Defined Alginate Hydrogels Support Spinal Cord Organoid Derivation, Maturation, and Modeling of Spinal Cord Diseases

iPSC-derived myelinoids to study myelin biology of humans

(2022) Owen G. James et al.   DEVELOPMENTAL CELL

Production of human spinal-cord organoids recapitulating neural-tube morphogenesis

(2022) Ju-Hyun Lee et al.   Nature Biomedical Engineering

Multiscale Mechanobiology in Brain Physiology and Diseases

(2022) Anthony Procès et al.   Frontiers in Cell and Developmental Biology

More Than Mortar: Glia as Architects of Nervous System Development and Disease

(2021) Inês Lago-Baldaia et al.   Frontiers in Cell and Developmental Biology

Rapid and Efficient Generation of Myelinating Human Oligodendrocytes in Organoids

(2021) Mohammed R. Shaker et al.   Frontiers in Cellular Neuroscience

Actuation enhances patterning in human neural tube organoids

(2021) Abdel Rahman Abdel Fattah et al.   Nature Communications

Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions

(2021) João D. Pereira et al.   Nature Communications

Mechanotransduction assays for neural regeneration strategies: A focus on glial cells

(2021) Nicolas Marinval et al.   APL Bioengineering

Developing a mechanically matched decellularized spinal cord scaffold for the in situ matrix-based neural repair of spinal cord injury

(2021) Yuan-huan Ma et al.   BIOMATERIALS

Functional hydrogels as therapeutic tools for spinal cord injury: New perspectives on immunopharmacological interventions

(2021) Ciara M. Walsh et al.   PHARMACOLOGY & THERAPEUTICS

Towards organoid culture without Matrigel

(2021) Mark T. Kozlowski et al.   Communications Biology

Polymer Hydrogels to Guide Organotypic and Organoid Cultures

(2020) Valentina Magno et al.   ADVANCED FUNCTIONAL MATERIALS

Sliced Human Cortical Organoids for Modeling Distinct Cortical Layer Formation

(2020) Xuyu Qian et al.   Cell Stem Cell

Regenerative Medicine for Spinal Cord Injury: Focus on Stem Cells and Biomaterials

(2020) Simonetta Papa et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Organoid cultures of MELAS neural cells reveal hyperactive Notch signaling that impacts neurodevelopment

(2020) Winanto et al.   Cell Death & Disease

Synthetic alternatives to Matrigel

(2020) Elizabeth A. Aisenbrey et al.   Nature Reviews Materials

Human organoids: model systems for human biology and medicine

(2020) Jihoon Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies

(2020) Myungjin Jo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells

(2020) Keita Kajikawa et al.   Molecular Brain

Chemically Modified Biopolymers for the Formation of Biomedical Hydrogels

(2020) Victoria G. Muir et al.   CHEMICAL REVIEWS

Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids

(2019) Meghan M. Capeling et al.   Stem Cell Reports

Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures

(2019) Rebecca M. Marton et al.   NATURE NEUROSCIENCE

Pluripotent Stem Cell-Derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins

(2019) Hyosung Kim et al.   Stem Cell Reports

Disease modelling in human organoids

(2019) Madeline A. Lancaster et al.   Disease Models & Mechanisms

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

(2019) Daehwan Kim et al.   NATURE BIOTECHNOLOGY

Engineered materials for organoid systems

(2019) Michael J. Kratochvil et al.   Nature Reviews Materials

Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation

(2019) Qingsheng Liu et al.   Nature Communications

Computational-Based Design of Hydrogels with Predictable Mesh Properties

(2019) Kevin T. Campbell et al.   ACS Biomaterials-Science & Engineering

Translational Regenerative Therapies for Chronic Spinal Cord Injury

(2018) Kyriakos Dalamagkas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Growth of Epithelial Organoids in a Defined Hydrogel

(2018) Nicolas Broguiere et al.   ADVANCED MATERIALS

Generation and post-injury integration of human spinal cord neural stem cells

(2018) Hiromi Kumamaru et al.   NATURE METHODS

Induction of myelinating oligodendrocytes in human cortical spheroids

(2018) Mayur Madhavan et al.   NATURE METHODS

Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy

(2018) Jin Hui Hor et al.   Cell Death & Disease

Tissue mechanics regulate brain development, homeostasis and disease

(2017) J. Matthew Barnes et al.   JOURNAL OF CELL SCIENCE

A 3D printed microfluidic device for production of functionalized hydrogel microcapsules for culture and differentiation of human Neuronal Stem Cells (hNSC)

(2016) Kevin Alessandri et al.   LAB ON A CHIP

Designer matrices for intestinal stem cell and organoid culture

(2016) Nikolce Gjorevski et al.   NATURE

Neural tube morphogenesis in synthetic 3D microenvironments

(2016) Adrian Ranga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Induction of Cerebral Organoids From Human Induced Pluripotent Stem Cells Using a Chemically Defined Hydrogel and Defined Cell Culture Medium

(2016) Beth A. Lindborg et al.   Stem Cells Translational Medicine

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

(2015) Ovijit Chaudhuri et al.   NATURE MATERIALS

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Self-organizing optic-cup morphogenesis in three-dimensional culture

(2011) Mototsugu Eiraku et al.   NATURE

Alginate: Properties and biomedical applications

(2011) Kuen Yong Lee et al.   PROGRESS IN POLYMER SCIENCE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS

(2010) S.-C. Ling et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matrigel: A complex protein mixture required for optimal growth of cell culture

(2010) Chris S. Hughes et al.   PROTEOMICS

Modeling the controllable pH-responsive swelling and pore size of networked alginate based biomaterials

(2009) Ariel W. Chan et al.   BIOMATERIALS

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS