich Arenes with Sodium Halide (NaX) as Halogen Source for the Synthesis of 3-Halochromones and Haloarenes

(2021) Yan Lin et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 3,3-Dihalogenated 2-Aminochromanones via Tandem Dihalogenation and Cyclization of o-Hydroxyarylenaminones with NXS (X = Cl or Br)

(2021) Tian Luo et al.   JOURNAL OF ORGANIC CHEMISTRY

Visible-Light-Driven Multicomponent Cyclization by Trapping a 1,3-Vinylimine Ion Intermediate: A Direct Approach to Pyrimido[1,2-b]indazole Derivatives

(2021) Xiao Geng et al.   ORGANIC LETTERS

A practical synthesis of α-bromo/iodo/chloroketones from olefins under visible-light irradiation conditions

(2020) Zhihui Wang et al.   CHINESE CHEMICAL LETTERS

Free-Radical-Promoted Dehydrogenative Coupling of Polyfluorinated Alcohol with Quinone, Chromone, and Coumarin

(2020) Jingping Liu et al.   ORGANIC LETTERS

The Domino Chromone Annulation and a Transient Halogenation-Mediated C–H Alkenylation toward 3-Vinyl Chromones

(2020) Leiqing Fu et al.   ORGANIC LETTERS

Visible Light-Induced Thiocyanation of Enaminone C-H Bond to Access Polyfunctionalized Alkenes and Thiocyano Chromones

(2019) Yong Gao et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 3-HCF2S-Chromones through Tandem Oxa-Michael Addition and Oxidative Difluoromethylthiolation

(2019) Pingshun Zhang et al.   ORGANIC LETTERS

Chromone as a Privileged Scaffold in Drug Discovery: Recent Advances

(2017) Joana Reis et al.   JOURNAL OF MEDICINAL CHEMISTRY

C2-Symmetric Chiral Bisoxazolines as Hydrogen-Bond-Acceptor Catalysts in Enantioselective Aldol Reaction of β-Carbonyl Acids with Trifluoroacetaldehyde Hemiacetals

(2016) Zhen-Yan Yang et al.   ORGANIC LETTERS

A Free-Radical-Promoted Site-Specific Cross-Dehydrogenative-Coupling of N-Heterocycles with Fluorinated Alcohols

(2016) Zhengbao Xu et al.   ORGANIC LETTERS

Free-Radical Triggered Ordered Domino Reaction: An Approach to C–C Bond Formation via Selective Functionalization of α-Hydroxyl-(sp3)C–H in Fluorinated Alcohols

(2016) Zhengbao Xu et al.   ORGANIC LETTERS

Visible-Light-Driven, Radical-Triggered Tandem Cyclization of o-Hydroxyaryl Enaminones: Facile Access to 3-CF2 /CF3-Containing Chromones

(2016) Haoyue Xiang et al.   ORGANIC LETTERS

Applications of Fluorine in Medicinal Chemistry

(2015) Eric P. Gillis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chromone: A Valid Scaffold in Medicinal Chemistry

(2014) Alexandra Gaspar et al.   CHEMICAL REVIEWS

A Facile and General Approach to 3-((Trifluoromethyl)thio)-4H-chromen-4-one

(2014) Haoyue Xiang et al.   ORGANIC LETTERS

Nonsteroidal Dissociated Glucocorticoid Agonists Containing Azaindoles as Steroid A-Ring Mimetics

(2010) Doris Riether et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS