The structure of DarB in complex with Rel NTD reveals nonribosomal activation of Rel stringent factors
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The structure of DarB in complex with Rel
NTD
reveals nonribosomal activation of Rel stringent factors
Authors
Keywords
-
Journal
Science Advances
Volume 9, Issue 3, Pages -
Publisher
American Association for the Advancement of Science (AAAS)
Online
2023-01-19
DOI
10.1126/sciadv.ade4077
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Direct activation of a bacterial innate immune system by a viral capsid protein
- (2022) Tong Zhang et al. NATURE
- Structure of SpoT reveals evolutionary tuning of catalysis via conformational constraint
- (2022) Hedvig Tamman et al. Nature Chemical Biology
- A meet-up of two second messengers: the c-di-AMP receptor DarB controls (p)ppGpp synthesis in Bacillus subtilis
- (2021) Larissa Krüger et al. Nature Communications
- Nonhydrolysable Analogues of (p)ppGpp and (p)ppApp Alarmone Nucleotides as Novel Molecular Tools
- (2021) Viktor Mojr et al. ACS Chemical Biology
- Regulatory Themes and Variations by the Stress-Signaling Nucleotide Alarmones (p)ppGpp in Bacteria
- (2021) Brent W. Anderson et al. Annual Review of Genetics
- Two P or Not Two P: Understanding Regulation by the Bacterial Second Messengers (p)ppGpp
- (2021) Gert Bange et al. Annual Review of Microbiology
- (p)ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains
- (2021) Mohammad Roghanian et al. MOLECULAR CELL
- NirD curtails the stringent response by inhibiting RelA activity in Escherichia coli
- (2021) Loïc Léger et al. eLife
- The current state of SubtiWiki, the database for the model organism Bacillus subtilis
- (2021) Tiago Pedreira et al. NUCLEIC ACIDS RESEARCH
- Cyclic di-AMP, a second messenger of primary importance: tertiary structures and binding mechanisms
- (2020) Jin He et al. NUCLEIC ACIDS RESEARCH
- The C-Terminal RRM/ACT Domain Is Crucial for Fine-Tuning the Activation of ‘Long’ RelA-SpoT Homolog Enzymes by Ribosomal Complexes
- (2020) Hiraku Takada et al. Frontiers in Microbiology
- A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes
- (2020) Hedvig Tamman et al. Nature Chemical Biology
- A widespread toxin−antitoxin system exploiting growth control via alarmone signaling
- (2020) Steffi Jimmy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclic di-AMP Signaling in Bacteria
- (2020) Jörg Stülke et al. Annual Review of Microbiology
- (p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes
- (2020) Bret N. Peterson et al. mBio
- The protein translation machinery is expressed for maximal efficiency in Escherichia coli
- (2020) Xiao-Pan Hu et al. Nature Communications
- Structural Basis for Regulation of the Opposing (p)ppGpp Synthetase and Hydrolase within the Stringent Response Orchestrator Rel
- (2020) Patrick Pausch et al. Cell Reports
- Ribosome association primes the stringent factor Rel for tRNA-dependent locking in the A-site and activation of (p)ppGpp synthesis
- (2020) Hiraku Takada et al. NUCLEIC ACIDS RESEARCH
- The Rel stringent factor from Thermus thermophilus: crystallization and X-ray analysis
- (2019) Katleen Van Nerom et al. Acta Crystallographica Section F-Structural Biology Communications
- YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli
- (2019) Elsa Germain et al. Nature Communications
- Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors
- (2018) Ariel Talavera et al. Science Advances
- Regulation of (p)ppGpp hydrolysis by a conserved archetypal regulatory domain
- (2018) Séverin Ronneau et al. NUCLEIC ACIDS RESEARCH
- Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP inBacillus subtilis
- (2017) Jan Gundlach et al. Science Signaling
- Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP inBacillus subtilis
- (2017) Jan Gundlach et al. Science Signaling
- Ribosome-dependent activation of stringent control
- (2016) Alan Brown et al. NATURE
- The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis
- (2016) Stefan Arenz et al. NUCLEIC ACIDS RESEARCH
- ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules
- (2016) Haim Ashkenazy et al. NUCLEIC ACIDS RESEARCH
- Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone
- (2015) Wieland Steinchen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comprehensive Absolute Quantification of the Cytosolic Proteome ofBacillus subtilisby Data Independent, Parallel Fragmentation in Liquid Chromatography/Mass Spectrometry (LC/MSE)
- (2014) Jan Muntel et al. MOLECULAR & CELLULAR PROTEOMICS
- CBS domains: Ligand binding sites and conformational variability
- (2013) June Ereño-Orbea et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The ribosome triggers the stringent response by RelA via a highly distorted tRNA
- (2013) Xabier Agirrezabala et al. EMBO REPORTS
- MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
- (2013) K. Katoh et al. MOLECULAR BIOLOGY AND EVOLUTION
- Towards automated crystallographic structure refinement withphenix.refine
- (2012) Pavel V. Afonine et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Exploiting structure similarity in refinement: automated NCS and target-structure restraints inBUSTER
- (2012) Oliver S. Smart et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Positive allosteric feedback regulation of the stringent response enzyme RelA by its product
- (2012) Viktoriya Shyp et al. EMBO REPORTS
- c-di-AMP reports DNA integrity during sporulation in Bacillus subtilis
- (2011) Yaara Oppenheimer-Shaanan et al. EMBO REPORTS
- The RelA/SpoT Homolog (RSH) Superfamily: Distribution and Functional Evolution of ppGpp Synthetases and Hydrolases across the Tree of Life
- (2011) Gemma C. Atkinson et al. PLoS One
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Allostery and Intrinsic Disorder Mediate Transcription Regulation by Conditional Cooperativity
- (2010) Abel Garcia-Pino et al. CELL
- Analysis of Protein Conformation and Dynamics by Hydrogen/Deuterium Exchange MS
- (2009) John R. Engen ANALYTICAL CHEMISTRY
- The Significance of EXDD and RXKD Motif Conservation in Rel Proteins
- (2009) Mathew Sajish et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started