Modulation of intestinal immune cell responses by eubiotic or dysbiotic microbiota in inflammatory bowel diseases

Antibiotic-associated dysbiosis affects the ability of the gut microbiota to control intestinal inflammation upon fecal microbiota transplantation in experimental colitis models

(2021) Francesco Strati et al.   Microbiome

Dynamic properties of the intestinal ecosystem call for combination therapies, targeting inflammation and microbiota, in ulcerative colitis

(2021) Maarten van de Guchte et al.   GASTROENTEROLOGY

Synbiotic supplementation with prebiotic green banana resistant starch and probiotic Bacillus coagulans spores ameliorates gut inflammation in mouse model of inflammatory bowel diseases

(2020) Tanvi Shinde et al.   EUROPEAN JOURNAL OF NUTRITION

Immunological variables associated with clinical and endoscopic response to vedolizumab in patients with inflammatory bowel diseases

(2020) Marina Coletta et al.   Journal of Crohns & Colitis

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

(2020) Aonghus Lavelle et al.   Nature Reviews Gastroenterology & Hepatology

How Probiotics Affect the Microbiota

(2020) Grégoire Wieërs et al.   Frontiers in Cellular and Infection Microbiology

Fecal microbiota transplantation to maintain remission in Crohn’s disease: a pilot randomized controlled study

(2020) Harry Sokol et al.   Microbiome

Fungal Trans-kingdom Dynamics Linked to Responsiveness to Fecal Microbiota Transplantation (FMT) Therapy in Ulcerative Colitis

(2020) Irina Leonardi et al.   Cell Host & Microbe

Assessing the efficacy and safety of fecal microbiota transplantation and probiotic VSL#3 for active ulcerative colitis: A systematic review and meta-analysis

(2020) Xiaofei Dang et al.   PLoS One

The Role of Gut Microbiota Biomodulators on Mucosal Immunity and Intestinal Inflammation

(2020) Chiara Amoroso et al.   Cells

Microbial therapeutics for acute colitis based on genetically modified Lactococcus lactis hypersecreting IL-1Ra in mice

(2020) Fu Namai et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Efficient treatment of a preclinical inflammatory bowel disease model with engineered bacteria

(2020) Szilamer Ferenczi et al.   Molecular Therapy-Methods & Clinical Development

Bifidobacterium infantis Induces Protective Colonic PD-L1 and Foxp3 Regulatory T Cells in an Acute Murine Experimental Model of Inflammatory Bowel Disease

(2019) Linyan Zhou et al.   Gut and Liver

Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice

(2019) Graham J. Britton et al.   IMMUNITY

Effect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis

(2019) Samuel P. Costello et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Effects of synbiotic therapy in mild-to-moderately active ulcerative colitis: A randomized placebo-controlled study

(2019) Hulya Kamarli Altun et al.   Turkish Journal of Gastroenterology

Neutrophil Extracellular Traps Sustain Inflammatory Signals in Ulcerative Colitis

(2019) Vincenzo Dinallo et al.   Journal of Crohns & Colitis

Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis

(2019) Lasha Gogokhia et al.   Cell Host & Microbe

The Integrative Human Microbiome Project

(2019)   NATURE

Synbiotic Supplementation Containing Whole Plant Sugar Cane Fibre and Probiotic Spores Potentiates Protective Synergistic Effects in Mouse Model of IBD

(2019) Tanvi Shinde et al.   Nutrients

Fecal Microbiota Transplantation Controls Murine Chronic Intestinal Inflammation by Modulating Immune Cell Functions and Gut Microbiota Composition

(2019) Burrello et al.   Cells

Fecal microbiota transplantation for ulcerative colitis: a prospective clinical study

(2019) Yan Tian et al.   BMC GASTROENTEROLOGY

Introduction of anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases: a population-based interrupted time series study

(2019) Sanjay K Murthy et al.   GUT

Targeting immune cell circuits and trafficking in inflammatory bowel disease

(2019) Markus F. Neurath   NATURE IMMUNOLOGY

Microbial genes and pathways in inflammatory bowel disease

(2019) Melanie Schirmer et al.   NATURE REVIEWS MICROBIOLOGY

Differential genetic and functional background in inflammatory bowel disease phenotypes of a Greek population: a systems bioinformatics approach

(2019) Maria Gazouli et al.   Gut Pathogens

Alleviation of Intestinal Inflammation by Oral Supplementation With 2-Fucosyllactose in Mice

(2019) Thomas Grabinger et al.   Frontiers in Microbiology

Manipulating resident microbiota to enhance regulatory immune function to treat inflammatory bowel diseases

(2019) Yoshiyuki Mishima et al.   JOURNAL OF GASTROENTEROLOGY

Immunological mechanisms underpinning faecal microbiota transplantation for the treatment of inflammatory bowel disease

(2019) M. N. Quraishi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Interrogating host immunity to predict treatment response in inflammatory bowel disease

(2019) Jonathan L. Digby-Bell et al.   Nature Reviews Gastroenterology & Hepatology

Dietary Fiber Pectin Ameliorates Experimental Colitis in a Neutral Sugar Side Chain-Dependent Manner

(2019) Keita Ishisono et al.   Frontiers in Immunology

Modern management of perianal fistulas in Crohn’s disease: future directions

(2018) Paulo Gustavo Kotze et al.   GUT

Pathogenicity of In Vivo Generated Intestinal Th17 Lymphocytes is IFNγ Dependent

(2018) Giulia Nizzoli et al.   Journal of Crohns & Colitis

New treatment options for inflammatory bowel diseases

(2018) Bram Verstockt et al.   JOURNAL OF GASTROENTEROLOGY

Polysaccharide of Hericium erinaceus attenuates colitis in C57BL/6 mice via regulation of oxidative stress, inflammation-related signaling pathways and modulating the composition of the gut microbiota

(2018) Yilin Ren et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Simultaneous Amelioratation of Colitis and Liver Injury in Mice by Bifidobacterium longum LC67 and Lactobacillus plantarum LC27

(2018) Se-Eun Jang et al.   Scientific Reports

Mechanistic Insights in the Success of Fecal Microbiota Transplants for the Treatment of Clostridium difficile Infections

(2018) Amoe Baktash et al.   Frontiers in Microbiology

The Administration of Escherichia coli Nissle 1917 Ameliorates Development of DSS-Induced Colitis in Mice

(2018) Alba Rodríguez-Nogales et al.   Frontiers in Pharmacology

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

(2018) Niv Zmora et al.   CELL

Metagenome analysis of Russian and Georgian Pyophage cocktails and a placebo-controlled safety trial of single phage versus phage cocktail in healthy Staphylococcus aureus carriers

(2018) Shawna McCallin et al.   ENVIRONMENTAL MICROBIOLOGY

A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model

(2018) Sadia Kanwal et al.   Nutrients

Response to Fungal Dysbiosis by Gut-Resident CX3CR1+ Mononuclear Phagocytes Aggravates Allergic Airway Disease

(2018) Xin Li et al.   Cell Host & Microbe

Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells

(2018) Claudia Burrello et al.   Nature Communications

Adherent-invasiveEscherichia coliin inflammatory bowel disease

(2017) Carolina Palmela et al.   GUT

Single Delivery of High-Diversity Fecal Microbiota Preparation by Colonoscopy Is Safe and Effective in Increasing Microbial Diversity in Active Ulcerative Colitis

(2017) Vinita Jacob et al.   INFLAMMATORY BOWEL DISEASES

Novel therapeutic targets for inflammatory bowel disease

(2017) Marjorie Argollo et al.   JOURNAL OF AUTOIMMUNITY

Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial

(2017) Sudarshan Paramsothy et al.   LANCET

Pathomechanisms of Oxidative Stress in Inflammatory Bowel Disease and Potential Antioxidant Therapies

(2017) Tian Tian et al.   Oxidative Medicine and Cellular Longevity

Effects of Probiotics, Prebiotics, and Synbiotics on Human Health

(2017) et al.   Nutrients

Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota

(2017) Chen Diling et al.   Oncotarget

Lactobacillus fermentum IM12 attenuates inflammation in mice by inhibiting NF-κB-STAT3 signalling pathway

(2017) S.-M. Lim et al.   Beneficial Microbes

Next-generation probiotics: the spectrum from probiotics to live biotherapeutics

(2017) Paul W. O’Toole et al.   Nature Microbiology

Reduced Abundance of Butyrate-Producing Bacteria Species in the Fecal Microbial Community in Crohn's Disease

(2016) Kenichiro Takahashi et al.   DIGESTION

Protease inhibition as new therapeutic strategy for GI diseases

(2016) Nathalie Vergnolle   GUT

The role of neutrophils and NETosis in autoimmune and renal diseases

(2016) Sarthak Gupta et al.   Nature Reviews Nephrology

Role and mechanisms of action ofEscherichia coliNissle 1917 in the maintenance of remission in ulcerative colitis patients: An update

(2016) Franco Scaldaferri et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Role of regulatory T cell in the pathogenesis of inflammatory bowel disease

(2016) Akiko Yamada et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Role of antibiotics for treatment of inflammatory bowel disease

(2016) Orna Nitzan   WORLD JOURNAL OF GASTROENTEROLOGY

Doxycycline, metronidazole and isotretinoin: Do they modify microRNA/mRNA expression profiles and function in murine T-cells?

(2016) Eugenia Becker et al.   Scientific Reports

Review article: the potential mechanisms of action of rifaximin in the management of inflammatory bowel diseases

(2015) R. B. Sartor   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled Trial

(2015) Paul Moayyedi et al.   GASTROENTEROLOGY

Findings From a Randomized Controlled Trial of Fecal Transplantation for Patients With Ulcerative Colitis

(2015) Noortje G. Rossen et al.   GASTROENTEROLOGY

Probiotics, prebiotics and synbiotics- a review

(2015) Kavita. R. Pandey et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

The Probiotic Mixture VSL#3 Has Differential Effects on Intestinal Immune Parameters in Healthy Female BALB/c and C57BL/6 Mice

(2015) Rob Mariman et al.   JOURNAL OF NUTRITION

Sphingolipids from a Symbiotic Microbe Regulate Homeostasis of Host Intestinal Natural Killer T Cells

(2014) Dingding An et al.   CELL

Protective mucosal immunity mediated by epithelial CD1d and IL-10

(2014) Torsten Olszak et al.   NATURE

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens

(2014) Yi Yang et al.   NATURE

Fluctuations in butyrate-producing bacteria in ulcerative colitis patients of North India

(2013) Reena Kumari   WORLD JOURNAL OF GASTROENTEROLOGY

In vitrofermentation of grape seed flavan-3-ol fractions by human faecal microbiota: changes in microbial groups and phenolic metabolites

(2012) Carolina Cueva et al.   FEMS MICROBIOLOGY ECOLOGY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Genetic Evidence Supporting the Association of Protease and Protease Inhibitor Genes with Inflammatory Bowel Disease: A Systematic Review

(2011) Isabelle Cleynen et al.   PLoS One

46 A Phase 2a Randomized Placebo-Controlled Double-Blind Multi-Center Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of AG011 in Patients With Moderately Active Ulcerative Colitis

(2010) Severine Vermeire et al.   GASTROENTEROLOGY

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Interleukin-21 triggers effector cell responses in the gut

(2010) Daniela De Nitto   WORLD JOURNAL OF GASTROENTEROLOGY

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

16S rRNA gene sequence-based analysis of clostridia related to conversion of germfree mice to the normal state

(2009) Y. Momose et al.   JOURNAL OF APPLIED MICROBIOLOGY

Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis

(2009) K Vandenbroucke et al.   Mucosal Immunology

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE