Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots
Published 2022 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots
Authors
Keywords
-
Journal
Nature Communications
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-06-30
DOI
10.1038/s41467-022-30931-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank
- (2022) Sean J. Jurgens et al. NATURE GENETICS
- Genetics of 35 blood and urine biomarkers in the UK Biobank
- (2021) Nasa Sinnott-Armstrong et al. NATURE GENETICS
- ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy
- (2021) Jae-Sung You et al. Cell Reports
- A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density
- (2021) Nasa Sinnott-Armstrong et al. Cell Metabolism
- Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile
- (2021) Adrian H. Heald et al. DIABETIC MEDICINE
- Genetic evidence for different adiposity phenotypes and their opposing influence on ectopic fat and risk of cardiometabolic disease
- (2021) Susan Martin et al. DIABETES
- Computationally efficient whole-genome regression for quantitative and binary traits
- (2021) Joelle Mbatchou et al. NATURE GENETICS
- Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank
- (2021) Joseph D. Szustakowski et al. NATURE GENETICS
- Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning
- (2021) Yi Liu et al. eLife
- Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape
- (2021) Jonathan Sulc et al. Communications Biology
- The mutational constraint spectrum quantified from variation in 141,456 humans
- (2020) Konrad J. Karczewski et al. NATURE
- The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions
- (2020) Thomas J. Littlejohns et al. Nature Communications
- RSPO3 impacts body fat distribution and regulates adipose cell biology in vitro
- (2020) Nellie Y. Loh et al. Nature Communications
- Distinct abdominal and gluteal adipose tissue transcriptome signatures are altered by exercise training in African women with obesity
- (2020) Pamela A. Nono Nankam et al. Scientific Reports
- Causes, consequences, and treatment of metabolically unhealthy fat distribution
- (2020) Norbert Stefan Lancet Diabetes & Endocrinology
- LDpred2: better, faster, stronger
- (2020) Florian Privé et al. BIOINFORMATICS
- Association of genetic variation with cirrhosis: a multi-trait genome-wide association and gene-environment interaction study
- (2020) Connor A. Emdin et al. GASTROENTEROLOGY
- Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects
- (2019) Mathias Rask-Andersen et al. Nature Communications
- Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
- (2019) Anne E. Justice et al. NATURE GENETICS
- Association between regional body fat and cardiovascular disease risk among postmenopausal women with normal body mass index
- (2019) Guo-Chong Chen et al. EUROPEAN HEART JOURNAL
- A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity
- (2019) Jonathan P Bradfield et al. HUMAN MOLECULAR GENETICS
- Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration
- (2019) Henry R. Wilman et al. JOURNAL OF HEPATOLOGY
- Contribution of genetics to visceral adiposity and its relation to cardiovascular and metabolic disease
- (2019) Torgny Karlsson et al. NATURE MEDICINE
- Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes
- (2019) Zhifen Chen et al. CIRCULATION RESEARCH
- Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank
- (2019) Zhaozhong Zhu et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Sex Differences in Genomic Drivers of Adipose Distribution and Related Cardiometabolic Disorders
- (2019) Heidi S. Lumish et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Mixed-model association for biobank-scale datasets
- (2018) Po-Ru Loh et al. NATURE GENETICS
- Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
- (2018) Hilary K. Finucane et al. NATURE GENETICS
- Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease
- (2018) Connor A. Emdin et al. Nature Communications
- “Fat Shadows” From DXA for the Qualitative Assessment of Lipodystrophy: When a Picture Is Worth a Thousand Numbers
- (2018) Rasimcan Meral et al. DIABETES CARE
- Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry
- (2018) Sara L Pulit et al. HUMAN MOLECULAR GENETICS
- Genes that make you fat, but keep you healthy
- (2018) Ruth J.F. Loos et al. JOURNAL OF INTERNAL MEDICINE
- Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies
- (2018) Wei Zhou et al. NATURE GENETICS
- Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis
- (2018) Miriam S. Udler et al. PLOS MEDICINE
- Genome-Wide and Abdominal MRI Data Provide Evidence That a Genetically Determined Favorable Adiposity Phenotype Is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease, and Hypertension
- (2018) Yingjie Ji et al. DIABETES
- DNA Sequence Variation in ACVR1C Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes
- (2018) Connor A. Emdin et al. DIABETES
- Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors
- (2018) Luca A. Lotta et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The UK Biobank resource with deep phenotyping and genomic data
- (2018) Clare Bycroft et al. NATURE
- Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
- (2018) Anubha Mahajan et al. NATURE GENETICS
- The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
- (2018) Annalisa Buniello et al. NUCLEIC ACIDS RESEARCH
- Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease
- (2017) Connor A. Emdin et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease
- (2017) Amit V. Khera et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Non-alcoholic fatty liver disease is an influencing factor for the association of SHBG with metabolic syndrome in diabetes patients
- (2017) Xiaomin Hua et al. Scientific Reports
- Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease
- (2017) Pim van der Harst et al. CIRCULATION RESEARCH
- A Robust Example of Collider Bias in a Genetic Association Study
- (2016) Felix R. Day et al. AMERICAN JOURNAL OF HUMAN GENETICS
- VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications
- (2016) Marius R. Robciuc et al. Cell Metabolism
- Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease
- (2016) Hanieh Yaghootkar et al. DIABETES
- dbNSFP v3.0: A One-Stop Database of Functional Predictions and Annotations for Human Nonsynonymous and Splice-Site SNVs
- (2016) Xiaoming Liu et al. HUMAN MUTATION
- Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia
- (2016) Amit V. Khera et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance
- (2016) Luca A Lotta et al. NATURE GENETICS
- Multiethnic genome-wide meta-analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation
- (2016) Audrey Y Chu et al. NATURE GENETICS
- Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
- (2016) Zhihong Zhu et al. NATURE GENETICS
- Integrative approaches for large-scale transcriptome-wide association studies
- (2016) Alexander Gusev et al. NATURE GENETICS
- A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
- (2016) Janina S. Ried et al. Nature Communications
- The Ensembl gene annotation system
- (2016) Bronwen L. Aken et al. Database-The Journal of Biological Databases and Curation
- Adjusting for Heritable Covariates Can Bias Effect Estimates in Genome-Wide Association Studies
- (2015) Hugues Aschard et al. AMERICAN JOURNAL OF HUMAN GENETICS
- MAFB as a novel regulator of human adipose tissue inflammation
- (2015) Annie M. L. Pettersson et al. DIABETOLOGIA
- New genetic loci link adipose and insulin biology to body fat distribution
- (2015) Dmitry Shungin et al. NATURE
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- Genetic studies of body mass index yield new insights for obesity biology
- (2015) Adam E. Locke et al. NATURE
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- Gene expression analysis identifies global gene dosage sensitivity in cancer
- (2015) Rudolf S N Fehrmann et al. NATURE GENETICS
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- Efficient Bayesian mixed-model analysis increases association power in large cohorts
- (2015) Po-Ru Loh et al. NATURE GENETICS
- A gene-based association method for mapping traits using reference transcriptome data
- (2015) Eric R Gamazon et al. NATURE GENETICS
- The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
- (2015) et al. SCIENCE
- Biological interpretation of genome-wide association studies using predicted gene functions
- (2015) Tune H. Pers et al. Nature Communications
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
- (2015) Cathie Sudlow et al. PLOS MEDICINE
- Second-generation PLINK: rising to the challenge of larger and richer datasets
- (2015) Christopher C Chang et al. GigaScience
- Rare-Variant Association Analysis: Study Designs and Statistical Tests
- (2014) Seunggeung Lee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- EasyStrata: evaluation and visualization of stratified genome-wide association meta-analysis data
- (2014) Thomas W. Winkler et al. BIOINFORMATICS
- Toward better understanding of artifacts in variant calling from high-coverage samples
- (2014) Heng Li BIOINFORMATICS
- Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss
- (2014) Harish Dharuri et al. DIABETOLOGIA
- Effect of Tesamorelin on Visceral Fat and Liver Fat in HIV-Infected Patients With Abdominal Fat Accumulation
- (2014) Takara L. Stanley et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
- (2014) Ron Do et al. NATURE
- MutationTaster2: mutation prediction for the deep-sequencing age
- (2014) Jana Marie Schwarz et al. NATURE METHODS
- CrossMap: a versatile tool for coordinate conversion between genome assemblies
- (2013) Hao Zhao et al. BIOINFORMATICS
- Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
- (2013) Joshua C. Randall et al. PLoS Genetics
- Agreement of bioelectrical impedance with dual-energy X-ray absorptiometry and MRI to estimate changes in body fat, skeletal muscle and visceral fat during a 12-month weight loss intervention
- (2012) Kirsi H. Pietiläinen et al. BRITISH JOURNAL OF NUTRITION
- Metabolic Effects of a Growth Hormone-Releasing Factor in Obese Subjects with Reduced Growth Hormone Secretion: A Randomized Controlled Trial
- (2012) Hideo Makimura et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women
- (2012) Caroline S. Fox et al. PLoS Genetics
- Accuracy of direct segmental multi-frequency bioimpedance analysis in the assessment of total body and segmental body composition in middle-aged adult population
- (2011) Carolina H.Y. Ling et al. CLINICAL NUTRITION
- Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
- (2011) Tuomas O Kilpeläinen et al. NATURE GENETICS
- Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants
- (2011) J.-H. Park et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Absolute value of visceral fat area measured on computed tomography scans and obesity-related cardiovascular risk factors in large-scale Japanese general population (the VACATION-J study)
- (2010) Aki Hiuge-Shimizu et al. ANNALS OF MEDICINE
- Robust relationship inference in genome-wide association studies
- (2010) Ani Manichaikul et al. BIOINFORMATICS
- Vascular endothelial growth factor B controls endothelial fatty acid uptake
- (2010) Carolina E. Hagberg et al. NATURE
- A method and server for predicting damaging missense mutations
- (2010) Ivan A Adzhubei et al. NATURE METHODS
- Identification of deleterious mutations within three human genomes
- (2009) S. Chun et al. GENOME RESEARCH
- Identification of a Role for the ARHGEF3 Gene in Postmenopausal Osteoporosis
- (2008) Ben H. Mullin et al. AMERICAN JOURNAL OF HUMAN GENETICS
- SERPINA1 Gene Variants in Individuals from the General Population with Reduced 1-Antitrypsin Concentrations
- (2008) M. Zorzetto et al. CLINICAL CHEMISTRY
- Patterns of Abdominal Fat Distribution: The Framingham Heart Study
- (2008) K. M. Pou et al. DIABETES CARE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started