Aluminum activates NLRP3 inflammasome-mediated pyroptosis via reactive oxygen species to induce liver injury in mice
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Aluminum activates NLRP3 inflammasome-mediated pyroptosis via reactive oxygen species to induce liver injury in mice
Authors
Keywords
-
Journal
CHEMICO-BIOLOGICAL INTERACTIONS
Volume -, Issue -, Pages 110229
Publisher
Elsevier BV
Online
2022-10-27
DOI
10.1016/j.cbi.2022.110229
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- ROS antagonizes the protection of Parkin-mediated mitophagy against aluminum-induced liver inflammatory injury in mice
- (2022) Bonan Xiao et al. FOOD AND CHEMICAL TOXICOLOGY
- Cigarette smoke extract induces pyroptosis in human bronchial epithelial cells through the ROS/NLRP3/caspase-1 pathway
- (2021) Meng-Yu Zhang et al. LIFE SCIENCES
- Necroptosis, pyroptosis and apoptosis: an intricate game of cell death
- (2021) Damien Bertheloot et al. Cellular & Molecular Immunology
- Aluminum environmental pollution: the silent killer
- (2021) Reema H. Alasfar et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- ROS-mediated mitophagy and apoptosis are involved in aluminum-induced femoral impairment in mice
- (2021) Yilong Cui et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Aluminum impairs cognitive function by activating DDX3X-NLRP3-mediated pyroptosis signaling pathway
- (2021) Wudi Hao et al. FOOD AND CHEMICAL TOXICOLOGY
- Parkin-mediated mitochondrial quality control protects against aluminum-induced liver damage in mice
- (2021) Bonan Xiao et al. FOOD AND CHEMICAL TOXICOLOGY
- Blockade of the NLRP3/caspase-1 axis attenuates ketamine-induced hippocampus pyroptosis and cognitive impairment in neonatal rats
- (2021) Zhiheng Zhang et al. Journal of Neuroinflammation
- Reactive oxygen species trigger NF-κB-mediated NLRP3 inflammasome activation involvement in low-dose CdTe QDs exposure-induced hepatotoxicity
- (2021) Yanting Pang et al. Redox Biology
- Aluminum and aluminum oxide nanomaterials uptake after oral exposure - a comparative study
- (2020) Benjamin C. Krause et al. Scientific Reports
- Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer
- (2020) Jin-Feng Teng et al. Cancers
- Critical role of estrogen in the progression of chronic liver diseases
- (2020) Devaraj Ezhilarasan Hepatobiliary & Pancreatic Diseases International
- Natural Compounds Rosmarinic Acid and Carvacrol Counteract Aluminium-Induced Oxidative Stress
- (2020) Juste Baranauskaite et al. MOLECULES
- Lycorine ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3 inflammasome activation and pyroptosis
- (2020) Qing Liang et al. PHARMACOLOGICAL RESEARCH
- Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis
- (2020) Susanne Gaul et al. JOURNAL OF HEPATOLOGY
- Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling
- (2020) Yuqing Lin et al. Frontiers in Immunology
- Aluminum induced oxidative stress, astrogliosis and cell death in rat astrocytes, is prevented by curcumin
- (2020) Wafaa Laabbar et al. JOURNAL OF CHEMICAL NEUROANATOMY
- Lipopolysaccharide (LPS) Aggravates High Glucose- and Hypoxia/Reoxygenation-Induced Injury through Activating ROS-Dependent NLRP3 Inflammasome-Mediated Pyroptosis in H9C2 Cardiomyocytes
- (2019) Zhen Qiu et al. Journal of Diabetes Research
- Multifactorial functions of the inflammasome component NLRP3 in pathogenesis of chronic kidney diseases
- (2019) Shrikant R. Mulay KIDNEY INTERNATIONAL
- MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition
- (2019) Rebecca C. Coll et al. Nature Chemical Biology
- Long-term accumulation of metals in the skeleton as related to osteoporotic derangements
- (2019) Geir Bjorklund et al. CURRENT MEDICINAL CHEMISTRY
- The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
- (2019) Nathan Kelley et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Taurine alleviates schistosoma-induced liver injury by inhibiting TXNIP/NLRP3 inflammasome signal pathway and pyroptosis
- (2019) Xin Liu et al. INFECTION AND IMMUNITY
- A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation
- (2019) CongXiao Zhang et al. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy
- Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice
- (2018) Bing Xu et al. JOURNAL OF HEPATOLOGY
- Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis
- (2018) Xianxian Wu et al. Cell Death & Disease
- Pyroptosis versus necroptosis: similarities, differences, and crosstalk
- (2018) Daniel Frank et al. CELL DEATH AND DIFFERENTIATION
- Nicotinamide mononucleotide alleviates Aluminum induced bone loss by inhibiting the TXNIP-NLRP3 inflammasome
- (2018) Haipeng Liang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Interleukin-10 secreted by mesenchymal stem cells attenuates acute liver failure through inhibiting pyroptosis
- (2017) Jinglin Wang et al. HEPATOLOGY RESEARCH
- Aluminum chloride caused liver dysfunction and mitochondrial energy metabolism disorder in rat
- (2017) Feibo Xu et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
- (2017) Jianjin Shi et al. TRENDS IN BIOCHEMICAL SCIENCES
- Gasdermins: Effectors of Pyroptosis
- (2017) Stephen B. Kovacs et al. TRENDS IN CELL BIOLOGY
- Metal Ion Imbalance-Related Oxidative Stress Is Involved in the Mechanisms of Liver Injury in a Rat Model of Chronic Aluminum Exposure
- (2016) Yang Yang et al. BIOLOGICAL TRACE ELEMENT RESEARCH
- Proposal for management and alkalinity transformation of bauxite residue in China
- (2016) Shengguo Xue et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Aluminum trichloride induces bone impairment through TGF-β1/Smad signaling pathway
- (2016) Xudong Sun et al. TOXICOLOGY
- Understanding Aspects of Aluminum Exposure in Alzheimer's Disease Development
- (2015) Ramesh Kandimalla et al. BRAIN PATHOLOGY
- Pyroptotic cell death defends against intracellular pathogens
- (2015) Ine Jorgensen et al. IMMUNOLOGICAL REVIEWS
- Initiation and perpetuation of NLRP3 inflammasome activation and assembly
- (2015) Eric I. Elliott et al. IMMUNOLOGICAL REVIEWS
- Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
- (2015) Jianjin Shi et al. NATURE
- How aluminum, an intracellular ROS generator promotes hepatic and neurological diseases: the metabolic tale
- (2013) Sungwon Han et al. CELL BIOLOGY AND TOXICOLOGY
- Hepatic response to aluminum toxicity: Dyslipidemia and liver diseases
- (2011) Ryan J. Mailloux et al. EXPERIMENTAL CELL RESEARCH
- Caspase-1-induced pyroptotic cell death
- (2011) Edward A. Miao et al. IMMUNOLOGICAL REVIEWS
- Updated aluminum pharmacokinetics following infant exposures through diet and vaccination
- (2011) Robert J. Mitkus et al. VACCINE
- The NLRP3 Inflammasome: A Sensor for Metabolic Danger?
- (2010) K. Schroder et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started