Synthesis, characterization and molecular docking of novel lonazolac analogues 3-(3-hydroxy-5-methyl-1H-pyrazol-4-yl)-3-arylpropanoic acid derivatives: Highly potential COX-1/COX-2, matrix metalloproteinase and protein denaturation inhibitors

Synthesis, Inhibitory Activity, and In Silico Modeling of Selective COX-1 Inhibitors with a Quinazoline Core

(2021) Marcela Dvorakova et al.   ACS Medicinal Chemistry Letters

Chemical Perspective of the Mechanism of Action of Antiamyloidogenic Compounds Using a Minimalistic Peptide as a Reductionist Model

(2021) Bharti Koshti et al.   ACS Chemical Neuroscience

Design, synthesis, biological evaluation, and computational studies of novel thiazolo-pyrazole hybrids as promising selective COX-2 inhibitors: Implementation of apoptotic genes expression for ulcerogenic liability assessment

(2021) Adel A. Marzouk et al.   BIOORGANIC CHEMISTRY

A Compendium of the Most Promising Synthesized Organic Compounds against Several Fusarium oxysporum Species: Synthesis, Antifungal Activity, and Perspectives

(2021) Paola Borrego-Muñoz et al.   MOLECULES

Indirect, catalyst free β-arylation of acyclic 1,5-dicarbonyl compounds via green method

(2021) Parashuram Gudimani et al.   Chemical Data Collections

Rational design, synthesis and SAR study of novel warfarin analogous of 4-hydroxy coumarin-beta-aryl propanoic acid derivatives as potent anti-inflammatory agents

(2021) Varsha Pawar et al.   JOURNAL OF MOLECULAR STRUCTURE

Novel Anticancer Fused Pyrazole Derivatives as EGFR and VEGFR-2 Dual TK Inhibitors

(2020) Nashwa M. Saleh et al.   Frontiers in Chemistry

The selective condensation of pyrazolones to isatins in aqueous medium

(2019) Yong Zhang et al.   TETRAHEDRON

Pyrazole, pyrazolone and enaminonitrile pyrazole derivatives: Synthesis, characterization and potential in corrosion inhibition and antimicrobial applications

(2018) Galal H. Sayed et al.   JOURNAL OF MOLECULAR LIQUIDS

A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly

(2018) Supakanya Wongrakpanich et al.   Aging and Disease

Tautomerism and antioxidant activity of some 4-acylpyrazolone-based Schiff bases: a theoretical study

(2018) Esam A. Orabi   RSC Advances

Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6)

(2017) Gino Cingolani et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, characterization and molecular docking studies of substituted 4-coumarinylpyrano[2,3-c]pyrazole derivatives as potent antibacterial and anti-inflammatory agents

(2017) Bahubali M. Chougala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric, Three-Component, One-Pot Synthesis of Spiropyrazolones and 2,5-Chromenediones from Aldol Condensation/NHC-Catalyzed Annulation Reactions

(2016) Lei Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

A ratiometric fluorescence chemosensor based on a coumarin–pyrazolone hybrid: the synthesis and an investigation of the photophysical, tautomeric and anion binding properties by spectroscopic techniques and DFT calculations

(2015) Banu Babür et al.   TETRAHEDRON LETTERS

In silico binding affinity to cyclooxygenase-II and green synthesis of benzylpyrazolyl coumarin derivatives

(2015) Arijit Saha et al.   RSC Advances

Synthesis and biological evaluation of new pyrazolone–pyridazine conjugates as anti-inflammatory and analgesic agents

(2014) Nadia Abdalla Khalil et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs

(2014) Maria Jose Torres et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

Synthesis, characterization and biological screening of novel 5-imidazopyrazole incorporated fused pyran motifs under microwave irradiation

(2014) Piyush N. Kalaria et al.   NEW JOURNAL OF CHEMISTRY

Serum levels of matrix metalloproteinase-9 predict lymph node metastasis in breast cancer patients

(2014) DONG SIK HEO et al.   ONCOLOGY REPORTS

Detour of prenostodione synthesis towards pyrazolones for antibacterial activity

(2013) Sivappa Rasapalli et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Molecular Dynamics Simulation of Tryptophan Hydroxylase-1: Binding Modes and Free Energy Analysis to Phenylalanine Derivative Inhibitors

(2013) Hao Zhong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antituberculosis and antibacterial evaluations of some novel phenyl pyrazolone-substituted 1h-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine derivatives

(2012) Nikhil M. Parekh et al.   MEDICINAL CHEMISTRY RESEARCH

Pyrone-Based Inhibitors of Metalloproteinase Types 2 and 3 May Work as Conformation-Selective Inhibitors

(2011) Jacob D. Durrant et al.   Chemical Biology & Drug Design