Population genetics of clonally transmissible cancers

Mitochondrial genome sequencing of marine leukaemias reveals cancer contagion between clam species in the Seas of Southern Europe

(2022) Daniel Garcia-Souto et al.   eLife

Rapid and parallel adaptive mutations in spike S1 drive clade success in SARS-CoV-2

(2022) Kathryn E. Kistler et al.   Cell Host & Microbe

Survival and Detection of Bivalve Transmissible Neoplasia from the Soft-Shell Clam Mya arenaria (MarBTN) in Seawater

(2022) Rachael M. Giersch et al.   Pathogens

Phenotypic and molecular evolution across 10,000 generations in laboratory budding yeast populations

(2021) Milo S Johnson et al.   eLife

Spontaneous cell fusions as a mechanism of parasexual recombination in tumour cell populations

(2021) Daria Miroshnychenko et al.   Nature Ecology & Evolution

Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria

(2021) Jessika Consuegra et al.   Nature Communications

First description of a widespread Mytilus trossulus-derived bivalve transmissible cancer lineage in M. trossulus itself

(2021) Maria Skazina et al.   Scientific Reports

Prevalence and polymorphism of a mussel transmissible cancer in Europe

(2021) Maurine Hammel et al.   MOLECULAR ECOLOGY

Haplotype divergence supports long-term asexuality in the oribatid mite Oppiella nova

(2021) Alexander Brandt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The evolutionary dynamics and fitness landscape of clonal hematopoiesis

(2020) Caroline J. Watson et al.   SCIENCE

Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer

(2020) Andrea Strakova et al.   Nature Communications

Transmissible Cancers in an Evolutionary Perspective

(2020) Antoine M. Dujon et al.   iScience

A transmissible cancer shifts from emergence to endemism in Tasmanian devils

(2020) Austin H. Patton et al.   SCIENCE

Evolution and lineage dynamics of a transmissible cancer in Tasmanian devils

(2020) Young Mi Kwon et al.   PLOS BIOLOGY

Tracing the rise of malignant cell lines: distribution, epidemiology and evolutionary interactions of two transmissible cancers in Tasmanian devils

(2019) Samantha James et al.   Evolutionary Applications

Asexual reproduction reduces transposable element load in experimental yeast populations

(2019) Jens Bast et al.   eLife

Implementation of various approaches to study the prevalence, incidence and progression of disseminated neoplasia in mussel stocks

(2019) E.A.V. Burioli et al.   JOURNAL OF INVERTEBRATE PATHOLOGY

A single clonal lineage of transmissible cancer identified in two marine mussel species in South America and Europe

(2019) Marisa A Yonemitsu et al.   eLife

Principles and mechanisms of non-genetic resistance in cancer

(2019) Charles C. Bell et al.   BRITISH JOURNAL OF CANCER

The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils

(2018) Maximilian R. Stammnitz et al.   CANCER CELL

Density trends and demographic signals uncover the long-term impact of transmissible cancer in Tasmanian devils

(2018) Billie T. Lazenby et al.   JOURNAL OF APPLIED ECOLOGY

Horizontal transfer of retrotransposons between bivalves and other aquatic species of multiple phyla

(2018) Michael J. Metzger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The evolutionary history of dogs in the Americas

(2018) Máire Ní Leathlobhair et al.   SCIENCE

Clonal polymorphism and high heterozygosity in the celibate genome of the Amazon molly

(2018) Wesley C. Warren et al.   Nature Ecology & Evolution

The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer

(2018) Alison Caldwell et al.   eLife

Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution

(2018) Thomas O. McDonald et al.   NATURE GENETICS

Reply to ‘Neutral tumor evolution?’

(2018) Timon Heide et al.   NATURE GENETICS

Neutral tumor evolution?

(2018) Maxime Tarabichi et al.   NATURE GENETICS

Criticality in tumor evolution and clinical outcome

(2018) Erez Persi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Somatic mutant clones colonize the human esophagus with age

(2018) Iñigo Martincorena et al.   SCIENCE

Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures

(2017) Javad Noorbakhsh et al.   NATURE GENETICS

Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures

(2017) Marc J Williams et al.   NATURE GENETICS

Rapid evolution of the human mutation spectrum

(2017) Kelley Harris et al.   eLife

Sweepstake evolution revealed by population-genetic analysis of copy-number alterations in single genomes of breast cancer

(2017) Mamoru Kato et al.   Royal Society Open Science

Transmissible cancers in an evolutionary context

(2016) Beata Ujvari et al.   BIOESSAYS

Genetic Exchange among Bdelloid Rotifers Is More Likely Due to Horizontal Gene Transfer Than to Meiotic Sex

(2016) Nicolas Debortoli et al.   CURRENT BIOLOGY

Cancer: A disease at the crossroads of trade-offs

(2016) Camille Jacqueline et al.   Evolutionary Applications

Transmissible cancers, are they more common than thought?

(2016) Beata Ujvari et al.   Evolutionary Applications

Tempo and mode of genome evolution in a 50,000-generation experiment

(2016) Olivier Tenaillon et al.   NATURE

Widespread transmission of independent cancer lineages within multiple bivalve species

(2016) Michael J. Metzger et al.   NATURE

Genetic drift, selection and the evolution of the mutation rate

(2016) Michael Lynch et al.   NATURE REVIEWS GENETICS

Asexual Amoebae Escape Muller's Ratchet through Polyploidy

(2016) Sutherland K. Maciver   TRENDS IN PARASITOLOGY

Host–parasite coevolution: why changing population size matters

(2016) Andrei Papkou et al.   ZOOLOGY

Rapid evolutionary response to a transmissible cancer in Tasmanian devils

(2016) Brendan Epstein et al.   Nature Communications

Excess of mutational jackpot events in expanding populations revealed by spatial Luria–Delbrück experiments

(2016) Diana Fusco et al.   Nature Communications

A Sixth Modality of Infectious Disease: Contagious Cancer from Devils to Clams and Beyond

(2016) Michael J. Metzger et al.   PLoS Pathogens

Population genomics reveals the origin and asexual evolution of human infective trypanosomes

(2016) William Weir et al.   eLife

Horizontal Transmission of Clonal Cancer Cells Causes Leukemia in Soft-Shell Clams

(2015) Michael J. Metzger et al.   CELL

Field and laboratory transmission studies of haemic neoplasia in the soft-shell clam,Mya arenaria, from Atlantic Canada

(2015) D R Mateo et al.   JOURNAL OF FISH DISEASES

A second transmissible cancer in Tasmanian devils

(2015) Ruth J. Pye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High burden and pervasive positive selection of somatic mutations in normal human skin

(2015) I. Martincorena et al.   SCIENCE

Evolutionary Determinants of Cancer

(2015) M. Greaves   Cancer Discovery

The changing global distribution and prevalence of canine transmissible venereal tumour

(2014) Andrea Strakova et al.   BMC Veterinary Research

Activation of transcription and retrotransposition of a novel retroelement,Steamer, in neoplastic hemocytes of the molluskMya arenaria

(2014) Gloria Arriagada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tug-of-war between driver and passenger mutations in cancer and other adaptive processes

(2014) Christopher D. McFarland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage

(2014) E. P. Murchison et al.   SCIENCE

Punctuated Evolution of Prostate Cancer Genomes

(2013) Sylvan C. Baca et al.   CELL

Interplay between the Cancer Genome and Epigenome

(2013) Hui Shen et al.   CELL

Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma

(2013) Ruchi Shukla et al.   CELL

The haplotype-resolved genome and epigenome of the aneuploid HeLa cancer cell line

(2013) Andrew Adey et al.   NATURE

Genome dynamics during experimental evolution

(2013) Jeffrey E. Barrick et al.   NATURE REVIEWS GENETICS

Genomic signatures of selection at linked sites: unifying the disparity among species

(2013) Asher D. Cutter et al.   NATURE REVIEWS GENETICS

Population-genomic insights into the evolutionary origin and fate of obligately asexual Daphnia pulex

(2013) A. E. Tucker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experiments on the role of deleterious mutations as stepping stones in adaptive evolution

(2013) Arthur W. Covert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impact of deleterious passenger mutations on cancer progression

(2013) C. D. McFarland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-Term Dynamics of Adaptation in Asexual Populations

(2013) M. J. Wiser et al.   SCIENCE

Horizontal Gene Transfer Can Rescue Prokaryotes from Muller’s Ratchet: Benefit of DNA from Dead Cells and Population Subdivision

(2013) Nobuto Takeuchi et al.   G3-Genes Genomes Genetics

A Comparative Genomics Approach to Understanding Transmissible Cancer in Tasmanian Devils

(2012) Janine E. Deakin et al.   Annual Review of Genomics and Human Genetics

Genome Sequencing and Analysis of the Tasmanian Devil and Its Transmissible Cancer

(2012) Elizabeth P. Murchison et al.   CELL

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

Cancer in Light of Experimental Evolution

(2012) Kathleen Sprouffske et al.   CURRENT BIOLOGY

The Effects of Deleterious Mutations on Evolution at Linked Sites

(2012) Brian Charlesworth   GENETICS

Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load

(2012) S. Wielgoss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repeatability and Contingency in the Evolution of a Key Innovation in Phage Lambda

(2012) J. R. Meyer et al.   SCIENCE

Genomic Restructuring in the Tasmanian Devil Facial Tumour: Chromosome Painting and Gene Mapping Provide Clues to Evolution of a Transmissible Tumour

(2012) Janine E. Deakin et al.   PLoS Genetics

Chromosome Catastrophes Involve Replication Mechanisms Generating Complex Genomic Rearrangements

(2011) Pengfei Liu et al.   CELL

Is carcinogenesis a form of speciation?

(2011) Peter Duesberg et al.   CELL CYCLE

Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes

(2011) Tami D Lieberman et al.   NATURE GENETICS

Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data

(2011) Y. Tao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Capture by a Transmissible Cancer

(2011) C. A. Rebbeck et al.   SCIENCE

Recruitment of healthy mitochondria fuels transmissible cancers

(2011) Duur K. Aanen et al.   TRENDS IN GENETICS

Complementation, Genetic Conflict, and the Evolution of Sex and Recombination

(2010) M. Archetti   JOURNAL OF HEREDITY

Population genetics of cancer cell clones: possible implications of cancer stem cells

(2010) Christopher T Naugler   Theoretical Biology and Medical Modelling

Reduced Effectiveness of Selection Caused by a Lack of Recombination

(2009) Andrea J. Betancourt et al.   CURRENT BIOLOGY

THE ANIMAL WITHIN: CARCINOGENESIS AND THE CLONAL EVOLUTION OF CANCER CELLS ARE SPECIATION EVENTS SENSU STRICTO

(2009) Mark D. Vincent   EVOLUTION

ORIGINS AND EVOLUTION OF A TRANSMISSIBLE CANCER

(2009) Clare A. Rebbeck et al.   EVOLUTION

Genome evolution and adaptation in a long-term experiment with Escherichia coli

(2009) Jeffrey E. Barrick et al.   NATURE

Clonally transmissible cancers in dogs and Tasmanian devils

(2009) E P Murchison   ONCOGENE

Muller's Ratchet and compensatory mutation in Caenorhabditis briggsae mitochondrial genome evolution

(2008) Dana K Howe et al.   BMC EVOLUTIONARY BIOLOGY

Loss of Least-Loaded Class in Asexual Populations Due to Drift and Epistasis

(2008) K. Jain   GENETICS

Clonal Interference, Multiple Mutations and Adaptation in Large Asexual Populations

(2008) C. A. Fogle et al.   GENETICS

Evidence for degenerate tetraploidy in bdelloid rotifers

(2008) David B. Mark Welch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Massive Horizontal Gene Transfer in Bdelloid Rotifers

(2008) E. A. Gladyshev et al.   SCIENCE

Mitigating Mutational Meltdown in Mammalian Mitochondria

(2008) David M Rand   PLOS BIOLOGY