Chemosensitization of hepatocellular carcinoma cells to sorafenib by β-caryophyllene oxide-induced inhibition of ABC export pumps

Chemoresistance and chemosensitization in cholangiocarcinoma

(2018) Jose J.G. Marin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Caryophyllane sesquiterpenes inhibit DNA-damage by tobacco smoke in bacterial and mammalian cells

(2018) Silvia Di Giacomo et al.   FOOD AND CHEMICAL TOXICOLOGY

Anti-inflammatory and anti-edematogenic action of the Croton campestris A. St.-Hil (Euphorbiaceae) essential oil and the compound β-caryophyllene in in vivo models

(2018) Cícera Datiane de Morais Oliveira-Tintino et al.   PHYTOMEDICINE

Molecular bases of the poor response of liver cancer to chemotherapy

(2018) Jose J.G. Marin et al.   Clinics and Research in Hepatology and Gastroenterology

Relevance of Two Genes in the Multidrug Resistance of Hepatocellular Carcinoma: In Vivo and Clinical Studies

(2018) Zhengang Sun et al.   TUMORI

In vitro and in vivo antimalarial potential of oleoresin obtained from Copaifera reticulata Ducke (Fabaceae) in the Brazilian Amazon rainforest

(2017) Giovana A.G. de Souza et al.   PHYTOMEDICINE

Quizartinib (AC220) reverses ABCG2-mediated multidrug resistance: In vitro and in vivo studies

(2017) Jun Li et al.   Oncotarget

Anticonvulsant activity of β-caryophyllene against pentylenetetrazol-induced seizures

(2016) Cleide Correia de Oliveira et al.   EPILEPSY & BEHAVIOR

HOXB4 knockdown reverses multidrug resistance of human myelogenous leukemia K562/ADM cells by downregulating P-gp, MRP1 and BCRP expression via PI3K/Akt signaling pathway

(2016) Hong Wang et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

NFκBP65 transcription factor modulates resistance to doxorubicin through ABC transporters in breast cancer

(2016) Kobra Velaei et al.   Breast Cancer

MRP3 as a novel resistance factor for sorafenib in hepatocellular carcinoma

(2016) Tetsu Tomonari et al.   Oncotarget

Alpha fetoprotein antagonizes apoptosis induced by paclitaxel in hepatoma cells in vitro

(2016) Mingyue Zhu et al.   Scientific Reports

Activation of c-Jun predicts a poor response to sorafenib in hepatocellular carcinoma: Preliminary Clinical Evidence

(2016) Wei Chen et al.   Scientific Reports

Potential molecular, cellular and microenvironmental mechanism of sorafenib resistance in hepatocellular carcinoma

(2015) Jiang Chen et al.   CANCER LETTERS

Mutagenicity of cigarette butt waste in the bacterial reverse mutation assay: The protective effects of β-caryophyllene and β-caryophyllene oxide

(2015) Silvia Di Giacomo et al.   ENVIRONMENTAL TOXICOLOGY

Enhanced antitumour drug delivery to cholangiocarcinoma through the apical sodium-dependent bile acid transporter (ASBT)

(2015) Elisa Lozano et al.   JOURNAL OF CONTROLLED RELEASE

CSN5 silencing reverses sorafenib resistance of human hepatocellular carcinoma HepG2 cells

(2015) HAIBO WANG et al.   Molecular Medicine Reports

The Influence of Sesquiterpenes from Myrica rubra on the Antiproliferative and Pro-Oxidative Effects of Doxorubicin and Its Accumulation in Cancer Cells

(2015) Martin Ambrož et al.   MOLECULES

Hepatocellular Carcinoma: Reasons for Phase III Failure and Novel Perspectives on Trial Design

(2014) J. M. Llovet et al.   CLINICAL CANCER RESEARCH

β-Caryophyllene oxide potentiates TNFα-induced apoptosis and inhibits invasion through down-modulation of NF-κB-regulated gene products

(2013) Chulwon Kim et al.   APOPTOSIS

Expression ofSLC22A1variants may affect the response of hepatocellular carcinoma and cholangiocarcinoma to sorafenib

(2013) Elisa Herraez et al.   HEPATOLOGY

Targeting therapy of hepatocellular carcinoma with doxorubicin prodrug PDOX increases anti-metastatic effect and reduces toxicity: a preclinical study

(2013) Qun Wang et al.   Journal of Translational Medicine

Genotoxicity assessment of β-caryophyllene oxide

(2013) Antonella Di Sotto et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Cisplatin-Induced Chemoresistance in Colon Cancer Cells Involves FXR-Dependent and FXR-Independent Up-Regulation of ABC Proteins

(2012) Elisa Herraez et al.   MOLECULAR PHARMACEUTICS

Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents

(2012) Michael Wink et al.   Frontiers in Microbiology

β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation

(2011) Kyung-Ran Park et al.   CANCER LETTERS

Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance?

(2011) Anna Brózik et al.   Expert Opinion on Drug Metabolism & Toxicology

Synergy research: Approaching a new generation of phytopharmaceuticals

(2010) Hildebert Wagner   FITOTERAPIA

Expression of multidrug resistance-associated protein 1 in hepatocellular carcinoma is associated with a more aggressive tumour phenotype and may reflect a progenitor cell origin

(2010) Sara Vander Borght et al.   LIVER INTERNATIONAL

Evolutionary Advantage and Molecular Modes of Action of Multi-Component Mixtures Used in Phytomedicine

(2008) Michael Wink   CURRENT DRUG METABOLISM

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE