No bidirectional relationship between depression and periodontitis: A genetic correlation and Mendelian randomization study

The Role of the Oral Microbiota Related to Periodontal Diseases in Anxiety, Mood and Trauma- and Stress-Related Disorders

(2022) María Martínez et al.   Frontiers in Psychiatry

Periodontal diseases and depression: A preclinical in vivo study

(2021) María Martínez et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Role of microbes in the pathogenesis of neuropsychiatric disorders

(2021) Aranyak Goswami et al.   FRONTIERS IN NEUROENDOCRINOLOGY

The psychobiological links between chronic stress‐related diseases, periodontal/peri‐implant diseases, and wound healing

(2021) Ann M. Decker et al.   PERIODONTOLOGY 2000

Interpreting Mendelian-randomization estimates of the effects of categorical exposures such as disease status and educational attainment

(2021) Laurence J Howe et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Methods of Public Health Research — Strengthening Causal Inference from Observational Data

(2021) Miguel A. Hernán   NEW ENGLAND JOURNAL OF MEDICINE

Simultaneous estimation of bi-directional causal effects and heritable confounding from GWAS summary statistics

(2021) Liza Darrous et al.   Nature Communications

Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration

(2021) Veronika W Skrivankova et al.   BMJ-British Medical Journal

Global, Regional, and National Levels and Trends in Burden of Oral Conditions from 1990 to 2017: A Systematic Analysis for the Global Burden of Disease 2017 Study

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Mendelian randomization accounting for correlated and uncorrelated pleiotropic effects using genome-wide summary statistics

(2020) Jean Morrison et al.   NATURE GENETICS

Polygenic Mendelian Randomization

(2020) Frank Dudbridge   Cold Spring Harbor Perspectives in Medicine

Inflammasomes as contributors to periodontal disease

(2020) Julie T. Marchesan   JOURNAL OF PERIODONTOLOGY

Understanding the relationship between type 2 diabetes and depression: lessons from genetically informative study designs

(2020) R. S. Bergmans et al.   DIABETIC MEDICINE

Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis

(2020) Simon Haworth et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Periodontal disease and emotional disorders: A meta‐analysis

(2020) De‐Xiu Zheng et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms

(2020) Nils Kappelmann et al.   JAMA Psychiatry

Comorbid depression in medical diseases

(2020) Stefan M. Gold et al.   Nature Reviews Disease Primers

Impact of systemic factors in shaping the periodontal microbiome

(2020) Flavia Teles et al.   PERIODONTOLOGY 2000

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

(2019) David M. Howard et al.   NATURE NEUROSCIENCE

Porphyromonas gingivalis induces depression via downregulating p75NTR-mediated BDNF maturation in astrocytes

(2019) Yi-Xi Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

Commentary: Orienting causal relationships between two phenotypes using bidirectional Mendelian randomization

(2019) Rebecca C Richmond et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data

(2019) Dmitry Shungin et al.   Nature Communications

The assessment of stress, depression, and inflammation as a collective risk factor for periodontal diseases: a systematic review

(2019) Ann Decker et al.   Clinical Oral Investigations

Prospective biomarkers of major depressive disorder: a systematic review and meta-analysis

(2019) Mitzy Kennis et al.   MOLECULAR PSYCHIATRY

The cytokine network involved in the host immune response to periodontitis

(2019) Weiyi Pan et al.   International Journal of Oral Science

Evaluating the potential role of pleiotropy in Mendelian randomization studies

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Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions

(2018) Panos N. Papapanou et al.   JOURNAL OF PERIODONTOLOGY

A meta-analysis of emotional disorders as possible risk factors for chronic periodontitis

(2018) Fei Liu et al.   MEDICINE

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

Implications of Systemic Inflammation and Periodontitis for Major Depression

(2018) Sadayuki Hashioka et al.   Frontiers in Neuroscience

Is depression associated with oral health outcomes in adults and elders? A systematic review and meta-analysis

(2018) Mariana Gonzalez Cademartori et al.   Clinical Oral Investigations

Mendelian randomization with a binary exposure variable: interpretation and presentation of causal estimates

(2018) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Chronic oral application of a periodontal pathogen results in brain inflammation, neurodegeneration and amyloid beta production in wild type mice

(2018) Vladimir Ilievski et al.   PLoS One

Is there an association between depression and periodontitis? A birth cohort study

(2018) Gustavo G. Nascimento et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Distinguishing genetic correlation from causation across 52 diseases and complex traits

(2018) Luke J. O’Connor et al.   NATURE GENETICS

The oral microbiota: dynamic communities and host interactions

(2018) Richard J. Lamont et al.   NATURE REVIEWS MICROBIOLOGY

Interaction of lifestyle, behaviour or systemic diseases with dental caries and periodontal diseases: consensus report of group 2 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases

(2017) Iain L.C. Chapple et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Bivariate Genome-Wide Association Study of Depressive Symptoms with Type 2 Diabetes and Quantitative Glycemic Traits

(2017) Kadri Haljas et al.   PSYCHOSOMATIC MEDICINE

Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

(2017) Yuri Milaneschi et al.   JAMA Psychiatry

Psychological side effects of immune therapies: symptoms and pathomechanism

(2016) David Kovacs et al.   CURRENT OPINION IN PHARMACOLOGY

The oral health of people with anxiety and depressive disorders – a systematic review and meta-analysis

(2016) Steve Kisely et al.   JOURNAL OF AFFECTIVE DISORDERS

Association between depression and periodontitis: a systematic review and meta-analysis

(2016) Milena Moreira Araújo et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Causal inference and longitudinal data: a case study of religion and mental health

(2016) Tyler J. VanderWeele et al.   SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY

Approximately independent linkage disequilibrium blocks in human populations

(2015) Tomaz Berisa et al.   BIOINFORMATICS

Association of Periodontitis and Subsequent Depression

(2015) Chih-Chao Hsu et al.   MEDICINE

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Calculating statistical power in Mendelian randomization studies

(2013) Marie-Jo A Brion et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY