Gallic Acid Alleviates Gouty Arthritis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Through Enhancing Nrf2 Signaling

Gallic acid protects against the COPD-linked lung inflammation and emphysema in mice

(2020) Esha Singla et al.   INFLAMMATION RESEARCH

Wedelolactone facilitates Ser/Thr phosphorylation of NLRP3 dependent on PKA signalling to block inflammasome activation and pyroptosis

(2020) Hao Pan et al.   CELL PROLIFERATION

Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis

(2019) Ping Wang et al.   Nature Communications

Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome

(2019) Humayun Sharif et al.   NATURE

Gallic Acid Attenuated LPS-Induced Neuroinflammation: Protein Aggregation and Necroptosis

(2019) Yu-Ling Liu et al.   MOLECULAR NEUROBIOLOGY

Tranilast directly targets NLRP3 to treat inflammasome‐driven diseases

(2018) Yi Huang et al.   EMBO Molecular Medicine

The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages

(2018) Charles L. Evavold et al.   IMMUNITY

Curcumin Suppresses IL-1β Secretion and Prevents Inflammation through Inhibition of the NLRP3 Inflammasome

(2018) Haipeng Yin et al.   JOURNAL OF IMMUNOLOGY

Probing Gallic Acid for Its Broad Spectrum Applications

(2018) Sneha Choubey et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

(2018) Masayuki Yamamoto et al.   PHYSIOLOGICAL REVIEWS

Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity

(2018) Hongbin He et al.   Nature Communications

Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis

(2018) Yachun Han et al.   Redox Biology

In vivo and in vitro evidence for the involvement of Nrf2-antioxidant response element signaling pathway in the inflammation and oxidative stress induced by particulate matter (PM10): the effective role of gallic acid

(2018) Maryam Radan et al.   FREE RADICAL RESEARCH

PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation

(2018) Jueqi Chen et al.   NATURE

Terminalia bellirica (Gaertn.) Roxb. Extract and Gallic Acid Attenuate LPS-Induced Inflammation and Oxidative Stress via MAPK/NF-κB and Akt/AMPK/Nrf2 Pathways

(2018) Miori Tanaka et al.   Oxidative Medicine and Cellular Longevity

Inflammation and Oxidative Stress in an Obese State and the Protective Effects of Gallic Acid

(2018) Phiwayinkosi Dludla et al.   Nutrients

Gallic acid improved inflammation via NF-κB pathway in TNBS-induced ulcerative colitis

(2018) Lei Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Gallic Acid and Gallates in Human Health and Disease: Do Mitochondria Hold the Key to Success?

(2017) Rekha Yamini Kosuru et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inflammation in gout: mechanisms and therapeutic targets

(2017) Alexander K. So et al.   Nature Reviews Rheumatology

Epigallocatechin gallate inhibits urate crystals-induced peritoneal inflammation in C57BL/6 mice

(2016) Jhih-Jia Jhang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

Sulforaphane Protects Pancreatic Acinar Cell Injury by Modulating Nrf2-Mediated Oxidative Stress and NLRP3 Inflammatory Pathway

(2016) Zhaojun Dong et al.   Oxidative Medicine and Cellular Longevity

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

(2015) Wan-ting He et al.   CELL RESEARCH

NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component

(2015) Hexin Shi et al.   NATURE IMMUNOLOGY

Piperine metabolically regulates peritoneal resident macrophages to potentiate their functions against bacterial infection

(2015) Hao Pan et al.   Oncotarget

Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

(2015) Joe Dan Dunn et al.   Redox Biology

The Second-Generation mTOR Kinase Inhibitor INK128 Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated RAW 264.7 Cells

(2014) Hao Pan et al.   INFLAMMATION

Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation

(2014) Hiroe Honda et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Alkyl esters of gallic acid as anticancer agents: A review

(2012) Claudriana Locatelli et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Toona sinensis and its major bioactive compound gallic acid inhibit LPS-induced inflammation in nuclear factor-κB transgenic mice as evaluated by in vivo bioluminescence imaging

(2012) Chien-Yun Hsiang et al.   FOOD CHEMISTRY

Basic Calcium Phosphate Crystals Induce Monocyte/Macrophage IL-1  Secretion through the NLRP3 Inflammasome In Vitro

(2011) B. Pazar et al.   JOURNAL OF IMMUNOLOGY