Assessment and visualization of phenome-wide causal relationships using genetic data: an application to dental caries and periodontitis

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

(2019) Simon Haworth et al.   Nature Communications

Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

(2019) Jane Armitage et al.   LANCET

Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?

(2019) Daniel John Lawson et al.   HUMAN GENETICS

Mendelian randomization: the challenge of unobserved environmental confounds

(2019) Philipp D Koellinger et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Oral diseases: a global public health challenge

(2019) Marco A Peres et al.   LANCET

Ending the neglect of global oral health: time for radical action

(2019) Richard G Watt et al.   LANCET

Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data

(2019) Dmitry Shungin et al.   Nature Communications

Causal association between periodontitis and hypertension: evidence from Mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy

(2019) Marta Czesnikiewicz-Guzik et al.   EUROPEAN HEART JOURNAL

Exploring the association of genetic factors with participation in the Avon Longitudinal Study of Parents and Children

(2018) Amy E Taylor et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

Using genetic data to strengthen causal inference in observational research

(2018) Jean-Baptiste Pingault et al.   NATURE REVIEWS GENETICS

Vitamin D status and dental caries in healthy Swedish children

(2018) Johanna Gyll et al.   Nutrition Journal

The nature of nurture: Effects of parental genotypes

(2018) Augustine Kong et al.   SCIENCE

Causal associations between risk factors and common diseases inferred from GWAS summary data

(2018) Zhihong Zhu et al.   Nature Communications

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Distinguishing genetic correlation from causation across 52 diseases and complex traits

(2018) Luke J. O’Connor et al.   NATURE GENETICS

Interpreting findings from Mendelian randomization using the MR-Egger method

(2017) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Interaction of lifestyle, behaviour or systemic diseases with dental caries and periodontal diseases: consensus report of group 2 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases

(2017) Iain L.C. Chapple et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Racial differences in periodontal disease and 10-year self-reported tooth loss among late middle-aged and older adults: the dental ARIC study

(2017) S. Naorungroj et al.   JOURNAL OF PUBLIC HEALTH DENTISTRY

Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy

(2017) Jessica M. B. Rees et al.   STATISTICS IN MEDICINE

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Bias due to participant overlap in two-sample Mendelian randomization

(2016) Stephen Burgess et al.   GENETIC EPIDEMIOLOGY

Commentary: Two-sample Mendelian randomization: opportunities and challenges

(2016) Debbie A Lawlor   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Keratins as components of the enamel organic matrix

(2016) Olivier Duverger et al.   MATRIX BIOLOGY

Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium

(2015) D. Shungin et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The fine-scale genetic structure of the British population

(2015) Stephen Leslie et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Re-Examining the Association between Vitamin D and Childhood Caries

(2015) Tom Dudding et al.   PLoS One

Hair keratin mutations in tooth enamel increase dental decay risk

(2014) Olivier Duverger et al.   JOURNAL OF CLINICAL INVESTIGATION

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE