Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 86, Issue 17, Pages 12378-12385Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.1c01347
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Funding
- National Natural Science Foundation of China [21562024]
- Natural Science Foundation of Jiangxi Province [20202BABL203008]
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This electrochemical method allows for the simple synthesis of 3-halochromones and various halogenated electron-rich arenes without the need for an external oxidant. It is advantageous for its simple and mild room temperature operation, environmental friendliness, and broad substrate scope.
Without employing an external oxidant, the simple synthesis of 3-halochromones and various halogenated electron-rich arenes has been realized with electrode oxidation by employing the simplest sodium halide (NaX, X = Cl, Br, I) as halogen source. This electrochemical method is advantageous for the simple and mild room temperature operation, environmental friendliness as well as broad substrate scope in both C-H bond donor and halogen source components.
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