Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6)

Title
Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6)
Authors
Keywords
Cyclooxygenase-1 inhibition, Mofezolac, P6, Diarylisoxazole, X-ray crystallography, Molecular modelling
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 138, Issue -, Pages 661-668
Publisher
Elsevier BV
Online
2017-06-24
DOI
10.1016/j.ejmech.2017.06.045

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