ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy

Autophagy as a Therapeutic Target to Enhance Aged Muscle Regeneration

(2019) David Lee et al.   Cells

Disruption of both ROCK1 and ROCK2 genes in cardiomyocytes promotes autophagy and reduces cardiac fibrosis during aging

(2019) Jianjian Shi et al.   FASEB JOURNAL

A DGKζ-FoxO-ubiquitin proteolytic axis controls fiber size during skeletal muscle remodeling

(2018) Jae-Sung You et al.   Science Signaling

Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity

(2018) Jianjian Shi et al.   Oncotarget

Attenuation of autophagy impacts on muscle fibre development, starvation induced stress and fibre regeneration following acute injury

(2018) Andrea Paolini et al.   Scientific Reports

A DGKζ-FoxO-ubiquitin proteolytic axis controls fiber size during skeletal muscle remodeling

(2018) Jae-Sung You et al.   Science Signaling

Autophagy and disease

(2017) Andrew Thorburn   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy regulates satellite cell ability to regenerate normal and dystrophic muscles

(2016) E Fiacco et al.   CELL DEATH AND DIFFERENTIATION

Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway

(2016) David Sebastián et al.   EMBO JOURNAL

Autophagy maintains stemness by preventing senescence

(2016) Laura García-Prat et al.   NATURE

AMPK Activation of Muscle Autophagy Prevents Fasting-Induced Hypoglycemia and Myopathy during Aging

(2015) Adam L. Bujak et al.   Cell Metabolism

Autophagy Impairment in Muscle Induces Neuromuscular Junction Degeneration and Precocious Aging

(2014) Silvia Carnio et al.   Cell Reports

Transcription activator-like effector nucleases (TALENs): A highly efficient and versatile tool for genome editing

(2013) Ning Sun et al.   BIOTECHNOLOGY AND BIOENGINEERING

RhoA mediates defective stem cell function and heterotopic ossification in dystrophic muscle of mice

(2013) Xiaodong Mu et al.   FASEB JOURNAL

Motor Unit Changes Seen With Skeletal Muscle Sarcopenia in Oldest Old Rats

(2013) T. A. Kung et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

XPLN is an endogenous inhibitor of mTORC2

(2013) N. Khanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of autophagosome formation by Rho kinase

(2012) Andrzej Mleczak et al.   CELLULAR SIGNALLING

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

(2012) R. C. Wang et al.   SCIENCE

Evolving concepts on the age-related changes in “muscle quality”

(2012) David W. Russ et al.   Journal of Cachexia Sarcopenia and Muscle

Regulatory interactions between muscle and the immune system during muscle regeneration

(2010) James G. Tidball et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging

(2010) Fabio Demontis et al.   CELL

The Akt activation inhibitor TCN-P inhibits Akt phosphorylation by binding to the PH domain of Akt and blocking its recruitment to the plasma membrane

(2010) N Berndt et al.   CELL DEATH AND DIFFERENTIATION

Relationships between motor unit size and recruitment threshold in older adults: implications for size principle

(2009) Brett W. Fling et al.   EXPERIMENTAL BRAIN RESEARCH

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

(2008) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling

(2008) Tsuneo Ikenoue et al.   EMBO JOURNAL

Rho/Rho-associated Kinase Signal Regulates Myogenic Differentiation via Myocardin-related Transcription Factor-A/Smad-dependent Transcription of theId3Gene

(2008) Kazuhiro Iwasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY