The RelA/SpoT Homolog (RSH) Superfamily: Distribution and Functional Evolution of ppGpp Synthetases and Hydrolases across the Tree of Life

Multispecific Recognition: Mechanism, Evolution, and Design

(2011) Ariel Erijman et al.   BIOCHEMISTRY

Phenotypic heterogeneity in mycobacterial stringent response

(2011) Sayantari Ghosh et al.   BMC Systems Biology

Linkage between the bacterial acid stress and stringent responses: the structure of the inducible lysine decarboxylase

(2011) Usheer Kanjee et al.   EMBO JOURNAL

Complementation ofRickettsia rickettsiiRelA/SpoT Restores a Nonlytic Plaque Phenotype

(2011) Tina R. Clark et al.   INFECTION AND IMMUNITY

The complex logic of stringent response regulation in Caulobacter crescentus: starvation signalling in an oligotrophic environment

(2011) Cara C. Boutte et al.   MOLECULAR MICROBIOLOGY

Signalling by the global regulatory molecule ppGpp in bacteria and chloroplasts of land plants

(2011) Y. Tozawa et al.   PLANT BIOLOGY

Single-molecule investigations of the stringent response machinery in living bacterial cells

(2011) B. P. English et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rickettsial evolution in the light of comparative genomics

(2010) Vicky Merhej et al.   BIOLOGICAL REVIEWS

ppGpp is the major source of growth rate control in E. coli

(2010) Katarzyna Potrykus et al.   ENVIRONMENTAL MICROBIOLOGY

Phylogeny of Gammaproteobacteria

(2010) K. P. Williams et al.   JOURNAL OF BACTERIOLOGY

Thermodynamic Characterization of ppGpp Binding to EF-G or IF2 and of Initiator tRNA Binding to Free IF2 in the Presence of GDP, GTP, or ppGpp

(2010) Vladimir A. Mitkevich et al.   JOURNAL OF MOLECULAR BIOLOGY

Chlamydia abortus YhbZ, a truncated Obg family GTPase, associates with the Escherichia coli large ribosomal subunit

(2010) Adam Polkinghorne et al.   MICROBIAL PATHOGENESIS

ppGpp Conjures Bacterial Virulence

(2010) Z. D. Dalebroux et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Evolution of Elongation Factor G and the Origins of Mitochondrial and Chloroplast Forms

(2010) G. C. Atkinson et al.   MOLECULAR BIOLOGY AND EVOLUTION

Cost of Unneeded Proteins in E. coli Is Reduced after Several Generations in Exponential Growth

(2010) Irit Shachrai et al.   MOLECULAR CELL

Fundamental limits on the suppression of molecular fluctuations

(2010) Ioannis Lestas et al.   NATURE

The evolution of gene duplications: classifying and distinguishing between models

(2010) Hideki Innan et al.   NATURE REVIEWS GENETICS

A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses

(2010) Dawei Sun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The endosymbiotic origin, diversification and fate of plastids

(2010) P. J. Keeling   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Structural Sources of Robustness in Biochemical Reaction Networks

(2010) G. Shinar et al.   SCIENCE

Intermediate Steps

(2010) D. P. Devos et al.   SCIENCE

The Compartmentalized Bacteria of the Planctomycetes-Verrucomicrobia-Chlamydiae Superphylum Have Membrane Coat-Like Proteins

(2010) Rachel Santarella-Mellwig et al.   PLOS BIOLOGY

Bacterial nucleotide-based second messengers

(2009) Christina Pesavento et al.   CURRENT OPINION IN MICROBIOLOGY

The Significance of EXDD and RXKD Motif Conservation in Rel Proteins

(2009) Mathew Sajish et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Degradation of ppGpp by Nudix Pyrophosphatase Modulates the Transition of Growth Phase in the BacteriumThermus thermophilus

(2009) Takushi Ooga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stringent response inVibrio cholerae: genetic analysis ofspoTgene function and identification of a novel (p)ppGpp synthetase gene

(2009) Bhabatosh Das et al.   MOLECULAR MICROBIOLOGY

ppGpp inhibits the activity of Escherichia coli DnaG primase

(2009) Monika Maciąg et al.   PLASMID

Phylogeny of prokaryotes: does it exist and why should we care?

(2009) Simonetta Gribaldo et al.   RESEARCH IN MICROBIOLOGY

A single molecule view of gene expression

(2009) Daniel R. Larson et al.   TRENDS IN CELL BIOLOGY

(p)ppGpp: Still Magical?

(2008) Katarzyna Potrykus et al.   Annual Review of Microbiology

Control of bacterial transcription, translation and replication by (p)ppGpp

(2008) Anjana Srivatsan et al.   CURRENT OPINION IN MICROBIOLOGY

Bacteria Possessing Two RelA/SpoT-Like Proteins Have Evolved a Specific Stringent Response Involving the Acyl Carrier Protein-SpoT Interaction

(2008) A. Battesti et al.   JOURNAL OF BACTERIOLOGY

Still Looking for the Magic Spot: The Crystallographically Defined Binding Site for ppGpp on RNA Polymerase Is Unlikely to Be Responsible for rRNA Transcription Regulation

(2008) Catherine E. Vrentas et al.   JOURNAL OF MOLECULAR BIOLOGY

Horizontal gene transfer in eukaryotic evolution

(2008) Patrick J. Keeling et al.   NATURE REVIEWS GENETICS

Positive Feedback and Noise Activate the Stringent Response Regulator Rel in Mycobacteria

(2008) Kamakshi Sureka et al.   PLoS One