Synthesis, characterization and molecular docking of novel lonazolac analogues 3-(3-hydroxy-5-methyl-1H-pyrazol-4-yl)-3-arylpropanoic acid derivatives: Highly potential COX-1/COX-2, matrix metalloproteinase and protein denaturation inhibitors
出版年份 2022 全文链接
标题
Synthesis, characterization and molecular docking of novel lonazolac analogues 3-(3-hydroxy-5-methyl-1H-pyrazol-4-yl)-3-arylpropanoic acid derivatives: Highly potential COX-1/COX-2, matrix metalloproteinase and protein denaturation inhibitors
作者
关键词
-
出版物
JOURNAL OF MOLECULAR STRUCTURE
Volume 1260, Issue -, Pages 132782
出版商
Elsevier BV
发表日期
2022-03-08
DOI
10.1016/j.molstruc.2022.132782
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Synthesis, Inhibitory Activity, and In Silico Modeling of Selective COX-1 Inhibitors with a Quinazoline Core
- (2021) Marcela Dvorakova et al. ACS Medicinal Chemistry Letters
- Chemical Perspective of the Mechanism of Action of Antiamyloidogenic Compounds Using a Minimalistic Peptide as a Reductionist Model
- (2021) Bharti Koshti et al. ACS Chemical Neuroscience
- Design, synthesis, biological evaluation, and computational studies of novel thiazolo-pyrazole hybrids as promising selective COX-2 inhibitors: Implementation of apoptotic genes expression for ulcerogenic liability assessment
- (2021) Adel A. Marzouk et al. BIOORGANIC CHEMISTRY
- A Compendium of the Most Promising Synthesized Organic Compounds against Several Fusarium oxysporum Species: Synthesis, Antifungal Activity, and Perspectives
- (2021) Paola Borrego-Muñoz et al. MOLECULES
- Indirect, catalyst free β-arylation of acyclic 1,5-dicarbonyl compounds via green method
- (2021) Parashuram Gudimani et al. Chemical Data Collections
- Rational design, synthesis and SAR study of novel warfarin analogous of 4-hydroxy coumarin-beta-aryl propanoic acid derivatives as potent anti-inflammatory agents
- (2021) Varsha Pawar et al. JOURNAL OF MOLECULAR STRUCTURE
- Novel Anticancer Fused Pyrazole Derivatives as EGFR and VEGFR-2 Dual TK Inhibitors
- (2020) Nashwa M. Saleh et al. Frontiers in Chemistry
- The selective condensation of pyrazolones to isatins in aqueous medium
- (2019) Yong Zhang et al. TETRAHEDRON
- Pyrazole, pyrazolone and enaminonitrile pyrazole derivatives: Synthesis, characterization and potential in corrosion inhibition and antimicrobial applications
- (2018) Galal H. Sayed et al. JOURNAL OF MOLECULAR LIQUIDS
- A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly
- (2018) Supakanya Wongrakpanich et al. Aging and Disease
- Tautomerism and antioxidant activity of some 4-acylpyrazolone-based Schiff bases: a theoretical study
- (2018) Esam A. Orabi RSC Advances
- Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6)
- (2017) Gino Cingolani et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, characterization and molecular docking studies of substituted 4-coumarinylpyrano[2,3-c]pyrazole derivatives as potent antibacterial and anti-inflammatory agents
- (2017) Bahubali M. Chougala et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Asymmetric, Three-Component, One-Pot Synthesis of Spiropyrazolones and 2,5-Chromenediones from Aldol Condensation/NHC-Catalyzed Annulation Reactions
- (2016) Lei Wang et al. CHEMISTRY-A EUROPEAN JOURNAL
- A ratiometric fluorescence chemosensor based on a coumarin–pyrazolone hybrid: the synthesis and an investigation of the photophysical, tautomeric and anion binding properties by spectroscopic techniques and DFT calculations
- (2015) Banu Babür et al. TETRAHEDRON LETTERS
- In silico binding affinity to cyclooxygenase-II and green synthesis of benzylpyrazolyl coumarin derivatives
- (2015) Arijit Saha et al. RSC Advances
- Synthesis and biological evaluation of new pyrazolone–pyridazine conjugates as anti-inflammatory and analgesic agents
- (2014) Nadia Abdalla Khalil et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Hypersensitivity Reactions to Nonsteroidal Anti-Inflammatory Drugs
- (2014) Maria Jose Torres et al. IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA
- Synthesis, characterization and biological screening of novel 5-imidazopyrazole incorporated fused pyran motifs under microwave irradiation
- (2014) Piyush N. Kalaria et al. NEW JOURNAL OF CHEMISTRY
- Serum levels of matrix metalloproteinase-9 predict lymph node metastasis in breast cancer patients
- (2014) DONG SIK HEO et al. ONCOLOGY REPORTS
- Detour of prenostodione synthesis towards pyrazolones for antibacterial activity
- (2013) Sivappa Rasapalli et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Molecular Dynamics Simulation of Tryptophan Hydroxylase-1: Binding Modes and Free Energy Analysis to Phenylalanine Derivative Inhibitors
- (2013) Hao Zhong et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Antituberculosis and antibacterial evaluations of some novel phenyl pyrazolone-substituted 1h-benzo[g]pyrazolo[3,4-b]quinoline-3-ylamine derivatives
- (2012) Nikhil M. Parekh et al. MEDICINAL CHEMISTRY RESEARCH
- Pyrone-Based Inhibitors of Metalloproteinase Types 2 and 3 May Work as Conformation-Selective Inhibitors
- (2011) Jacob D. Durrant et al. Chemical Biology & Drug Design
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started