Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

Control for Population Structure and Relatedness for Binary Traits in Genetic Association Studies via Logistic Mixed Models

(2016) Han Chen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

General Methods for Evolutionary Quantitative Genetic Inference from Generalized Mixed Models

(2016) P. de Villemereuil et al.   GENETICS

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Unravelling the human genome–phenome relationship using phenome-wide association studies

(2016) William S. Bush et al.   NATURE REVIEWS GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Advantages and pitfalls in the application of mixed-model association methods

(2014) Jian Yang et al.   NATURE GENETICS

Recommended Joint and Meta-Analysis Strategies for Case-Control Association Testing of Single Low-Count Variants

(2013) Clement Ma et al.   GENETIC EPIDEMIOLOGY

A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects

(2013) Khader Shameer et al.   HUMAN GENETICS

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

(2013) Joshua C Denny et al.   NATURE BIOTECHNOLOGY

Rapid variance components–based method for whole-genome association analysis

(2012) Gulnara R Svishcheva et al.   NATURE GENETICS

Genome-wide efficient mixed-model analysis for association studies

(2012) Xiang Zhou et al.   NATURE GENETICS

Improved linear mixed models for genome-wide association studies

(2012) Jennifer Listgarten et al.   NATURE METHODS

FaST linear mixed models for genome-wide association studies

(2011) Christoph Lippert et al.   NATURE METHODS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mixed linear model approach adapted for genome-wide association studies

(2010) Zhiwu Zhang et al.   NATURE GENETICS

Variance component model to account for sample structure in genome-wide association studies

(2010) Hyun Min Kang et al.   NATURE GENETICS

Genetic Structure of Europeans: A View from the North–East

(2009) Mari Nelis et al.   PLoS One