Fat and not sugar as the determining factor for gut microbiota changes, obesity, and related metabolic disorders in mice

Dietary macronutrients and the gut microbiome: a precision nutrition approach to improve cardiometabolic health

(2022) Kelly M Jardon et al.   GUT

Gut microbiome and health: mechanistic insights

(2022) Willem M de Vos et al.   GUT

Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms

(2022) Patrice D. Cani et al.   Nature Reviews Gastroenterology & Hepatology

Diet, microbiota, and the mucus layer: The guardians of our health

(2022) Francesco Suriano et al.   Frontiers in Immunology

Integrative study of diet-induced mouse models of NAFLD identifies PPARα as a sexually dimorphic drug target

(2021) Sarra Smati et al.   GUT

Diet-induced obesity in animal models: points to consider and influence on metabolic markers

(2021) Mariana de Moura e Dias et al.   Diabetology & Metabolic Syndrome

Gut Microbiome of Indonesian Adults Associated with Obesity and Type 2 Diabetes: A Cross-Sectional Study in an Asian City, Yogyakarta

(2021) Phatthanaphong Therdtatha et al.   Microorganisms

Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin

(2021) Francesco Suriano et al.   Microbiome

Diet-Induced Models of Non-Alcoholic Fatty Liver Disease: Food for Thought on Sugar, Fat, and Cholesterol

(2021) James M. Eng et al.   Cells

Gut Microbiota and Host Metabolism: From Proof of Concept to Therapeutic Intervention

(2021) Patrice D. Cani et al.   Microorganisms

The Interplay between Insulin Resistance, Inflammation, Oxidative Stress, Base Excision Repair and Metabolic Syndrome in Nonalcoholic Fatty Liver Disease

(2021) Sylwia Ziolkowska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adipose tissue derived bacteria are associated with inflammation in obesity and type 2 diabetes

(2020) Lucas Massier et al.   GUT

The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic

(2020) Leiluo Geng et al.   Nature Reviews Endocrinology

Gut microbiome, endocrine control of gut barrier function and metabolic diseases

(2020) Marion Régnier et al.   JOURNAL OF ENDOCRINOLOGY

Adipose tissue in health and disease

(2020) Innocence Harvey et al.   Open Biology

Behavioral Feeding Circuit: Dietary Fat-Induced Effects of Inflammatory Mediators in the Hypothalamus

(2020) Kinning Poon   Frontiers in Endocrinology

Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis

(2019) Amandine Everard et al.   Nature Communications

Obesity: global epidemiology and pathogenesis

(2019) Matthias Blüher   Nature Reviews Endocrinology

Defining the role of Parasutterella, a previously uncharacterized member of the core gut microbiota

(2019) Tingting Ju et al.   ISME Journal

Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications

(2019) Michele Longo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study

(2019) Clara Depommier et al.   NATURE MEDICINE

Quantitative microbiome profiling disentangles inflammation- and bile duct obstruction-associated microbiota alterations across PSC/IBD diagnoses

(2019) Sara Vieira-Silva et al.   Nature Microbiology

Crosstalk network among multiple inflammatory mediators in liver fibrosis

(2019) Han-Jing Zhangdi et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Discrepant gut microbiota markers for the classification of obesity-related metabolic abnormalities

(2019) Qiang Zeng et al.   Scientific Reports

Dietary Fat, but Not Protein or Carbohydrate, Regulates Energy Intake and Causes Adiposity in Mice

(2018) Sumei Hu et al.   Cell Metabolism

Endoplasmic reticulum stress and development of insulin resistance in adipose, skeletal, liver, and foetoplacental tissue in diabesity

(2018) Roberto Villalobos-Labra et al.   MOLECULAR ASPECTS OF MEDICINE

Skeletal muscle inflammation and insulin resistance in obesity

(2017) Huaizhu Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypothalamic inflammation in obesity and metabolic disease

(2017) Alexander Jais et al.   JOURNAL OF CLINICAL INVESTIGATION

Quantitative microbiome profiling links gut community variation to microbial load

(2017) Doris Vandeputte et al.   NATURE

Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

(2017) Ruixin Liu et al.   NATURE MEDICINE

Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

(2017) Yan Zheng et al.   Nature Reviews Endocrinology

Adapting to obesity with adipose tissue inflammation

(2017) Shannon M. Reilly et al.   Nature Reviews Endocrinology

Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and Potential New Treatments

(2017) Hironori Kitade et al.   Nutrients

Economic Burden of Obesity: A Systematic Literature Review

(2017) Maximilian Tremmel et al.   International Journal of Environmental Research and Public Health

Dietary sugars, not lipids, drive hypothalamic inflammation

(2017) Yuanqing Gao et al.   Molecular Metabolism

Animal models of obesity in rodents. An integrative review

(2016) Melina Ribeiro Fernandes et al.   Acta Cirurgica Brasileira

FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver

(2016) Stephanie von Holstein-Rathlou et al.   Cell Metabolism

Rhubarb extract prevents hepatic inflammation induced by acute alcohol intake, an effect related to the modulation of the gut microbiota

(2016) Audrey M. Neyrinck et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Reactive Oxygen Species and Oxidative Stress in Obesity-Recent Findings and Empirical Approaches

(2016) Fiona McMurray et al.   Obesity

Metabolic syndrome: a closer look at the growing epidemic and its associated pathologies

(2014) S. O'Neill et al.   Obesity Reviews

Hypothalamic Inflammation Without Astrogliosis in Response to High Sucrose Intake Is Modulated by Neonatal Nutrition in Male Rats

(2013) Esther Fuente-Martín et al.   ENDOCRINOLOGY

High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase

(2013) Takuji Ishimoto et al.   HEPATOLOGY

Gut-derived lipopolysaccharide augments adipose macrophage accumulation but is not essential for impaired glucose or insulin tolerance in mice

(2012) Robert Caesar et al.   GUT

Structural resilience of the gut microbiota in adult mice under high-fat dietary perturbations

(2012) Chenhong Zhang et al.   ISME Journal

Adiposoft: automated software for the analysis of white adipose tissue cellularity in histological sections

(2012) Miguel Galarraga et al.   JOURNAL OF LIPID RESEARCH

Central nervous system control of metabolism

(2012) Martin G. Myers et al.   NATURE

Modified High-Sucrose Diet-Induced Abdominally Obese and Normal-Weight Rats Developed High Plasma Free Fatty Acid and Insulin Resistance

(2012) Li Cao et al.   Oxidative Medicine and Cellular Longevity

Endoplasmic reticulum stress, obesity and diabetes

(2011) Miriam Cnop et al.   TRENDS IN MOLECULAR MEDICINE

Differential Effects of High-carbohydrate and High-fat Diet Composition on Muscle Insulin Resistance in Rats

(2010) Mu-Ryun Chun et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

High-fat diet-induced obesity in animal models

(2010) Niloofar Hariri et al.   NUTRITION RESEARCH REVIEWS

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice

(2008) Mathieu Membrez et al.   FASEB JOURNAL

A core gut microbiome in obese and lean twins

(2008) Peter J. Turnbaugh et al.   NATURE