Sorafenib Chemosensitization by Caryophyllane Sesquiterpenes in Liver, Biliary, and Pancreatic Cancer Cells: The Role of STAT3/ABC Transporter Axis
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Sorafenib Chemosensitization by Caryophyllane Sesquiterpenes in Liver, Biliary, and Pancreatic Cancer Cells: The Role of STAT3/ABC Transporter Axis
Authors
Keywords
-
Journal
Pharmaceutics
Volume 14, Issue 6, Pages 1264
Publisher
MDPI AG
Online
2022-06-15
DOI
10.3390/pharmaceutics14061264
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Rescuing SLAMF3 Expression Restores Sorafenib Response in Hepatocellular Carcinoma Cells through the Induction of Mesenchymal-to-Epithelial Transition
- (2022) Grégory Fouquet et al. Cancers
- STAT1 and STAT3 Exhibit a Crosstalk and Are Associated with Increased Inflammation in Hepatocellular Carcinoma
- (2022) Carolin Ploeger et al. Cancers
- Gp130-Mediated STAT3 Activation Contributes to the Aggressiveness of Pancreatic Cancer through H19 Long Non-Coding RNA Expression
- (2022) Norihiko Sasaki et al. Cancers
- Harpagophytum procumbens Root Extract Mediates Anti-Inflammatory Effects in Osteoarthritis Synoviocytes through CB2 Activation
- (2022) Alessia Mariano et al. Pharmaceuticals
- Inhibition of STAT3Y705 phosphorylation by Stattic suppresses proliferation and induces mitochondrial-dependent apoptosis in pancreatic cancer cells
- (2022) Hangcheng Guo et al. Cell Death Discovery
- Multidrug resistance proteins (MRPs): Structure, function and the overcoming of cancer multidrug resistance
- (2021) Jing-Quan Wang et al. DRUG RESISTANCE UPDATES
- Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: an overview
- (2021) Maria Manuela Estevinho et al. CURRENT DRUG TARGETS
- Proteomics of colorectal cancer liver metastasis: A quantitative focus on drug elimination and pharmacodynamics effects
- (2021) Areti‐Maria Vasilogianni et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Induction of IL-6Rα by ATF3 enhances IL-6 mediated sorafenib and regorafenib resistance in hepatocellular carcinoma
- (2021) Zichan Dai et al. CANCER LETTERS
- Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects
- (2021) Sepideh Mirzaei et al. DRUG DISCOVERY TODAY
- Role of Caryophyllane Sesquiterpenes in the Entourage Effect of Felina 32 Hemp Inflorescence Phytocomplex in Triple Negative MDA-MB-468 Breast Cancer Cells
- (2021) Silvia Di Giacomo et al. MOLECULES
- ATP binding cassette transporters and cancer: revisiting their controversial role
- (2021) Parul Sharma et al. PHARMACOGENOMICS
- IL-6/STAT3 Is a Promising Therapeutic Target for Hepatocellular Carcinoma
- (2021) Junnv Xu et al. Frontiers in Oncology
- Potentiation of Low-Dose Doxorubicin Cytotoxicity by Affecting P-Glycoprotein through Caryophyllane Sesquiterpenes in HepG2 Cells: an in Vitro and in Silico Study
- (2020) Di Sotto et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Plasma Membrane Transporters as Biomarkers and Molecular Targets in Cholangiocarcinoma
- (2020) Jose J.G. Marin et al. Cells
- FOLFIRINOX vs gemcitabine/nab-paclitaxel for treatment of metastatic pancreatic cancer: Single-center cohort study
- (2020) In Rae Cho et al. World Journal of Gastrointestinal Oncology
- Looking for a Treatment for the Early Stage of Alzheimer’s Disease: Preclinical Evidence with Co-Ultramicronized Palmitoylethanolamide and Luteolin
- (2020) Roberta Facchinetti et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Modulation of STAT3 Signaling, Cell Redox Defenses and Cell Cycle Checkpoints by β-Caryophyllene in Cholangiocarcinoma Cells: Possible Mechanisms Accounting for Doxorubicin Chemosensitization and Chemoprevention
- (2020) Antonella Di Sotto et al. Cells
- New insights on sorafenib resistance in liver cancer with correlation of individualized therapy
- (2020) Zhang Cheng et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Drug resistance in cancer: mechanisms and tackling strategies
- (2020) Tanweer Haider et al. Pharmacological Reports
- IL-6/STAT3 Signaling Contributes to Sorafenib Resistance in Hepatocellular Carcinoma Through Targeting Cancer Stem Cells
- (2020) Yu Li et al. OncoTargets and Therapy
- Chemopreventive Potential of Caryophyllane Sesquiterpenes: An Overview of Preliminary Evidence
- (2020) Antonella Di Sotto et al. Cancers
- Chemosensitization of hepatocellular carcinoma cells to sorafenib by β-caryophyllene oxide-induced inhibition of ABC export pumps
- (2019) Silvia Di Giacomo et al. ARCHIVES OF TOXICOLOGY
- Signaling networks in cholangiocarcinoma: molecular pathogenesis, targeted therapies and drug resistance
- (2019) Laura Fouassier et al. LIVER INTERNATIONAL
- Causes of hOCT1‐Dependent Cholangiocarcinoma Resistance to Sorafenib and Sensitization by Tumor‐Selective Gene Therapy
- (2019) Elisa Lozano et al. HEPATOLOGY
- ERK is a Pivotal Player of Chemo-Immune-Resistance in Cancer
- (2019) Iris C. Salaroglio et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- β-caryophyllene, a dietary phytocannabinoid attenuates oxidative stress, inflammation, apoptosis and prevents structural alterations of the myocardium against doxorubicin-induced acute cardiotoxicity in rats: An in vitro and in vivo study
- (2019) Hasan Al-Taee et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Role of ATP-binding cassette transporters in cancer initiation and progression
- (2019) Stefania Nobili et al. SEMINARS IN CANCER BIOLOGY
- MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1-expressing cancer cells
- (2019) Christine C. Gana et al. BIOCHEMICAL PHARMACOLOGY
- The ABC subfamily A transporters: Multifaceted players with incipient potentialities in cancer
- (2019) Michela Pasello et al. SEMINARS IN CANCER BIOLOGY
- Protein Abundance of Hepatic Drug Transporters in Patients With Different Forms of Liver Damage
- (2019) Marek Drozdzik et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Chemoresistance and chemosensitization in cholangiocarcinoma
- (2018) Jose J.G. Marin et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- LncRNA-MALAT1 contributes to the cisplatin-resistance of lung cancer by upregulating MRP1 and MDR1 via STAT3 activation
- (2018) Zhixian Fang et al. BIOMEDICINE & PHARMACOTHERAPY
- Natural compounds and combination therapy in colorectal cancer treatment
- (2018) A. Rejhová et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Liver and pancreas: do similar embryonic development and tissue organization lead to similar mechanisms of tumorigenesis?
- (2018) Elsa Ghurburrun et al. GENE EXPRESSION
- TRIB2 knockdown as a regulator of chemotherapy resistance and proliferation via the ERK/STAT3 signaling pathway in human chronic myelogenous leukemia K562/ADM cells
- (2018) Xiancheng Ma et al. ONCOLOGY REPORTS
- Molecular bases of the poor response of liver cancer to chemotherapy
- (2018) Jose J.G. Marin et al. Clinics and Research in Hepatology and Gastroenterology
- ABC transporters as cancer drivers: Potential functions in cancer development
- (2018) Alice Domenichini et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- ATP-binding cassette transporters in progression and clinical outcome of pancreatic cancer: What is the way forward?
- (2018) Aleksandra Adamska et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Different Efflux Transporter Affinity and Metabolism of 99mTc-2-Methoxyisobutylisonitrile and 99mTc-Tetrofosmin for Multidrug Resistance Monitoring in Cancer
- (2018) Masato Kobayashi et al. PHARMACEUTICAL RESEARCH
- Signaling pathways as therapeutic targets in biliary tract cancer
- (2017) Jennifer Yang et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Molecular mechanisms of Sox transcription factors during the development of liver, bile duct, and pancreas
- (2017) Chunyue Yin SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Combinatorial immunotherapy strategies for hepatocellular carcinoma
- (2016) Maria Tagliamonte et al. CURRENT OPINION IN IMMUNOLOGY
- Impact of Membrane Drug Transporters on Resistance to Small-Molecule Tyrosine Kinase Inhibitors
- (2016) Claudia Neul et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Prognostic role of STAT3 in solid tumors: a systematic review and meta-analysis
- (2016) Pin Wu et al. Oncotarget
- MRP3 as a novel resistance factor for sorafenib in hepatocellular carcinoma
- (2016) Tetsu Tomonari et al. Oncotarget
- Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer
- (2015) Nagaraj S. Nagathihalli et al. GASTROENTEROLOGY
- CSN5 silencing reverses sorafenib resistance of human hepatocellular carcinoma HepG2 cells
- (2015) HAIBO WANG et al. Molecular Medicine Reports
- Multidisciplinary Approach to Determine the Optimal Time and Period for Extracting the Essential Oil from Mentha suaveolens Ehrh
- (2015) Stefania Garzoli et al. MOLECULES
- Loss of runt-related transcription factor 3 induces gemcitabine resistance in pancreatic cancer
- (2013) Shigeru Horiguchi et al. Molecular Oncology
- Reversal of Multidrug Resistance by Gefitinib Via RAF1/ERK Pathway in Pancreatic Cancer Cell Line
- (2012) Zhi Xiao et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- Influence of Serum in Hemodialysis Patients on the Expression of Intestinal and Hepatic Transporters for the Excretion of Pravastatin
- (2012) Masayuki Tsujimoto et al. THERAPEUTIC APHERESIS AND DIALYSIS
- Stat3 and MMP7 Contribute to Pancreatic Ductal Adenocarcinoma Initiation and Progression
- (2011) Akihisa Fukuda et al. CANCER CELL
- Abcg2 Overexpression Represents a Novel Mechanism for Acquired Resistance to the Multi-Kinase Inhibitor Danusertib in BCR-ABL-Positive Cells In Vitro
- (2011) Stefan Balabanov et al. PLoS One
- Sorafenib Inhibits STAT3 Activation to Enhance TRAIL-Mediated Apoptosis in Human Pancreatic Cancer Cells
- (2010) S. Huang et al. MOLECULAR CANCER THERAPEUTICS
- Cellular Mechanisms of Resistance to Anthracyclines and Taxanes in Cancer: Intrinsic and Acquired
- (2008) A. Jo Chien et al. SEMINARS IN ONCOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More