ROS antagonizes the protection of Parkin-mediated mitophagy against aluminum-induced liver inflammatory injury in mice

Upregulation of brain cholesterol levels inhibits mitophagy in Alzheimer disease

(2021) Vicente Roca-Agujetas et al.   Autophagy

PINK1‐mediated mitophagy maintains pluripotency through optineurin

(2021) Chaoqun Wang et al.   CELL PROLIFERATION

Mitophagy and apoptosis mediated by ROS participate in AlCl3-induced MC3T3-E1 cell dysfunction

(2021) Menglin Liu et al.   FOOD AND CHEMICAL TOXICOLOGY

Assessment of the in vivo genotoxicity of pendimethalin via mitochondrial bioenergetics and transcriptional profiles during embryogenesis in zebrafish: Implication of electron transport chain activity and developmental defects

(2021) Hahyun Park et al.   JOURNAL OF HAZARDOUS MATERIALS

Calcitriol Alleviates Hyperosmotic Stress-Induced Corneal Epithelial Cell Damage via Inhibiting the NLRP3–ASC–Caspase-1–GSDMD Pyroptosis Pathway in Dry Eye Disease

(2021) Jing Zhang et al.   Journal of Inflammation Research

ROS-mediated mitophagy and apoptosis are involved in aluminum-induced femoral impairment in mice

(2021) Yilong Cui et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Parkin-mediated mitochondrial quality control protects against aluminum-induced liver damage in mice

(2021) Bonan Xiao et al.   FOOD AND CHEMICAL TOXICOLOGY

Cadmium induces mitophagy via AMP‐activated protein kinases activation in a PINK1/Parkin‐dependent manner in PC12 cells

(2020) Tao Wang et al.   CELL PROLIFERATION

Imiquimod-induced ROS production disrupts the balance of mitochondrial dynamics and increases mitophagy in skin cancer cells

(2020) Kai-Cheng Chuang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Mitophagy regulates integrity of mitochondria at synapses and is critical for synaptic maintenance

(2020) Sinsuk Han et al.   EMBO REPORTS

Bavachin suppresses human placental choriocarcinoma cells by targeting electron transport chain complexes and mitochondrial dysfunction

(2020) Jin-Young Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Biodegradable hollow mesoporous organosilica nanotheranostics (HMON) for multi-mode imaging and mild photo-therapeutic-induced mitochondrial damage on gastric cancer

(2020) Weihong Guo et al.   JOURNAL OF NANOBIOTECHNOLOGY

Parkin Overexpression Alleviates Cardiac Aging through Facilitating K63-Polyubiquitination of TBK1 to Facilitate Mitophagy

(2020) Beilei Gao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Protective Effects of Melatonin on Aluminum-Induced Hepatotoxicity and Nephrotoxicity in Rats

(2020) Mohamed S. Othman et al.   Oxidative Medicine and Cellular Longevity

ROS-mediated NLRP3 inflammasome activation participates in the response against Neospora caninum infection

(2020) Lu Li et al.   Parasites & Vectors

Glutathionylated and Fe–S cluster containing hMIA40 (CHCHD4) regulates ROS and mitochondrial complex III and IV activities of the electron transport chain

(2020) Venkata Ramana Thiriveedi et al.   Redox Biology

Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy

(2019) Tao Zhou et al.   Redox Biology

Impaired mitophagy triggers NLRP3 inflammasome activation during the progression from nonalcoholic fatty liver to nonalcoholic steatohepatitis

(2019) Ning-Ping Zhang et al.   LABORATORY INVESTIGATION

Inflammatory cytokines associated with cancer growth induce mitochondria and cytoskeleton alterations in cardiomyocytes

(2019) Maria Buoncervello et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice

(2019) Hua Wang et al.   Redox Biology

PHB2 (prohibitin 2) promotes PINK1-PRKN/Parkin-dependent mitophagy by the PARL-PGAM5-PINK1 axis

(2019) Chaojun Yan et al.   Autophagy

IRGM restrains NLRP3 inflammasome activation by mediating its SQSTM1/p62-dependent selective autophagy

(2019) Subhash Mehto et al.   Autophagy

ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism

(2019) Rendong Fang et al.   Mucosal Immunology

Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome

(2019) Lingbin Sun et al.   Cell Death & Disease

PINK1-parkin pathway of mitophagy protects against contrast-induced acute kidney injury via decreasing mitochondrial ROS and NLRP3 inflammasome activation

(2019) Qisheng Lin et al.   Redox Biology

Mitophagy protects against acetaminophen-induced acute liver injury in mice through inhibiting NLRP3 inflammasome activation

(2019) Shulin Shan et al.   BIOCHEMICAL PHARMACOLOGY

The ADP/ATP translocase drives mitophagy independent of nucleotide exchange

(2019) Atsushi Hoshino et al.   NATURE

Aflatoxin B1 promotes autophagy associated with oxidative stress-related PI3K/AKT/mTOR signaling pathway in mice testis

(2019) Wanyue Huang et al.   ENVIRONMENTAL POLLUTION

Curcumin ameliorates oxidative stress-induced intestinal barrier injury and mitochondrial damage by promoting Parkin dependent mitophagy through AMPK-TFEB signal pathway

(2019) Shuting Cao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Molybdenum and cadmium co-induce oxidative stress and apoptosis through mitochondria-mediated pathway in duck renal tubular epithelial cells

(2019) Chang Wang et al.   JOURNAL OF HAZARDOUS MATERIALS

Parkin and Nrf2 prevent oxidative stress-induced apoptosis in intervertebral endplate chondrocytes via inducing mitophagy and anti-oxidant defenses

(2019) Liang Kang et al.   LIFE SCIENCES

N-Acetylcysteine Reduces ROS-Mediated Oxidative DNA Damage and PI3K/Akt Pathway Activation Induced by Helicobacter pylori Infection

(2018) Chuan Xie et al.   Oxidative Medicine and Cellular Longevity

FUNDC1-mediated mitophagy suppresses hepatocarcinogenesis by inhibition of inflammasome activation

(2018) Wenhui Li et al.   HEPATOLOGY

Nickel sulfate induced apoptosis via activating ROS-dependent mitochondria and endoplasmic reticulum stress pathways in rat Leydig cells

(2017) Lingyue Zou et al.   ENVIRONMENTAL TOXICOLOGY

Association of chitosan and aluminium as a new adjuvant strategy for improved vaccination

(2017) F. Lebre et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Aluminum chloride caused liver dysfunction and mitochondrial energy metabolism disorder in rat

(2017) Feibo Xu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mitochondrial Quality Control and Disease: Insights into Ischemia-Reperfusion Injury

(2017) Anthony R. Anzell et al.   MOLECULAR NEUROBIOLOGY

Inhibition of osteoblast differentiation by aluminum trichloride exposure is associated with inhibition of BMP-2/Smad pathway component expression

(2016) Xu Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy

(2016) Thanh N. Nguyen et al.   TRENDS IN CELL BIOLOGY

Disruption of erythrocyte antioxidant defense system, hematological parameters, induction of pro-inflammatory cytokines and DNA damage in liver of co-exposed rats to aluminium and acrylamide

(2015) Imen Ghorbel et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications

(2015) Thomas M. Durcan et al.   GENES & DEVELOPMENT

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

(2015) Michael Lazarou et al.   NATURE

Cadmium induces mitophagy through ROS-mediated PINK1/Parkin pathway

(2014) Xue Wei et al.   TOXICOLOGY MECHANISMS AND METHODS

Aluminium in allergen-specific subcutaneous immunotherapy – A German perspective

(2014) Matthias F. Kramer et al.   VACCINE

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

(2010) Seok Min Jin et al.   JOURNAL OF CELL BIOLOGY

Aluminium neurotoxicity: neurobehavioural and oxidative aspects

(2009) Vijay Kumar et al.   ARCHIVES OF TOXICOLOGY

Effects of oral aluminum exposure on behavior and neurogenesis in a transgenic mouse model of Alzheimer's disease

(2008) D. Ribes et al.   EXPERIMENTAL NEUROLOGY