TDP-43 upregulates lipid metabolism modulator ABHD2 to suppress apoptosis in hepatocellular carcinoma

Connecting TDP-43 Pathology with Neuropathy

(2021) Joseph R. Klim et al.   TRENDS IN NEUROSCIENCES

Molecular, functional, and pathological aspects of TDP-43 fragmentation

(2021) Deepak Chhangani et al.   iScience

Oncogenes, Proto-Oncogenes, and Lineage Restriction of Cancer Stem Cells

(2021) Geoffrey Brown   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Restoration of Mal overcomes the defects of apoptosis in lung cancer cells

(2020) Li-Tao Yang et al.   PLoS One

Role of oxidative stress in the pathogenesis of nonalcoholic fatty liver disease

(2020) Ze Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Lipid Metabolism in Development and Progression of Hepatocellular Carcinoma

(2020) Moris Sangineto et al.   Cancers

Hepatocellular carcinoma: old friends and new tricks

(2020) Eunsun Kim et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Aberrant lipid metabolism as a therapeutic target in liver cancer

(2019) Evans D. Pope et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The basis of clinicopathological heterogeneity in TDP-43 proteinopathy

(2019) Ito Kawakami et al.   ACTA NEUROPATHOLOGICA

Reprogramming of fatty acid metabolism in cancer

(2019) Nikos Koundouros et al.   BRITISH JOURNAL OF CANCER

Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease

(2018) Juan Pablo Arab et al.   Annual Review of Pathology-Mechanisms of Disease

Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer

(2018) Nikos Koundouros et al.   Frontiers in Oncology

Epidemiology and Management of Hepatocellular Carcinoma

(2018) Laura Kulik et al.   GASTROENTEROLOGY

TDP-43 regulates cancer-associated microRNAs

(2017) Xiaowei Chen et al.   Protein & Cell

Molecular characterization of human ABHD2 as TAG lipase and ester hydrolase

(2016) N. K. M. et al.   BIOSCIENCE REPORTS

Identification of TDP-43 as an oncogene in melanoma and its function during melanoma pathogenesis

(2016) Qinghai Zeng et al.   CANCER BIOLOGY & THERAPY

Abhydrolase domain containing 2, an androgen target gene, promotes prostate cancer cell proliferation and migration

(2016) Daisuke Obinata et al.   EUROPEAN JOURNAL OF CANCER

Mitochondria and Mitochondrial ROS in Cancer: Novel Targets for Anticancer Therapy

(2016) Yuhui Yang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Lipid metabolic reprogramming in cancer cells

(2016) S Beloribi-Djefaflia et al.   Oncogenesis

Lipid Metabolism, Apoptosis and Cancer Therapy

(2015) Chunfa Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Diagnostic Delays Are Common Among Patients With Hepatocellular Carcinoma

(2015) Nishant Patel et al.   Journal of the National Comprehensive Cancer Network

TDP-43 regulatesβ-adducin(Add2) transcript stability

(2015) Luisa Costessi et al.   RNA Biology

Mammalian alpha beta hydrolase domain (ABHD) proteins: Lipid metabolizing enzymes at the interface of cell signaling and energy metabolism

(2013) Caleb C. Lord et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520

(2013) Yun-Yong Park et al.   HEPATOLOGY

Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43

(2013) Peter J Lukavsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterizing TDP-43 interaction with its RNA targets

(2013) Amit Bhardwaj et al.   NUCLEIC ACIDS RESEARCH

TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes

(2012) Y. Kawahara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combining Clinical, Pathology, and Gene Expression Data to Predict Recurrence of Hepatocellular Carcinoma

(2011) Augusto Villanueva et al.   GASTROENTEROLOGY

TDP-43 functions and pathogenic mechanisms implicated in TDP-43 proteinopathies

(2011) Todd J. Cohen et al.   TRENDS IN MOLECULAR MEDICINE

Age-related pulmonary emphysema in mice lacking α/β hydrolase domain containing 2 gene

(2009) Shoude Jin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation

(2009) Erich B. Tahara et al.   FREE RADICAL BIOLOGY AND MEDICINE

Stromal gene expression predicts clinical outcome in breast cancer

(2008) Greg Finak et al.   NATURE MEDICINE

Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease

(2007) Emanuele Buratti   Frontiers in Bioscience-Landmark