The Transcriptional Response to Oxidative Stress during Vertebrate Development: Effects of tert-Butylhydroquinone and 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

Glutathione redox dynamics and expression of glutathione-related genes in the developing embryo

(2013) Alicia R. Timme-Laragy et al.   FREE RADICAL BIOLOGY AND MEDICINE

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Developmental Expression of the Nfe2-Related Factor (Nrf) Transcription Factor Family in the Zebrafish, Danio rerio

(2013) Larissa M. Williams et al.   PLoS One

Emerging applications for zebrafish as a model organism to study oxidative mechanisms and their roles in inflammation and vascular accumulation of oxidized lipids

(2012) Longhou Fang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of Nrf2 antioxidant defense in mitigating cadmium-induced oxidative stress in the olfactory system of zebrafish

(2012) Lu Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles

(2011) Abena S. Agyeman et al.   BREAST CANCER RESEARCH AND TREATMENT

FOXQ1 Regulates Epithelial-Mesenchymal Transition in Human Cancers

(2011) Y. Qiao et al.   CANCER RESEARCH

Forkhead Transcription Factor Foxq1 Promotes Epithelial–Mesenchymal Transition and Breast Cancer Metastasis

(2011) Haijun Zhang et al.   CANCER RESEARCH

HSF1-Dependent Upregulation of Hsp70 by Sulfhydryl-Reactive Inducers of the KEAP1/NRF2/ARE Pathway

(2011) Ying Zhang et al.   CHEMISTRY & BIOLOGY

Nrf2b, Novel Zebrafish Paralog of Oxidant-responsive Transcription Factor NF-E2-related Factor 2 (NRF2)

(2011) Alicia R. Timme-Laragy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Factor Erythroid 2-Related Factor 2 Facilitates Neuronal Glutathione Synthesis by Upregulating Neuronal Excitatory Amino Acid Transporter 3 Expression

(2011) C. Escartin et al.   JOURNAL OF NEUROSCIENCE

Tissue-Restricted Expression of Nrf2 and Its Target Genes in Zebrafish with Gene-Specific Variations in the Induction Profiles

(2011) Hitomi Nakajima et al.   PLoS One

Zebrafish embryos as an alternative to animal experiments—A commentary on the definition of the onset of protected life stages in animal welfare regulations

(2011) Uwe Strähle et al.   REPRODUCTIVE TOXICOLOGY

Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish

(2010) Jared V Goldstone et al.   BMC GENOMICS

FOXQ1 Is Overexpressed in Colorectal Cancer and Enhances Tumorigenicity and Tumor Growth

(2010) H. Kaneda et al.   CANCER RESEARCH

2,3,7,8-Tetrachlorodibenzo-p-dioxin UpregulatesFoxQ1bin Zebrafish Jaw Primordium

(2010) Antonio Planchart et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Reactive oxygen species: A radical role in development?

(2010) David Hernández-García et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system: a study using green fluorescent protein transgenic zebrafish

(2010) Tadayuki Tsujita et al.   GENES TO CELLS

Genome-Wide Analysis of Estrogen Receptor   DNA Binding and Tethering Mechanisms Identifies Runx1 as a Novel Tethering Factor in Receptor-Mediated Transcriptional Activation

(2010) J. D. Stender et al.   MOLECULAR AND CELLULAR BIOLOGY

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

(2010) Deepti Malhotra et al.   NUCLEIC ACIDS RESEARCH

ChIPing the cistrome of PXR in mouse liver

(2010) Julia Yue Cui et al.   NUCLEIC ACIDS RESEARCH

Dynamic Zebrafish Interactome Reveals Transcriptional Mechanisms of Dioxin Toxicity

(2010) Andrey Alexeyenko et al.   PLoS One

Saltatory ontogeny of fishes and sensitive early life stages for ecotoxicology tests

(2009) Scott E. Belanger et al.   AQUATIC TOXICOLOGY

The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research

(2009) Michelle R. Embry et al.   AQUATIC TOXICOLOGY

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice

(2009) Melinda S. Yates et al.   CARCINOGENESIS

Expression profiling of zebrafish sox9 mutants reveals that Sox9 is required for retinal differentiation

(2009) Hayato Yokoi et al.   DEVELOPMENTAL BIOLOGY

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of a screening assay to identify teratogenic and embryotoxic chemicals using the zebrafish embryo

(2009) Ingrid W.T. Selderslaghs et al.   REPRODUCTIVE TOXICOLOGY

Increased Nrf2 Activation in Livers from Keap1-Knockdown Mice Increases Expression of Cytoprotective Genes that Detoxify Electrophiles more than those that Detoxify Reactive Oxygen Species

(2009) Scott A. Reisman et al.   TOXICOLOGICAL SCIENCES

Antioxidant Responses and NRF2 in Synergistic Developmental Toxicity of PAHs in Zebrafish

(2009) Alicia R. Timme-Laragy et al.   TOXICOLOGICAL SCIENCES

Oxidative Stress in Developmental Origins of Disease: Teratogenesis, Neurodevelopmental Deficits, and Cancer

(2009) Peter G. Wells et al.   TOXICOLOGICAL SCIENCES

Cross-platform comparison of SYBR Green real-time PCR with TaqMan PCR, microarrays and other gene expression measurement technologies evaluated in the MicroArray Quality Control (MAQC) study

(2008) Emi Arikawa et al.   BMC GENOMICS

Impairment of gastric acid secretion and increase of embryonic lethality in Foxq1-deficient mice

(2008) W. Goering et al.   CYTOGENETIC AND GENOME RESEARCH

The susceptibility to vitiligo is associated with NF-E2-related factor2 (Nrf2) gene polymorphisms: a study on Chinese Han population

(2008) Cui-Ping Guan et al.   EXPERIMENTAL DERMATOLOGY

Expressional changes in the intracellular melanogenesis pathways and their possible role the pathogenesis of vitiligo

(2008) Külli Kingo et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Detection of Mercury in Aquatic Environments Using EPRE Reporter Zebrafish

(2008) Brandon W. Kusik et al.   MARINE BIOTECHNOLOGY

The Antioxidant Defense System Keap1-Nrf2 Comprises a Multiple Sensing Mechanism for Responding to a Wide Range of Chemical Compounds

(2008) M. Kobayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

HepG2/C3A cells respond to cysteine deprivation by induction of the amino acid deprivation/integrated stress response pathway

(2008) Jeong-In Lee et al.   PHYSIOLOGICAL GENOMICS

The in vivo gene expression signature of oxidative stress

(2008) Eun-Soo Han et al.   PHYSIOLOGICAL GENOMICS

Promoter analysis of TCDD-inducible genes in a thymic epithelial cell line indicates the potential for cell-specific transcription factor crosstalk in the AhR response

(2008) Markus Frericks et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish

(2008) Crystal Y. Usenko et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nrf2 signaling: An adaptive response pathway for protection against environmental toxic insults

(2007) W OSBURN et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH