Cigarette smoke extract induces pyroptosis in human bronchial epithelial cells through the ROS/NLRP3/caspase-1 pathway

Ghrelin alleviates traumatic brain injury-induced acute lung injury through pyroptosis/NF-κB pathway

(2020) Xue-Fei Shao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cigarette smoke induces the pyroptosis of urothelial cells through ROS/NLRP3/caspase‐1 signaling pathway

(2020) Zonglong Wu et al.   NEUROUROLOGY AND URODYNAMICS

Cigarette smoke downregulates Nur77 to exacerbate inflammation in chronic obstructive pulmonary disease (COPD)

(2020) Aravind T. Reddy et al.   PLoS One

Air pollution: how many cigarettes does each Pole ‘smoke’ every year and how does it influence health, with special respect to lung cancer?

(2019) Robert Chudzik et al.   ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE

Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis

(2019) Masahiro Yoshida et al.   Nature Communications

Effect of Iron Deficiency on a Murine Model of Smoke-Induced Emphysema

(2019) Kento Sato et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Melatonin alleviates cigarette smoke-induced endothelial cell pyroptosis through inhibiting ROS/NLRP3 axis

(2019) Xuebin Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Trichostatin A inhibits skeletal muscle atrophy induced by cigarette smoke exposure in mice

(2019) Jingjing Ding et al.   LIFE SCIENCES

The role of cigarette smoke-induced epigenetic alterations in inflammation

(2019) Dandan Zong et al.   Epigenetics & Chromatin

Amurensin H, a Derivative From Resveratrol, Ameliorates Lipopolysaccharide/Cigarette Smoke–Induced Airway Inflammation by Blocking the Syk/NF-κB Pathway

(2019) Yannan Fan et al.   Frontiers in Pharmacology

Long non-coding RNA MEG3 regulates CSE-induced apoptosis and inflammation via regulating miR-218 in 16HBE cells

(2019) Beibei Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatotoxic effects of inhalation exposure to polycyclic aromatic hydrocarbons on lipid metabolism of C57BL/6 mice

(2019) Fang Li et al.   ENVIRONMENT INTERNATIONAL

Cigarette smoke inhibits the NLRP3 inflammasome and leads to caspase‐1 activation via the TLR4‐TRIF‐caspase‐8 axis in human macrophages

(2019) Marco Buscetta et al.   FASEB JOURNAL

Mice overexpressing latent matrix metalloproteinase-2 develop lung emphysema after short-term exposure to cigarette smoke extract

(2018) Masahiro Onishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autoinflammatory disease in the lung

(2018) Thomas Scambler et al.   IMMUNOLOGY

Curcumin Attenuates Airway Inflammation and Airway Remolding by Inhibiting NF-κB Signaling and COX-2 in Cigarette Smoke-Induced COPD Mice

(2018) Jin Yuan et al.   INFLAMMATION

A large lung gene expression study identifying IL1B as a novel player in airway inflammation in COPD airway epithelial cells

(2018) Gao Yi et al.   INFLAMMATION RESEARCH

NLRP3/ASC-mediated alveolar macrophage pyroptosis enhances HMGB1 secretion in acute lung injury induced by cardiopulmonary bypass

(2018) Lei Hou et al.   LABORATORY INVESTIGATION

Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study

(2018) Chen Wang et al.   LANCET

Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis

(2018) Xianxian Wu et al.   Cell Death & Disease

Nicotine induces endothelial dysfunction and promotes atherosclerosis via GTPCH1

(2018) Jingyuan Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cytotoxic effects of heated tobacco products (HTP) on human bronchial epithelial cells

(2018) Noel J Leigh et al.   TOBACCO CONTROL

COPD Guidelines: A Review of the 2018 GOLD Report

(2018) Shireen Mirza et al.   MAYO CLINIC PROCEEDINGS

Interleukin-35 expression protects against cigarette smoke-induced lung inflammation in mice

(2018) Xiuhe Pan et al.   BIOMEDICINE & PHARMACOTHERAPY

MicroRNA-150 protects against cigarette smoke-induced lung inflammation and airway epithelial cell apoptosis through repressing p53: MicroRNA-150 in CS-induced lung inflammation

(2017) H Xue et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Cigarette smoke alters the secretome of lung epithelial cells

(2017) Alessandra Mossina et al.   PROTEOMICS

Activating transcription factor 3 represses cigarette smoke-induced IL6 and IL8 expression via suppressing NF-κB activation

(2017) Yan-ping Wu et al.   TOXICOLOGY LETTERS

Role of the inflammasome in chronic obstructive pulmonary disease (COPD)

(2017) Chiara Colarusso et al.   Oncotarget

Comparison and evaluation of two different methods to establish the cigarette smoke exposure mouse model of COPD

(2017) Jiaze Shu et al.   Scientific Reports

The Nucleotide-Binding Oligomerization Domain–Like Receptor Family Pyrin Domain-Containing 3 Inflammasome Regulates Bronchial Epithelial Cell Injury and Proapoptosis after Exposure to Biomass Fuel Smoke

(2016) Chen Li et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pyroptosis

(2016) Lieselotte Vande Walle et al.   CURRENT BIOLOGY

Therapeutic Effects of Resveratrol in a Mouse Model of LPS and Cigarette Smoke-Induced COPD

(2016) Jinlong Chen et al.   INFLAMMATION

Oroxylin A attenuates cigarette smoke-induced lung inflammation by activating Nrf2

(2016) Jihe Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A standardized bark extract of Pinus pinaster Aiton (Pycnogenol®) attenuated chronic obstructive pulmonary disease via Erk-sp1 signaling pathway

(2016) Na-Rae Shin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Atrial natriuretic peptide down-regulates LPS/ATP-mediated IL-1β release by inhibiting NF-kB, NLRP3 inflammasome and caspase-1 activation in THP-1 cells

(2015) Letizia Mezzasoma et al.   IMMUNOLOGIC RESEARCH

Suppression of NLRX1 in chronic obstructive pulmonary disease

(2015) Min-Jong Kang et al.   JOURNAL OF CLINICAL INVESTIGATION

Status of Cardiovascular Health in Chinese Adults

(2015) Yufang Bi et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Smoking and Cardiovascular Disease

(2014) Barbara Messner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Caspase-1: is IL-1 just the tip of the ICEberg?

(2012) A Denes et al.   Cell Death & Disease

Caspase-1-induced pyroptotic cell death

(2011) Edward A. Miao et al.   IMMUNOLOGICAL REVIEWS

Inflammasome-dependent Pyroptosis and IL-18 Protect against Burkholderia pseudomallei Lung Infection while IL-1β Is Deleterious

(2011) Ivonne Ceballos-Olvera et al.   PLoS Pathogens

The Inflammasomes

(2010) Kate Schroder et al.   CELL

NOD-like subfamily of the nucleotide-binding domain and leucine-rich repeat containing family receptors and their expression in channel catfish

(2009) Zhenxia Sha et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice

(2009) Koustav Ganguly et al.   Particle and Fibre Toxicology

The NLR Gene Family: A Standard Nomenclature

(2008) Jenny P.-Y. Ting et al.   IMMUNITY