Developmental impacts of Nrf2 activation by dimethyl fumarate (DMF) in the developing zebrafish (Danio rerio) embryo

Redox Homeostasis in Pancreatic β-Cells: From Development to Failure

(2021) Štěpánka Benáková et al.   Antioxidants

Dimethyl Fumarate Reduces Hepatocyte Injury Following Paracetamol Exposure

(2021) Jose Meseguer-Ripolles et al.   iScience

NRF2 as a Therapeutic Target in Neurodegenerative Diseases

(2020) Mikah S. Brandes et al.   ASN Neuro

Seasonal changes in NRF2 antioxidant pathway regulates winter depression-like behavior

(2020) Tomoya Nakayama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulating glutathione thiol status alters pancreatic β-cell morphogenesis in the developing zebrafish (Danio rerio) embryo

(2020) Archit Rastogi et al.   Redox Biology

RNA-Seq provides new insights on the relative mRNA abundance of antioxidant components during mouse liver development

(2019) Kai Connie Wu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The prevalence of MS in the United States

(2019) Mitchell T. Wallin et al.   NEUROLOGY

Dimethyl fumarate, a two-edged drug: Current status and future directions

(2019) Nathaniel Edward Bennett Saidu et al.   MEDICINAL RESEARCH REVIEWS

Activators and Inhibitors of NRF2: A Review of Their Potential for Clinical Development

(2019) Natalia Robledinos-Antón et al.   Oxidative Medicine and Cellular Longevity

Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes

(2019) Karl E. Carlström et al.   Nature Communications

Mapping glutathione utilization in the developing zebrafish (Danio rerio) embryo

(2019) Archit Rastogi et al.   Redox Biology

Dimethyl Fumarate Controls the NRF2/DJ-1 Axis in Cancer Cells: Therapeutic Applications

(2017) Nathaniel Edward Bennett Saidu et al.   MOLECULAR CANCER THERAPEUTICS

Evidence of activation of the Nrf2 pathway in multiple sclerosis patients treated with delayed-release dimethyl fumarate in the Phase 3 DEFINE and CONFIRM studies

(2017) Sreeja Gopal et al.   Multiple Sclerosis Journal

Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase

(2017) Christina Hoffmann et al.   Oxidative Medicine and Cellular Longevity

Evidence of activation of the Nrf2 pathway in multiple sclerosis patients treated with delayed-release dimethyl fumarate in the Phase 3 DEFINE and CONFIRM studies

(2017) Sreeja Gopal et al.   Multiple Sclerosis Journal

The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo

(2017) Karilyn E. Sant et al.   Redox Biology

Oxidative stress in multiple sclerosis: Central and peripheral mode of action

(2016) Kim Ohl et al.   EXPERIMENTAL NEUROLOGY

The functional interactome of GSTP: A regulatory biomolecular network at the interface with the Nrf2 adaption response to oxidative stress

(2016) Desirée Bartolini et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Nrf2-dysregulation correlates with reduced synthesis and low glutathione levels in experimental autoimmune encephalomyelitis

(2016) Itzy E. Morales Pantoja et al.   JOURNAL OF NEUROCHEMISTRY

Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease

(2016) M. Ahuja et al.   JOURNAL OF NEUROSCIENCE

Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2

(2016) Ulf Schulze-Topphoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical proteomic map of dimethyl fumarate–sensitive cysteines in primary human T cells

(2016) Megan M. Blewett et al.   Science Signaling

Chemical proteomic map of dimethyl fumarate–sensitive cysteines in primary human T cells

(2016) Megan M. Blewett et al.   Science Signaling

Regulation of Ahr signaling by Nrf2 during development: Effects of Nrf2a deficiency on PCB126 embryotoxicity in zebrafish (Danio rerio)

(2015) Michelle E. Rousseau et al.   AQUATIC TOXICOLOGY

Glutathione during embryonic development

(2015) Jason M. Hansen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

p62 links autophagy and Nrf2 signaling

(2015) Tao Jiang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dimethyl Fumarate Protects Neural Stem/Progenitor Cells and Neurons from Oxidative Damage through Nrf2-ERK1/2 MAPK Pathway

(2015) Qin Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease

(2015) Géraldine Gentric et al.   JOURNAL OF CLINICAL INVESTIGATION

Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on KEAP1, NRF2 Activation, and Glutathione Depletion In Vitro

(2015) Melanie S. Brennan et al.   PLoS One

The Transcriptional Response to Oxidative Stress during Vertebrate Development: Effects of tert-Butylhydroquinone and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

(2014) Mark E. Hahn et al.   PLoS One

Glutathione redox dynamics and expression of glutathione-related genes in the developing embryo

(2013) Alicia R. Timme-Laragy et al.   FREE RADICAL BIOLOGY AND MEDICINE

Genetic Evidence of an Evolutionarily Conserved Role for Nrf2 in the Protection against Oxidative Stress

(2012) K. Mukaigasa et al.   MOLECULAR AND CELLULAR BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Nrf2b, Novel Zebrafish Paralog of Oxidant-responsive Transcription Factor NF-E2-related Factor 2 (NRF2)

(2011) Alicia R. Timme-Laragy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dimethylfumarate Inhibits Angiogenesis In Vitro and In Vivo: A Possible Role for Its Antipsoriatic Effect?

(2011) Melissa García-Caballero et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Protein S-glutathiolation: Redox-sensitive regulation of protein function

(2011) Bradford G. Hill et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Regulation of insulin secretion and reactive oxygen species production by free fatty acids in pancreatic islets

(2011) Maria Fernanda Graciano et al.   Islets

Reactive oxygen species and uncoupling protein 2 in pancreatic β-cell function

(2010) J. Pi et al.   DIABETES OBESITY & METABOLISM

Dimethylfumarate inhibits tumor cell invasion and metastasis by suppressing the expression and activities of matrix metalloproteinases in melanoma cells

(2009) Yuzuru Yamazoe et al.   CELL BIOLOGY INTERNATIONAL

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein S-glutathionylation: a regulatory device from bacteria to humans

(2009) Isabella Dalle-Donne et al.   TRENDS IN BIOCHEMICAL SCIENCES