A meet-up of two second messengers: the c-di-AMP receptor DarB controls (p)ppGpp synthesis in Bacillus subtilis

Cyclic di-AMP, a second messenger of primary importance: tertiary structures and binding mechanisms

(2020) Jin He et al.   NUCLEIC ACIDS RESEARCH

The C-Terminal RRM/ACT Domain Is Crucial for Fine-Tuning the Activation of ‘Long’ RelA-SpoT Homolog Enzymes by Ribosomal Complexes

(2020) Hiraku Takada et al.   Frontiers in Microbiology

The alarmones (p)ppGpp are part of the heat shock response of Bacillus subtilis

(2020) Heinrich Schäfer et al.   PLoS Genetics

Cyclic di-AMP Signaling in Bacteria

(2020) Jörg Stülke et al.   Annual Review of Microbiology

(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes

(2020) Bret N. Peterson et al.   mBio

Structural Basis for Regulation of the Opposing (p)ppGpp Synthetase and Hydrolase within the Stringent Response Orchestrator Rel

(2020) Patrick Pausch et al.   Cell Reports

The KupA and KupB proteins of Lactococcus lactis IL1403 are novel c-di-AMP receptor proteins responsible for potassium uptake

(2019) Ingrid M. Quintana et al.   JOURNAL OF BACTERIOLOGY

Sustained sensing in potassium homeostasis: Cyclic di-AMP controls potassium uptake by KimA at the levels of expression and activity

(2019) Jan Gundlach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Importance of potassium ions for ribosome structure and function revealed by long-wavelength X-ray diffraction

(2019) Alexey Rozov et al.   Nature Communications

Why Nature Chose Potassium

(2019) Antoine Danchin et al.   JOURNAL OF MOLECULAR EVOLUTION

YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli

(2019) Elsa Germain et al.   Nature Communications

A Delicate Connection: c-di-AMP Affects Cell Integrity by Controlling Osmolyte Transport

(2018) Fabian M. Commichau et al.   TRENDS IN MICROBIOLOGY

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Regulation of (p)ppGpp hydrolysis by a conserved archetypal regulatory domain

(2018) Séverin Ronneau et al.   NUCLEIC ACIDS RESEARCH

Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP inBacillus subtilis

(2017) Jan Gundlach et al.   Science Signaling

Control of potassium homeostasis is an essential function of the second messenger cyclic di-AMP inBacillus subtilis

(2017) Jan Gundlach et al.   Science Signaling

Construction and Analysis of Two Genome-Scale Deletion Libraries for Bacillus subtilis

(2017) Byoung-Mo Koo et al.   Cell Systems

The magic dance of the alarmones (p)ppGpp

(2016) Wieland Steinchen et al.   MOLECULAR MICROBIOLOGY

Cyclic di-AMP targets the cystathionine beta-synthase domain of the osmolyte transporter OpuC

(2016) TuAnh Ngoc Huynh et al.   MOLECULAR MICROBIOLOGY

Ribosome-dependent activation of stringent control

(2016) Alan Brown et al.   NATURE

ppGpp negatively impacts ribosome assembly affecting growth and antimicrobial tolerance in Gram-positive bacteria

(2016) Rebecca M. Corrigan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The second messenger c-di-AMP inhibits the osmolyte uptake system OpuC inStaphylococcus aureus

(2016) Christopher F. Schuster et al.   Science Signaling

Phosphotransferase-dependent accumulation of (p)ppGpp in response to glutamine deprivation in Caulobacter crescentus

(2016) Séverin Ronneau et al.   Nature Communications

The second messenger c-di-AMP inhibits the osmolyte uptake system OpuC inStaphylococcus aureus

(2016) Christopher F. Schuster et al.   Science Signaling

The PAMP c-di-AMP Is Essential for Listeria monocytogenes Growth in Rich but Not Minimal Media due to a Toxic Increase in (p)ppGpp

(2015) Aaron T. Whiteley et al.   Cell Host & Microbe

Sensory properties of the PIIsignalling protein family

(2015) Karl Forchhammer et al.   FEBS Journal

Cross-talk between Two Nucleotide-signaling Pathways inStaphylococcus aureus

(2015) Rebecca M. Corrigan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Essential Gene Involved in 16S rRNA Processing in Escherichia coli

(2015) Tatsuaki Kurata et al.   JOURNAL OF MOLECULAR BIOLOGY

A highly sensitive quantification method for the accumulation of alarmone ppGpp in Arabidopsis thaliana using UPLC-ESI-qMS/MS

(2015) Yuta Ihara et al.   JOURNAL OF PLANT RESEARCH

ComGA-RelA interaction and persistence in theBacillus subtilis K-state

(2015) Jeanette Hahn et al.   MOLECULAR MICROBIOLOGY

Recent functional insights into the role of (p)ppGpp in bacterial physiology

(2015) Vasili Hauryliuk et al.   NATURE REVIEWS MICROBIOLOGY

Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone

(2015) Wieland Steinchen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence

(2015) TuAnh Ngoc Huynh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cyclic Dinucleotide c-di-AMP Is an Allosteric Regulator of Metabolic Enzyme Function

(2014) Kamakshi Sureka et al.   CELL

Identification, Characterization, and Structure Analysis of the Cyclic di-AMP-binding PII-like Signal Transduction Protein DarA

(2014) Jan Gundlach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphotransferase protein EIIANtr interacts with SpoT, a key enzyme of the stringent response, in Ralstonia eutropha H16

(2014) K. Karstens et al.   MICROBIOLOGY-SGM

Comprehensive Absolute Quantification of the Cytosolic Proteome ofBacillus subtilisby Data Independent, Parallel Fragmentation in Liquid Chromatography/Mass Spectrometry (LC/MSE)

(2014) Jan Muntel et al.   MOLECULAR & CELLULAR PROTEOMICS

Riboswitches in eubacteria sense the second messenger c-di-AMP

(2013) James W Nelson et al.   Nature Chemical Biology

A Novel Factor Controlling Bistability in Bacillus subtilis: the YmdB Protein Affects Flagellin Expression and Biofilm Formation

(2011) C. Diethmaier et al.   JOURNAL OF BACTERIOLOGY

RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y

(2011) Martin Lehnik-Habrink et al.   MOLECULAR MICROBIOLOGY

YybT Is a Signaling Protein That Contains a Cyclic Dinucleotide Phosphodiesterase Domain and a GGDEF Domain with ATPase Activity

(2009) Feng Rao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stimulation of the potassium sensor KdpD kinase activity by interaction with the phosphotransferase protein IIANtrinEscherichia coli

(2009) Denise Lüttmann et al.   MOLECULAR MICROBIOLOGY