- Home
- Publications
- Publication Search
- Publication Details
Title
Label-Free Optical Metabolic Imaging in Cells and Tissues
Authors
Keywords
-
Journal
Annual Review of Biomedical Engineering
Volume 25, Issue 1, Pages 413-443
Publisher
Annual Reviews
Online
2023-04-28
DOI
10.1146/annurev-bioeng-071516-044730
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Multispectral autofluorescence characteristics of reproductive aging in old and young mouse oocytes
- (2022) Jared M. Campbell et al. BIOGERONTOLOGY
- Deep learning autofluorescence-harmonic microscopy
- (2022) Binglin Shen et al. Light-Science & Applications
- Multimodal analyses of vitiligo skin identifies tissue characteristics of stable disease
- (2022) Jessica Shiu et al. JCI Insight
- Riboflavin depletion promotes longevity and metabolic hormesis in Caenorhabditis elegans
- (2022) Armen Yerevanian et al. AGING CELL
- Automated Extraction of Skin Wound Healing Biomarkers From In Vivo Label‐Free Multiphoton Microscopy Using Convolutional Neural Networks
- (2021) Jake D. Jones et al. LASERS IN SURGERY AND MEDICINE
- Optoacoustic imaging in endocrinology and metabolism
- (2021) Angelos Karlas et al. Nature Reviews Endocrinology
- Multimodal, label-free fluorescence and Raman imaging of amyloid deposits in snap-frozen Alzheimer’s disease human brain tissue
- (2021) Benjamin Lochocki et al. Communications Biology
- Visualization of intracellular lipid metabolism in brown adipocytes by time-lapse ultra-multiplex CARS microspectroscopy with an onstage incubator
- (2021) Yuki Takei et al. JOURNAL OF CHEMICAL PHYSICS
- Deep Learning in Biomedical Optics
- (2021) Lei Tian et al. LASERS IN SURGERY AND MEDICINE
- Method of transmission filters to measure emission spectra in strongly scattering media
- (2021) Belén Torrado et al. Biomedical Optics Express
- Phasor-based hyperspectral snapshot microscopy allows fast imaging of live, three-dimensional tissues for biomedical applications
- (2021) Per Niklas Hedde et al. Communications Biology
- Phototoxicity induced in living HeLa cells by focused femtosecond laser pulses: a data-driven approach
- (2021) B. Talone et al. Biomedical Optics Express
- Carotenoids and carotenoid conversion products in adipose tissue biology and obesity: Pre-clinical and human studies
- (2020) M. Luisa Bonet et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Fluorescence lifetime imaging microscopy: fundamentals and advances in instrumentation, analysis, and applications
- (2020) Rupsa Datta et al. JOURNAL OF BIOMEDICAL OPTICS
- Dehydrogenase Binding Sites Abolish the “Dark” Fraction of NADH: Implication for Metabolic Sensing via FLIM
- (2020) Simin Cao et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Label-free metabolic biomarkers for assessing valve interstitial cell calcific progression
- (2020) Ishita Tandon et al. Scientific Reports
- Noninvasive two-photon optical biopsy of retinal fluorophores
- (2020) Grazyna Palczewska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Considerations for using isolated cell systems to understand cardiac metabolism and biology
- (2020) Lindsey A. McNally et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Quantifying Age-Related Changes in Skin Wound Metabolism Using In Vivo Multiphoton Microscopy
- (2019) Jake D. Jones et al. Advances in Wound Care
- Fast fit-free analysis of fluorescence lifetime imaging via deep learning
- (2019) Jason T. Smith et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evaluating Cell Metabolism Through Autofluorescence Imaging of NAD(P)H and FAD
- (2018) Olivia I. Kolenc et al. ANTIOXIDANTS & REDOX SIGNALING
- NAD(H) and NADP(H) Redox Couples and Cellular Energy Metabolism
- (2018) Wusheng Xiao et al. ANTIOXIDANTS & REDOX SIGNALING
- Visualization of Breast Cancer Metabolism Using Multimodal Nonlinear Optical Microscopy of Cellular Lipids and Redox State
- (2018) Jue Hou et al. CANCER RESEARCH
- Mitochondrial dynamics: overview of molecular mechanisms
- (2018) Lisa Tilokani et al. Essays in Biochemistry
- Hyperspectral imaging in highly scattering media by the spectral phasor approach using two filters
- (2018) Alexander Dvornikov et al. Biomedical Optics Express
- Mapping metabolic changes by noninvasive, multiparametric, high-resolution imaging using endogenous contrast
- (2018) Zhiyi Liu et al. Science Advances
- NADH Autofluorescence-A Marker on its Way to Boost Bioenergetic Research
- (2018) Patrick M. Schaefer et al. CYTOMETRY PART A
- Fit-free analysis of fluorescence lifetime imaging data using the phasor approach
- (2018) Suman Ranjit et al. Nature Protocols
- Imaging tumour hypoxia with oxygen-enhanced MRI and BOLD MRI
- (2018) James O'Connor et al. BRITISH JOURNAL OF RADIOLOGY
- Scattering reduction by structured light illumination in line-scanning temporal focusing microscopy
- (2018) Yi Xue et al. Biomedical Optics Express
- Rapid quantification of mitochondrial fractal dimension in individual cells
- (2018) Isaac Vargas et al. Biomedical Optics Express
- Investigating the healing mechanisms of an angiogenesis-promoting topical treatment for diabetic wounds using multimodal microscopy
- (2017) Joanne Li et al. Journal of Biophotonics
- Fluorescence lifetime imaging ophthalmoscopy
- (2017) Chantal Dysli et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity
- (2017) Emily Stuntz et al. Scientific Reports
- Mitochondrial matrix pH as a decisive factor in neurometabolic imaging
- (2017) Patrick M. Schaefer et al. Neurophotonics
- Concurrence of extracellular vesicle enrichment and metabolic switch visualized label-free in the tumor microenvironment
- (2017) Haohua Tu et al. Science Advances
- Investigating mitochondrial redox state using NADH and NADPH autofluorescence
- (2016) Thomas S. Blacker et al. FREE RADICAL BIOLOGY AND MEDICINE
- Apollo-NADP+: a spectrally tunable family of genetically encoded sensors for NADP+
- (2016) William D Cameron et al. NATURE METHODS
- Stain-free histopathology by programmable supercontinuum pulses
- (2016) Haohua Tu et al. Nature Photonics
- Imaging mitochondrial dynamics in human skin reveals depth-dependent hypoxia and malignant potential for diagnosis
- (2016) D. Pouli et al. Science Translational Medicine
- Temporal binning of time-correlated single photon counting data improves exponential decay fits and imaging speed
- (2016) Alex J. Walsh et al. Biomedical Optics Express
- Measurements of absolute concentrations of NADH in cells using the phasor FLIM method
- (2016) Ning Ma et al. Biomedical Optics Express
- Automated analysis of multimodal fluorescence lifetime imaging and optical coherence tomography data for the diagnosis of oral cancer in the hamster cheek pouch model
- (2016) Paritosh Pande et al. Biomedical Optics Express
- Optical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism
- (2016) Kinan Alhallak et al. Biomedical Optics Express
- Two-photon excited fluorescence of intrinsic fluorophores enables label-free assessment of adipose tissue function
- (2016) Carlo Amadeo Alonzo et al. Scientific Reports
- Reversible Fluorescent Probes for Biological Redox States
- (2015) Amandeep Kaur et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight
- (2015) Aashiq Hussain Bhat et al. BIOMEDICINE & PHARMACOTHERAPY
- Intravital autofluorescence 2-photon microscopy of murine intestinal mucosa with ultra-broadband femtosecond laser pulse excitation: image quality, photodamage, and inflammation
- (2015) Antje Klinger et al. JOURNAL OF BIOMEDICAL OPTICS
- High-throughput measurements of the optical redox ratio using a commercial microplate reader
- (2015) Taylor M. Cannon et al. JOURNAL OF BIOMEDICAL OPTICS
- Review of short-wave infrared spectroscopy and imaging methods for biological tissue characterization
- (2015) Robert H. Wilson et al. JOURNAL OF BIOMEDICAL OPTICS
- Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine
- (2015) J.-X. Cheng et al. SCIENCE
- Quantitative Optical Imaging of Primary Tumor Organoid Metabolism Predicts Drug Response in Breast Cancer
- (2014) A. J. Walsh et al. CANCER RESEARCH
- Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
- (2014) A. Varone et al. CANCER RESEARCH
- Noninvasive assessment of mitochondrial organization in three-dimensional tissues reveals changes associated with cancer development
- (2014) Joanna Xylas et al. INTERNATIONAL JOURNAL OF CANCER
- Intrinsic Indicator of Photodamage during Label-Free Multiphoton Microscopy of Cells and Tissues
- (2014) Roberta Galli et al. PLoS One
- Separating NADH and NADPH fluorescence in live cells and tissues using FLIM
- (2014) Thomas S. Blacker et al. Nature Communications
- Non-invasive monitoring of cell metabolism and lipid production in 3D engineered human adipose tissues using label-free multiphoton microscopy
- (2013) Tyler Chang et al. BIOMATERIALS
- Use of multiphoton tomography and fluorescence lifetime imaging to investigate skin pigmentationin vivo
- (2013) Yuri Dancik et al. JOURNAL OF BIOMEDICAL OPTICS
- Advances in multiphoton microscopy technology
- (2013) Erich E. Hoover et al. Nature Photonics
- Quantitative metabolic imaging using endogenous fluorescence to detect stem cell differentiation
- (2013) Kyle P. Quinn et al. Scientific Reports
- Quantitative redox imaging biomarkers for studying tissue metabolic state and its heterogeneity
- (2013) He N. Xu et al. Journal of Innovative Optical Health Sciences
- Optical Imaging Using Endogenous Contrast to Assess Metabolic State
- (2012) Irene Georgakoudi et al. Annual Review of Biomedical Engineering
- Characterization of metabolic changes associated with the functional development of 3D engineered tissues by non-invasive, dynamic measurement of individual cell redox ratios
- (2012) Kyle P. Quinn et al. BIOMATERIALS
- Label-free separation of human embryonic stem cells and their differentiating progenies by phasor fluorescence lifetime microscopy
- (2012) Chiara Stringari JOURNAL OF BIOMEDICAL OPTICS
- Two-photon excited fluorescence lifetime imaging and spectroscopy of melaninsin vitroandin vivo
- (2012) Tatiana B. Krasieva et al. JOURNAL OF BIOMEDICAL OPTICS
- Carcinogenic damage to deoxyribonucleic acid is induced by near-infrared laser pulses in multiphoton microscopy via combination of two- and three-photon absorption
- (2012) Oleg Nadiarnykh et al. JOURNAL OF BIOMEDICAL OPTICS
- Improved Fourier-based characterization of intracellular fractal features
- (2012) Joanna Xylas et al. OPTICS EXPRESS
- Spatiotemporal focusing-based widefield multiphoton microscopy for fast optical sectioning
- (2012) Li-Chung Cheng et al. OPTICS EXPRESS
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Imaging Cytosolic NADH-NAD+ Redox State with a Genetically Encoded Fluorescent Biosensor
- (2011) Yin Pun Hung et al. Cell Metabolism
- Label-free imaging of lipid dynamics using Coherent Anti-stokes Raman Scattering (CARS) and Stimulated Raman Scattering (SRS) microscopy
- (2011) Andrew Folick et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Automated Biochemical, Morphological, and Organizational Assessment of Precancerous Changes from Endogenous Two-Photon Fluorescence Images
- (2011) Jonathan M. Levitt et al. PLoS One
- Phasor approach to fluorescence lifetime microscopy distinguishes different metabolic states of germ cells in a live tissue
- (2011) C. Stringari et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies
- (2010) Ahmed A Heikal Biomarkers in Medicine
- Simultaneous optical coherence tomography and laser induced fluorescence imaging in rat model of ovarian carcinogenesis
- (2010) Lida P. Hariri et al. CANCER BIOLOGY & THERAPY
- Optical Redox Ratio Differentiates Breast Cancer Cell Lines Based on Estrogen Receptor Status
- (2010) Julie Hanson Ostrander et al. CANCER RESEARCH
- A review on the clinical uses of SPECT/CT
- (2010) Giuliano Mariani et al. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
- Quantitative mitochondrial redox imaging of breast cancer metastatic potential
- (2010) He N. Xu et al. JOURNAL OF BIOMEDICAL OPTICS
- Two-Photon NADH Imaging Exposes Boundaries of Oxygen Diffusion in Cortical Vascular Supply Regions
- (2010) Karl A Kasischke et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Assessment of in vivo 1H magnetic resonance spectroscopy in the liver: a review
- (2010) Frank Fischbach et al. LIVER INTERNATIONAL
- Multiphoton excitation characteristics of cellular fluorophores of human skin in vivo
- (2010) Hans Georg Breunig et al. OPTICS EXPRESS
- Two-Photon Microscopy for Non-Invasive, Quantitative Monitoring of Stem Cell Differentiation
- (2010) William L. Rice et al. PLoS One
- Assessing hemoglobin concentration using spectroscopic optical coherence tomography for feasibility of tissue diagnostics
- (2010) Francisco E. Robles et al. Biomedical Optics Express
- A dual-modality optical coherence tomography and fluorescence lifetime imaging microscopy system for simultaneous morphological and biochemical tissue characterization
- (2010) Jesung Park et al. Biomedical Optics Express
- Spectral fluorescence lifetime detection and selective melanin imaging by multiphoton laser tomography for melanoma diagnosis
- (2009) Enrico Dimitrow et al. EXPERIMENTAL DERMATOLOGY
- PET versus SPECT: strengths, limitations and challenges
- (2009) Arman Rahmim et al. NUCLEAR MEDICINE COMMUNICATIONS
- A hyperfused mitochondrial state achieved at G1-S regulates cyclin E buildup and entry into S phase
- (2009) K. Mitra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondrial NADH Fluorescence Is Enhanced by Complex I Binding
- (2008) Ksenia Blinova et al. BIOCHEMISTRY
- Magnetic resonance spectroscopy of the brain: review of metabolites and clinical applications
- (2008) D.P. Soares et al. CLINICAL RADIOLOGY
- Two-photon autofluorescence dynamics imaging reveals sensitivity of intracellular NADH concentration and conformation to cell physiology at the single-cell level
- (2008) Qianru Yu et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- Retinal Pigment Epithelium Lipofuscin Proteomics
- (2008) Kwok-Peng Ng et al. MOLECULAR & CELLULAR PROTEOMICS
- NAD+/NADH and NADP+/NADPH in Cellular Functions and Cell Death: Regulation and Biological Consequences
- (2007) Weihai Ying ANTIOXIDANTS & REDOX SIGNALING
- The Phasor Approach to Fluorescence Lifetime Imaging Analysis
- (2007) Michelle A. Digman et al. BIOPHYSICAL JOURNAL
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started