The Role of Gut Microbiota Biomodulators on Mucosal Immunity and Intestinal Inflammation

Assessment of serum cytokines predicts clinical and endoscopic outcomes to vedolizumab in ulcerative colitis patients

(2020) Lorenzo Bertani et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Synbiotic supplementation with prebiotic green banana resistant starch and probiotic Bacillus coagulans spores ameliorates gut inflammation in mouse model of inflammatory bowel diseases

(2020) Tanvi Shinde et al.   EUROPEAN JOURNAL OF NUTRITION

c9, t11, c15-CLNA and c9, t11, t15-CLNA from Lactobacillus plantarum ZS2058 Ameliorate DSS-Induced Colitis in Mice

(2020) Qing REN et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Immunological variables associated with clinical and endoscopic response to vedolizumab in patients with inflammatory bowel diseases

(2020) Marina Coletta et al.   Journal of Crohns & Colitis

OP09 Immunomodulatory mechanisms of faecal microbiota transplantation are associated with clinical response in ulcerative colitis: early results from STOP-Colitis

(2020) M N Quraishi et al.   Journal of Crohns & Colitis

Pathway paradigms revealed from the genetics of inflammatory bowel disease

(2020) Daniel B. Graham et al.   NATURE

Gut microbiota-derived metabolites as key actors in inflammatory bowel disease

(2020) Aonghus Lavelle et al.   Nature Reviews Gastroenterology & Hepatology

Muscadine grapes (Vitis rotundifolia) and dealcoholized muscadine wine alleviated symptoms of colitis and protected against dysbiosis in mice exposed to dextran sulfate sodium

(2020) Ruiqi Li et al.   Journal of Functional Foods

How Probiotics Affect the Microbiota

(2020) Grégoire Wieërs et al.   Frontiers in Cellular and Infection Microbiology

Fecal microbiota transplantation to maintain remission in Crohn’s disease: a pilot randomized controlled study

(2020) Harry Sokol et al.   Microbiome

Fungal Trans-kingdom Dynamics Linked to Responsiveness to Fecal Microbiota Transplantation (FMT) Therapy in Ulcerative Colitis

(2020) Irina Leonardi et al.   Cell Host & Microbe

Assessing the efficacy and safety of fecal microbiota transplantation and probiotic VSL#3 for active ulcerative colitis: A systematic review and meta-analysis

(2020) Xiaofei Dang et al.   PLoS One

On-Treatment Decrease of Serum Interleukin-6 as a Predictor of Clinical Response to Biologic Therapy in Patients with Inflammatory Bowel Diseases

(2020) Gian Paolo Caviglia et al.   Journal of Clinical Medicine

Bifidobacterium infantis Induces Protective Colonic PD-L1 and Foxp3 Regulatory T Cells in an Acute Murine Experimental Model of Inflammatory Bowel Disease

(2019) Linyan Zhou et al.   Gut and Liver

Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice

(2019) Graham J. Britton et al.   IMMUNITY

Effect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis

(2019) Samuel P. Costello et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Innate Lymphoid Cells: A Link between the Nervous System and Microbiota in Intestinal Networks

(2019) Lin Han et al.   MEDIATORS OF INFLAMMATION

Effects of synbiotic therapy in mild-to-moderately active ulcerative colitis: A randomized placebo-controlled study

(2019) Hulya Kamarli Altun et al.   Turkish Journal of Gastroenterology

Neutrophil Extracellular Traps Sustain Inflammatory Signals in Ulcerative Colitis

(2019) Vincenzo Dinallo et al.   Journal of Crohns & Colitis

P762 Onset of inflammatory bowel disease during treatment with secukinumab: Can anti-IL-17A be a trigger for inflammatory bowel disease?

(2019) R Rodríguez Moncada et al.   Journal of Crohns & Colitis

P655 Microencapsulated Sodium Butyrate significantly modifies the microbiota in patients with inflammatory bowel disease mimicking prebiotic activity and proving effects on the treatment of the disease

(2019) S Facchin et al.   Journal of Crohns & Colitis

The Integrative Human Microbiome Project

(2019)   NATURE

Synbiotic Supplementation Containing Whole Plant Sugar Cane Fibre and Probiotic Spores Potentiates Protective Synergistic Effects in Mouse Model of IBD

(2019) Tanvi Shinde et al.   Nutrients

Fecal Microbiota Transplantation Controls Murine Chronic Intestinal Inflammation by Modulating Immune Cell Functions and Gut Microbiota Composition

(2019) Burrello et al.   Cells

Fecal microbiota transplantation for ulcerative colitis: a prospective clinical study

(2019) Yan Tian et al.   BMC GASTROENTEROLOGY

Inflammatory Bowel Disease Onset During Secukinumab Treatment: Real Concern or Just an Expression of Dysregulated Immune Response?

(2019) Walter Fries et al.   CLINICAL DRUG INVESTIGATION

Introduction of anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases: a population-based interrupted time series study

(2019) Sanjay K Murthy et al.   GUT

Targeting immune cell circuits and trafficking in inflammatory bowel disease

(2019) Markus F. Neurath   NATURE IMMUNOLOGY

Microbial genes and pathways in inflammatory bowel disease

(2019) Melanie Schirmer et al.   NATURE REVIEWS MICROBIOLOGY

Differential genetic and functional background in inflammatory bowel disease phenotypes of a Greek population: a systems bioinformatics approach

(2019) Maria Gazouli et al.   Gut Pathogens

Postbiotic L. plantarum RG14 improves ruminal epithelium growth, immune status and upregulates the intestinal barrier function in post-weaning lambs

(2019) Wan Ibrahim Izuddin et al.   Scientific Reports

Flagellin hypervariable region determines symbiotic properties of commensal Escherichia coli strains

(2019) Alex Steimle et al.   PLOS BIOLOGY

Alleviation of Intestinal Inflammation by Oral Supplementation With 2-Fucosyllactose in Mice

(2019) Thomas Grabinger et al.   Frontiers in Microbiology

Manipulating resident microbiota to enhance regulatory immune function to treat inflammatory bowel diseases

(2019) Yoshiyuki Mishima et al.   JOURNAL OF GASTROENTEROLOGY

Postbiotics: facts and open questions. A position paper on the need for a consensus definition

(2019) M.C. Collado et al.   Beneficial Microbes

Immunological mechanisms underpinning faecal microbiota transplantation for the treatment of inflammatory bowel disease

(2019) M. N. Quraishi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

An orally administered butyrate-releasing xylan derivative reduces inflammation in dextran sulphate sodium-induced murine colitis

(2019) Zhengqi Zha et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Interrogating host immunity to predict treatment response in inflammatory bowel disease

(2019) Jonathan L. Digby-Bell et al.   Nature Reviews Gastroenterology & Hepatology

Attenuation of DSS induced colitis by Dictyophora indusiata polysaccharide (DIP) via modulation of gut microbiota and inflammatory related signaling pathways

(2019) Sadia Kanwal et al.   Journal of Functional Foods

Immunomodulatory Effect of Gut Microbiota-Derived Bioactive Peptides on Human Immune System from Healthy Controls and Patients with Inflammatory Bowel Disease

(2019) Samuel Fernández-Tomé et al.   Nutrients

Immunomodulating Activity and Therapeutic Effects of Short Chain Fatty Acids and Tryptophan Post-biotics in Inflammatory Bowel Disease

(2019) Edda Russo et al.   Frontiers in Immunology

Adalimumab Therapy Improves Intestinal Dysbiosis in Crohn's Disease

(2019) Davide Giuseppe Ribaldone et al.   Journal of Clinical Medicine

Dietary Fiber Pectin Ameliorates Experimental Colitis in a Neutral Sugar Side Chain-Dependent Manner

(2019) Keita Ishisono et al.   Frontiers in Immunology

Interactions Between Diet and the Intestinal Microbiota Alter Intestinal Permeability and Colitis Severity in Mice

(2018) Sean R. Llewellyn et al.   GASTROENTEROLOGY

Modern management of perianal fistulas in Crohn’s disease: future directions

(2018) Paulo Gustavo Kotze et al.   GUT

Faecalibacterium prausnitzii Produces Butyrate to Maintain Th17/Treg Balance and to Ameliorate Colorectal Colitis by Inhibiting Histone Deacetylase 1

(2018) Lixing Zhou et al.   INFLAMMATORY BOWEL DISEASES

Pathogenicity of In Vivo Generated Intestinal Th17 Lymphocytes is IFNγ Dependent

(2018) Giulia Nizzoli et al.   Journal of Crohns & Colitis

New treatment options for inflammatory bowel diseases

(2018) Bram Verstockt et al.   JOURNAL OF GASTROENTEROLOGY

Polysaccharide of Hericium erinaceus attenuates colitis in C57BL/6 mice via regulation of oxidative stress, inflammation-related signaling pathways and modulating the composition of the gut microbiota

(2018) Yilin Ren et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Supplementation of p40, a Lactobacillus rhamnosus GG-derived protein, in early life promotes epidermal growth factor receptor-dependent intestinal development and long-term health outcomes

(2018) Xi Shen et al.   Mucosal Immunology

L. plantarum WCFS1 enhances Treg frequencies by activating DCs even in absence of sampling of bacteria in the Peyer Patches

(2018) Miriam Bermudez-Brito et al.   Scientific Reports

Simultaneous Amelioratation of Colitis and Liver Injury in Mice by Bifidobacterium longum LC67 and Lactobacillus plantarum LC27

(2018) Se-Eun Jang et al.   Scientific Reports

Mechanistic Insights in the Success of Fecal Microbiota Transplants for the Treatment of Clostridium difficile Infections

(2018) Amoe Baktash et al.   Frontiers in Microbiology

The Administration of Escherichia coli Nissle 1917 Ameliorates Development of DSS-Induced Colitis in Mice

(2018) Alba Rodríguez-Nogales et al.   Frontiers in Pharmacology

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

(2018) Niv Zmora et al.   CELL

A Polysaccharide Isolated from Dictyophora indusiata Promotes Recovery from Antibiotic-Driven Intestinal Dysbiosis and Improves Gut Epithelial Barrier Function in a Mouse Model

(2018) Sadia Kanwal et al.   Nutrients

New Onset of Inflammatory Bowel Disease in Three Patients Undergoing IL-17A Inhibitor Secukinumab

(2018) Marta Vernero et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Response to Fungal Dysbiosis by Gut-Resident CX3CR1+ Mononuclear Phagocytes Aggravates Allergic Airway Disease

(2018) Xin Li et al.   Cell Host & Microbe

The clinical effects of probiotics for inflammatory bowel disease

(2018) Kai Jia et al.   MEDICINE

Mechanism and therapeutic effects of Saccharomyces boulardii on experimental colitis in mice

(2018) Huan Zhou et al.   Molecular Medicine Reports

Peptides encrypted in the human intestinal microbial-exoproteome as novel biomarkers and immunomodulatory compounds in the gastrointestinal tract

(2018) Samuel Fernández-Tomé et al.   Journal of Functional Foods

Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells

(2018) Claudia Burrello et al.   Nature Communications

Single Delivery of High-Diversity Fecal Microbiota Preparation by Colonoscopy Is Safe and Effective in Increasing Microbial Diversity in Active Ulcerative Colitis

(2017) Vinita Jacob et al.   INFLAMMATORY BOWEL DISEASES

Muscadine Grape (Vitis rotundifolia) or Wine Phytochemicals Reduce Intestinal Inflammation in Mice with Dextran Sulfate Sodium-Induced Colitis

(2017) Ruiqi Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Novel therapeutic targets for inflammatory bowel disease

(2017) Marjorie Argollo et al.   JOURNAL OF AUTOIMMUNITY

Faecal Microbiota Transplantation for Inflammatory Bowel Disease: A Systematic Review and Meta-analysis

(2017) Sudarshan Paramsothy et al.   Journal of Crohns & Colitis

Multidonor intensive faecal microbiota transplantation for active ulcerative colitis: a randomised placebo-controlled trial

(2017) Sudarshan Paramsothy et al.   LANCET

Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study

(2017) Subra Kugathasan et al.   LANCET

Analysis of murine and human Treg subsets in inflammatory bowel disease

(2017) Xiaoyun Sun et al.   Molecular Medicine Reports

Microbiota-activated PPAR-γ signaling inhibits dysbiotic Enterobacteriaceae expansion

(2017) Mariana X. Byndloss et al.   SCIENCE

Effects of Probiotics, Prebiotics, and Synbiotics on Human Health

(2017) et al.   Nutrients

Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota

(2017) Chen Diling et al.   Oncotarget

Lactobacillus fermentum IM12 attenuates inflammation in mice by inhibiting NF-κB-STAT3 signalling pathway

(2017) S.-M. Lim et al.   Beneficial Microbes

In Silico Screening of the Human Gut Metaproteome Identifies Th17-Promoting Peptides Encrypted in Proteins of Commensal Bacteria

(2017) Claudio Hidalgo-Cantabrana et al.   Frontiers in Microbiology

Next-generation probiotics: the spectrum from probiotics to live biotherapeutics

(2017) Paul W. O’Toole et al.   Nature Microbiology

An orally administered butyrate-releasing derivative reduces neutrophil recruitment and inflammation in dextran sulphate sodium-induced murine colitis

(2016) Raffaele Simeoli et al.   BRITISH JOURNAL OF PHARMACOLOGY

Reduced Abundance of Butyrate-Producing Bacteria Species in the Fecal Microbial Community in Crohn's Disease

(2016) Kenichiro Takahashi et al.   DIGESTION

Neonatal colonization of mice with LGG promotes intestinal development and decreases susceptibility to colitis in adulthood

(2016) F Yan et al.   Mucosal Immunology

The role of neutrophils and NETosis in autoimmune and renal diseases

(2016) Sarthak Gupta et al.   Nature Reviews Nephrology

Role and mechanisms of action ofEscherichia coliNissle 1917 in the maintenance of remission in ulcerative colitis patients: An update

(2016) Franco Scaldaferri et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Role of regulatory T cell in the pathogenesis of inflammatory bowel disease

(2016) Akiko Yamada et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Role of antibiotics for treatment of inflammatory bowel disease

(2016) Orna Nitzan   WORLD JOURNAL OF GASTROENTEROLOGY

Doxycycline, metronidazole and isotretinoin: Do they modify microRNA/mRNA expression profiles and function in murine T-cells?

(2016) Eugenia Becker et al.   Scientific Reports

Review article: the potential mechanisms of action of rifaximin in the management of inflammatory bowel diseases

(2015) R. B. Sartor   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Efficacy of probiotic treatment withBifidobacterium longum 536for induction of remission in active ulcerative colitis: A randomized, double-blinded, placebo-controlled multicenter trial

(2015) Hiroyuki Tamaki et al.   Digestive Endoscopy

Preventive rather than therapeutic treatment with high fiber diet attenuates clinical and inflammatory markers of acute and chronic DSS-induced colitis in mice

(2015) Ana Letícia Malheiros Silveira et al.   EUROPEAN JOURNAL OF NUTRITION

Fecal Microbiota Transplantation Induces Remission in Patients With Active Ulcerative Colitis in a Randomized Controlled Trial

(2015) Paul Moayyedi et al.   GASTROENTEROLOGY

Findings From a Randomized Controlled Trial of Fecal Transplantation for Patients With Ulcerative Colitis

(2015) Noortje G. Rossen et al.   GASTROENTEROLOGY

Probiotics, prebiotics and synbiotics- a review

(2015) Kavita. R. Pandey et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Role of epithelial cells in the pathogenesis and treatment of inflammatory bowel disease

(2015) Ryuichi Okamoto et al.   JOURNAL OF GASTROENTEROLOGY

The Probiotic Mixture VSL#3 Has Differential Effects on Intestinal Immune Parameters in Healthy Female BALB/c and C57BL/6 Mice

(2015) Rob Mariman et al.   JOURNAL OF NUTRITION

Sphingolipids from a Symbiotic Microbe Regulate Homeostasis of Host Intestinal Natural Killer T Cells

(2014) Dingding An et al.   CELL

IBD Candidate Genes and Intestinal Barrier Regulation

(2014) Declan F. McCole   INFLAMMATORY BOWEL DISEASES

Protective mucosal immunity mediated by epithelial CD1d and IL-10

(2014) Torsten Olszak et al.   NATURE

Focused specificity of intestinal TH17 cells towards commensal bacterial antigens

(2014) Yi Yang et al.   NATURE

Myosin Light Chain Kinase Expression Induced via Tumor Necrosis Factor Receptor 2 Signaling in the Epithelial Cells Regulates the Development of Colitis-Associated Carcinogenesis

(2014) Masahiro Suzuki et al.   PLoS One

Fluctuations in butyrate-producing bacteria in ulcerative colitis patients of North India

(2013) Reena Kumari   WORLD JOURNAL OF GASTROENTEROLOGY

Gut Microbial Flora, Prebiotics, and Probiotics in IBD: Their Current Usage and Utility

(2013) Franco Scaldaferri et al.   Biomed Research International

In vitrofermentation of grape seed flavan-3-ol fractions by human faecal microbiota: changes in microbial groups and phenolic metabolites

(2012) Carolina Cueva et al.   FEMS MICROBIOLOGY ECOLOGY

Probiotic and postbiotic activity in health and disease: comparison on a novel polarised ex-vivo organ culture model

(2012) Katerina Tsilingiri et al.   GUT

Inflammatory bowel disease: an impaired barrier disease

(2012) Simon Jäger et al.   LANGENBECKS ARCHIVES OF SURGERY

IL-9-producing invariant NKT cells protect against DSS-induced colitis in an IL-4-dependent manner

(2012) H S Kim et al.   Mucosal Immunology

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Postbiotics: what else?

(2012) K. Tsilingiri et al.   Beneficial Microbes

Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism

(2011) Fang Yan et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-23–responsive innate lymphoid cells are increased in inflammatory bowel disease

(2011) Alessandra Geremia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Selective C-Rel Activation via Malt1 Controls Anti-Fungal TH-17 Immunity by Dectin-1 and Dectin-2

(2011) Sonja I. Gringhuis et al.   PLoS Pathogens

Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine

(2010) Ken Cadwell et al.   CELL

Crohn's Disease Susceptibility Gene Interactions, a NOD to the Newcomer ATG16L1

(2010) Ken Cadwell   GASTROENTEROLOGY

CD4+ Lymphoid Tissue-Inducer Cells Promote Innate Immunity in the Gut

(2010) Gregory F. Sonnenberg et al.   IMMUNITY

Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohnʼs disease

(2010) S. C. Ng et al.   INFLAMMATORY BOWEL DISEASES

The intestinal anti-inflammatory effect of minocycline in experimental colitis involves both its immunomodulatory and antimicrobial properties

(2010) Natividad Garrido-Mesa et al.   PHARMACOLOGICAL RESEARCH

Induction of Colonic Regulatory T Cells by Indigenous Clostridium Species

(2010) K. Atarashi et al.   SCIENCE

Interleukin-21 triggers effector cell responses in the gut

(2010) Daniela De Nitto   WORLD JOURNAL OF GASTROENTEROLOGY

A common role for Atg16L1, Atg5, and Atg7 in small intestinal Paneth cells and Crohn disease

(2009) Ken Cadwell et al.   Autophagy

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

Upregulation of T-bet and tight junction molecules by Bifidobactrium longum improves colonic inflammation of ulcerative colitis

(2009) Yasuhiro Takeda et al.   INFLAMMATORY BOWEL DISEASES

16S rRNA gene sequence-based analysis of clostridia related to conversion of germfree mice to the normal state

(2009) Y. Momose et al.   JOURNAL OF APPLIED MICROBIOLOGY

Orally administered L. lactis secreting an anti-TNF Nanobody demonstrate efficacy in chronic colitis

(2009) K Vandenbroucke et al.   Mucosal Immunology

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Comparison of the Immunomodulatory Properties of Three Probiotic Strains of Lactobacilli Using Complex Culture Systems: Prediction for In Vivo Efficacy

(2009) Erika Mileti et al.   PLoS One

Importance of nutrition in inflammatory bowel disease

(2009) Alfredo José Lucendo et al.   WORLD JOURNAL OF GASTROENTEROLOGY