The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling

Insulin signaling in health and disease

(2021) Alan R. Saltiel   JOURNAL OF CLINICAL INVESTIGATION

Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration

(2021) Henry Querfurth et al.   Molecular Neurodegeneration

Nuclear dynamics and stress responses in Alzheimer’s disease

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Insulin signaling pathway and related molecules: Role in neurodegeneration and Alzheimer's disease

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Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex

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Brain insulin resistance in Alzheimer's disease and related disorders: mechanisms and therapeutic approaches

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Molecular and cellular mechanisms underlying the pathogenesis of Alzheimer’s disease

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Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior

(2019) Marion Soto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroinflammation and fractalkine signaling in Alzheimer’s disease

(2019) Dylan J. Finneran et al.   Journal of Neuroinflammation

Insulin Signaling Impairment in the Brain as a Risk Factor in Alzheimer’s Disease

(2019) Christian Hölscher   Frontiers in Aging Neuroscience

Insulin and Autophagy in Neurodegeneration

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The intracellular domain of CX3CL1 regulates adult neurogenesis and Alzheimer’s amyloid pathology

(2019) Qingyuan Fan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Brain Insulin Resistance and Hippocampal Plasticity: Mechanisms and Biomarkers of Cognitive Decline

(2019) Matteo Spinelli et al.   Frontiers in Neuroscience

CX3CL1 intracellular domain and adult neurogenesis

(2019) Marc R. Benoit et al.   Aging-US

Activated CX3CL1/Smad2 Signals Prevent Neuronal Loss and Alzheimer's Tau Pathology-Mediated Cognitive Dysfunction

(2019) Qingyuan Fan et al.   JOURNAL OF NEUROSCIENCE

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

(2018) Steven E. Arnold et al.   Nature Reviews Neurology

Neuronal Cell Death

(2018) Michael Fricker et al.   PHYSIOLOGICAL REVIEWS

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(2018) Hongjun Fu et al.   NATURE NEUROSCIENCE

Neuronal survival in the brain: neuron type-specific mechanisms

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Insulin Resistance and Neurodegeneration: Progress Towards the Development of New Therapeutics for Alzheimer’s Disease

(2016) Suzanne M. de la Monte   DRUGS

Control of adult neurogenesis by programmed cell death in the mammalian brain

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IGF-I: A Key Growth Factor that Regulates Neurogenesis and Synaptogenesis from Embryonic to Adult Stages of the Brain

(2016) Vanesa Nieto-Estévez et al.   Frontiers in Neuroscience

Active FOXO1 Is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming

(2015) C. H. Diep et al.   MOLECULAR CANCER RESEARCH

SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis

(2015) Alejandro Amador-Arjona et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FOXO transcription factors: key regulators of cellular quality control

(2014) Ashley E. Webb et al.   TRENDS IN BIOCHEMICAL SCIENCES

Modulating neurotoxicity through CX3CL1/CX3CR1 signaling

(2014) Cristina Limatola et al.   Frontiers in Cellular Neuroscience

Targeting AKT with the allosteric AKT inhibitor MK-2206 in non-small cell lung cancer cells with acquired resistance to cetuximab

(2013) Mari Iida et al.   CANCER BIOLOGY & THERAPY

FOXOs: signalling integrators for homeostasis maintenance

(2013) Astrid Eijkelenboom et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nonautonomous Regulation of Neuronal Migration by Insulin Signaling, DAF-16/FOXO, and PAK-1

(2013) Lisa M. Kennedy et al.   Cell Reports

FoxOs in neural stem cell fate decision

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The Complex Biology of FOXO

(2011) Maria Monsalve et al.   CURRENT DRUG TARGETS

FOXO1: A Potential Target for Human Diseases

(2011) Huarui Lu et al.   CURRENT DRUG TARGETS

Anticholinergics boost the pathological process of neurodegeneration with increased inflammation in a tauopathy mouse model

(2011) Yasumasa Yoshiyama et al.   NEUROBIOLOGY OF DISEASE

The Molecular Assembly of Amyloid Aβ Controls Its Neurotoxicity and Binding to Cellular Proteins

(2011) Claudia Manzoni et al.   PLoS One

Nutrition-Responsive Glia Control Exit of Neural Stem Cells from Quiescence

(2010) James M. Chell et al.   CELL

Understanding FOXO, New Views on Old Transcription Factors

(2010) F. Zanella et al.   CURRENT CANCER DRUG TARGETS

SOX5 controls cell cycle progression in neural progenitors by interfering with the WNT–β-catenin pathway

(2010) Patricia L Martinez-Morales et al.   EMBO REPORTS

BH3-only proteins BIM and PUMA in the regulation of survival and neuronal differentiation of newly generated cells in the adult mouse hippocampus

(2010) E C Bunk et al.   Cell Death & Disease

FoxOs Cooperatively Regulate Diverse Pathways Governing Neural Stem Cell Homeostasis

(2009) Ji-hye Paik et al.   Cell Stem Cell

FOXO Transcription Factors Enforce Cell Cycle Checkpoints and Promote Survival of Hematopoietic Cells after DNA Damage

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Age-dependent FOXO regulation of p27Kip1 expression via a conserved binding motif in rat muscle precursor cells

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