Role of regulatory T cell in the pathogenesis of inflammatory bowel disease

Developing in vitro expanded CD45RA+regulatory T cells as an adoptive cell therapy for Crohn's disease

(2015) James B Canavan et al.   GUT

Chemokine receptor CCR7 regulates the intestinal TH 1/TH 17/Treg balance during Crohnˈs-like murine ileitis

(2015) Eóin N. McNamee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Epithelial-derived IL-18 regulates Th17 cell differentiation and Foxp3+ Treg cell function in the intestine

(2015) O J Harrison et al.   Mucosal Immunology

Microbiota and Mucosal Immunity in Amphibians

(2015) Bruno M. Colombo et al.   Frontiers in Immunology

Inflammatory Bowel Disease as a Model for Translating the Microbiome

(2014) Curtis Huttenhower et al.   IMMUNITY

Inflammatory bowel disease

(2014) Daniele Corridoni et al.   IMMUNOLOGY LETTERS

Comprehensive Intestinal T Helper Cell Profiling Reveals Specific Accumulation of IFN-γ+IL-17+Coproducing CD4+ T Cells in Active Inflammatory Bowel Disease

(2014) Anna-Maria Globig et al.   INFLAMMATORY BOWEL DISEASES

Development of Inflammatory Bowel Disease in Long-Evans Cinnamon Rats Based on CD4+CD25+Foxp3+ Regulatory T Cell Dysfunction

(2014) N. Ishimaru et al.   JOURNAL OF IMMUNOLOGY

Transient Local Depletion of Foxp3+ Regulatory T Cells during Recovery from Colitis via Fas/Fas Ligand-Induced Death

(2014) C. Reardon et al.   JOURNAL OF IMMUNOLOGY

STAT4 Isoforms Differentially Regulate Th1 Cytokine Production and the Severity of Inflammatory Bowel Disease

(2014) J. T. O'Malley et al.   JOURNAL OF IMMUNOLOGY

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

(2014) K. G. Lassen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD4CD8αα Lymphocytes, A Novel Human Regulatory T Cell Subset Induced by Colonic Bacteria and Deficient in Patients with Inflammatory Bowel Disease

(2014) Guillaume Sarrabayrouse et al.   PLOS BIOLOGY

Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome

(2013) Dan Knights et al.   GUT

Induced and Natural Regulatory T Cells in the Development of Inflammatory Bowel Disease

(2013) Christopher G. Mayne et al.   INFLAMMATORY BOWEL DISEASES

Increased Prevalence of Circulating Novel IL-17 Secreting Foxp3 Expressing CD4+ T Cells and Defective Suppressive Function of Circulating Foxp3+ Regulatory Cells Support Plasticity Between Th17 and Regulatory T Cells in Inflammatory Bowel Disease Patients

(2013) Aito Ueno et al.   INFLAMMATORY BOWEL DISEASES

New targets for mucosal healing and therapy in inflammatory bowel diseases

(2013) M F Neurath   Mucosal Immunology

Regulatory T cells in nonlymphoid tissues

(2013) Dalia Burzyn et al.   NATURE IMMUNOLOGY

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

TGF-β Signalling Is Required for CD4+ T Cell Homeostasis But Dispensable for Regulatory T Cell Function

(2013) Anna Śledzińska et al.   PLOS BIOLOGY

Deletion of Foxp3+ regulatory T cells in genetically targeted mice supports development of intestinal inflammation

(2012) Franziska Boehm et al.   BMC GASTROENTEROLOGY

Nod-like receptors in the control of intestinal inflammation

(2012) Stephen J Rubino et al.   CURRENT OPINION IN IMMUNOLOGY

The TCR Repertoires of Regulatory and Conventional T Cells Specific for the Same Foreign Antigen Are Distinct

(2012) L. M. Relland et al.   JOURNAL OF IMMUNOLOGY

B Lymphocyte-Induced Maturation Protein-1 Contributes to Intestinal Mucosa Homeostasis by Limiting the Number of IL-17-Producing CD4+ T Cells

(2012) S. Salehi et al.   JOURNAL OF IMMUNOLOGY

Crohn's disease

(2012) Daniel C Baumgart et al.   LANCET

Tregs are dysfunctional in vivo in a spontaneous murine model of Crohn's disease

(2012) D Ishikawa et al.   Mucosal Immunology

Altered generation of induced regulatory T cells in the FVB.mdr1a−/− mouse model of colitis

(2012) S M Tanner et al.   Mucosal Immunology

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

CCR7 with S1P1 Signaling through AP-1 for Migration of Foxp3+ Regulatory T-Cells Controls Autoimmune Exocrinopathy

(2011) Naozumi Ishimaru et al.   AMERICAN JOURNAL OF PATHOLOGY

Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide

(2011) E. M. Fernandez et al.   GUT

Apoptosis of regulatory T lymphocytes is increased in chronic inflammatory bowel disease and reversed by anti-TNF  treatment

(2011) C. Veltkamp et al.   GUT

It Takes Two to Tango

(2011) Angelina B. Bilate et al.   IMMUNITY

A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity

(2011) Dipica Haribhai et al.   IMMUNITY

Oral tolerance

(2011) Howard L. Weiner et al.   IMMUNOLOGICAL REVIEWS

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis

(2011) Gianna Elena Hammer et al.   NATURE IMMUNOLOGY

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microbiotal influence on T cell subset development

(2011) Koji Atarashi et al.   SEMINARS IN IMMUNOLOGY

Induction of Treg cells in the mouse colonic mucosa: A central mechanism to maintain host–microbiota homeostasis

(2011) Takeshi Tanoue et al.   SEMINARS IN IMMUNOLOGY

Characterization of Interleukin-17–Producing Regulatory T Cells in Inflamed Intestinal Mucosa From Patients With Inflammatory Bowel Diseases

(2010) Zaruhi Hovhannisyan et al.   GASTROENTEROLOGY

T Regulatory Cells Maintain Intestinal Homeostasis by Suppressing γδ T Cells

(2010) Sung-Gyoo Park et al.   IMMUNITY

Reciprocal changes of Foxp3 expression in blood and intestinal mucosa in IBD patients responding to infliximab†

(2010) Zhe Li et al.   INFLAMMATORY BOWEL DISEASES

Intestinal growth factors: Potential use in the treatment of inflammatory bowel disease and their role in mucosal healing

(2010) Kumar Krishnan et al.   INFLAMMATORY BOWEL DISEASES

Therapy with anti-TNFα antibody enhances number and function of Foxp3+ regulatory T cells in inflammatory bowel diseases

(2010) Gilles Boschetti et al.   INFLAMMATORY BOWEL DISEASES

The impact of the microbiota on the pathogenesis of IBD: lessons from mouse infection models

(2010) Sandra Nell et al.   NATURE REVIEWS MICROBIOLOGY

In Situ Patrolling of Regulatory T Cells Is Essential for Protecting Autoimmune Exocrinopathy

(2010) Naozumi Ishimaru et al.   PLoS One

Genomic definition of multiple ex vivo regulatory T cell subphenotypes

(2010) M. Feuerer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Mouse models of intestinal inflammation as tools to understand the pathogenesis of inflammatory bowel disease

(2009) Holm H. Uhlig et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T Cells Reinforce Intestinal Homeostasis

(2009) Michael J. Barnes et al.   IMMUNITY

Control of Regulatory T Cell Lineage Commitment and Maintenance

(2009) Steven Z. Josefowicz et al.   IMMUNITY

Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease

(2009) Nicola Eastaff-Leung et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Commensal DNA Limits Regulatory T Cell Conversion and Is a Natural Adjuvant of Intestinal Immune Responses

(2008) Jason A. Hall et al.   IMMUNITY

The p50 Subunit of NF- B Is Critical for In Vivo Clearance of the Noninvasive Enteric Pathogen Citrobacter rodentium

(2008) A. Dennis et al.   INFECTION AND IMMUNITY

Galectin-2 and -4, but not Galectin-1, promote intestinal epithelial wound healing in vitro through a TGF-beta-independent mechanism

(2008) Daniela Paclik et al.   INFLAMMATORY BOWEL DISEASES

CD4+CD25+ regulatory T cells in the small intestinal lamina propria show an effector/memory phenotype

(2008) Z. Guo et al.   INTERNATIONAL IMMUNOLOGY

CD4+T Cells Transfer Resistance Against Citrobacter rodentium-Induced Infectious Colitis by Induction of Th 1 Immunity

(2008) T. W. Spahn et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Epithelial restitution and wound healing in inflammatory bowel disease

(2008) Andreas Sturm et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Aberrant Mucin Assembly in Mice Causes Endoplasmic Reticulum Stress and Spontaneous Inflammation Resembling Ulcerative Colitis

(2008) Chad K Heazlewood et al.   PLOS MEDICINE

MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis

(2007) D. L. Gibson et al.   CELLULAR MICROBIOLOGY