Journal
ORGANIC LETTERS
Volume 22, Issue 24, Pages 9518-9523Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c03548
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Funding
- National Natural Science Foundation of China [21861019]
- Natural Science Foundation of Jiangxi Province [20202ACBL203006]
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Reported in this paper is a step economical method toward the general synthesis of 3-vinyl chromones via the reactions between readily available o-hydroxyphenyl enaminones and various alkenes. The domino C-H alkenylation and chromone annulation of the enaminones are involved, which enables the synthesis of 3-vinyl chromone products using both terminal and internal alkenes via a key process of transient C-H halogenation.
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