Chemical Perspective of the Mechanism of Action of Antiamyloidogenic Compounds Using a Minimalistic Peptide as a Reductionist Model

In vitro study of the mechanism of intraneuronal β-amyloid aggregation in Alzheimer’s disease

(2020) Shahad Alsunusi et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Coassembly-Induced Transformation of Dipeptide Amyloid-Like Structures into Stimuli-Responsive Supramolecular Materials

(2020) Wei Ji et al.   ACS Nano

Effect of Methionine Diet on Time-Related Metabolic and Histopathological Changes of Rat Hippocampus in the Model of Global Brain Ischemia

(2020) Maria Kovalska et al.   Biomolecules

Trans ε viniferin decreases amyloid deposits and inflammation in a mouse transgenic Alzheimer model

(2019) Martial Caillaud et al.   PLoS One

Hierarchically oriented organization in supramolecular peptide crystals

(2019) Chengqian Yuan et al.   Nature Reviews Chemistry

Charge-Induced Secondary Structure Transformation of Amyloid-Derived Dipeptide Assemblies from β-Sheet to α-Helix

(2018) Ruirui Xing et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer’s Disease

(2018) P. Hemachandra Reddy et al.   JOURNAL OF ALZHEIMERS DISEASE

Antibodies towards Tyrosine Amyloid-Like Fibrils Allow Toxicity Modulation and Cellular Imaging of the Assemblies

(2018) Dor Zaguri et al.   MOLECULES

Amino Acid Based Self-assembled Nanostructures: Complex Structures from Remarkably Simple Building Blocks

(2018) Priyadarshi Chakraborty et al.   ChemNanoMat

Vitamin A has Anti-Oligomerization Effects on Amyloid-β In Vitro

(2018) Junichi Takasaki et al.   JOURNAL OF ALZHEIMERS DISEASE

Amyloid-like Structures Formed by Single Amino Acid Self-Assemblies of Cysteine and Methionine

(2018) Nidhi Gour et al.   ACS Chemical Neuroscience

Amino Acid Coordination Driven Self-Assembly for Enhancing both the Biological Stability and Tumor Accumulation of Curcumin

(2018) Yongxin Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Heteromultivalent peptide recognition by co-assembly of cyclodextrin and calixarene amphiphiles enables inhibition of amyloid fibrillation

(2018) Zhe Xu et al.   Nature Chemistry

Trans-cinnamaldehyde Modulates Hippocampal Nrf2 Factor and Inhibits Amyloid Beta Aggregation in LPS-Induced Neuroinflammation Mouse Model

(2018) Doaa Abou El-ezz et al.   NEUROCHEMICAL RESEARCH

Cysteine as a potential anti-amyloidogenic agent with protective ability against amyloid induced cytotoxicity

(2017) Masihuz Zaman et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Self-assembly of aromatic α-amino acids into amyloid inspired nano/micro scaled architects

(2017) Prabhjot Singh et al.   Materials Science & Engineering C-Materials for Biological Applications

A systemic view of Alzheimer disease — insights from amyloid-β metabolism beyond the brain

(2017) Jun Wang et al.   Nature Reviews Neurology

Construction of protein assemblies by host–guest interactions with cucurbiturils

(2017) Chunxi Hou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Interaction of polymers with amyloidogenic peptides

(2017) Jancy Nixon Abraham et al.   POLYMER INTERNATIONAL

Formation of Apoptosis-Inducing Amyloid Fibrils by Tryptophan

(2016) Shira Shaham-Niv et al.   ISRAEL JOURNAL OF CHEMISTRY

Metabolite amyloids: a new paradigm for inborn error of metabolism disorders

(2016) Ehud Gazit   JOURNAL OF INHERITED METABOLIC DISEASE

Disruption of diphenylalanine assembly by a Boc-modified variant

(2016) Rhiannon C. G. Creasey et al.   Soft Matter

Vitamin k3 inhibits protein aggregation: Implication in the treatment of amyloid diseases

(2016) Parvez Alam et al.   Scientific Reports

Tunable Aggregation-Induced Emission of Tetraphenylethylene via Short Peptide-Directed Self-Assembly

(2016) Kai Liu et al.   Advanced Materials Interfaces

Functional architectures based on self-assembly of bio-inspired dipeptides: Structure modulation and its photoelectronic applications

(2015) Chengjun Chen et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Emerging Concepts in Alzheimer's Disease

(2015) Harry V. Vinters   Annual Review of Pathology-Mechanisms of Disease

Circular Dichroism of Amino Acids: Following the Structural Formation of Phenylalanine

(2015) Nadav Amdursky et al.   CHEMPHYSCHEM

Controlled aggregation of peptide–DNA hybrids into amyloid-like fibrils

(2015) Jancy Nixon Abraham et al.   EUROPEAN POLYMER JOURNAL

Formation of DNA-Copolymer Fibrils Through an Amyloid-Like Nucleation Polymerization Mechanism

(2015) Dawid Kedracki et al.   MACROMOLECULAR RAPID COMMUNICATIONS

The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice

(2015) Angélica Maria Sabogal-Guáqueta et al.   NEUROPHARMACOLOGY

Synthesis and structure formation in dilute aqueous solution of a chitosan-DNA hybrid

(2015) Ilyès Safir et al.   POLYMER

Antroquinonol Lowers Brain Amyloid-β Levels and Improves Spatial Learning and Memory in a Transgenic Mouse Model of Alzheimer’s Disease

(2015) Wen-Han Chang et al.   Scientific Reports

Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects

(2014) Eugenie Nepovimova et al.   JOURNAL OF MEDICINAL CHEMISTRY

β-Amyloid Amorphous Aggregates Induced by the Small Natural Molecule Ferulic Acid

(2013) Emilia Bramanti et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Anti-Infectious Surfaces Achieved by Polymer Modification

(2013) Nidhi Gour et al.   MACROMOLECULAR MATERIALS AND ENGINEERING

Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria

(2012) Lihi Adler-Abramovich et al.   Nature Chemical Biology

Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model

(2012) Siva Sundara Kumar Durairajan et al.   NEUROBIOLOGY OF AGING

Amyloid Structure: Conformational Diversity and Consequences

(2011) Brandon H. Toyama et al.   Annual Review of Biochemistry

Inhibition of amyloid-β aggregation by coumarin analogs can be manipulated by functionalization of the aromatic center

(2011) Deborah D. Soto-Ortega et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Probucol Suppresses Enterocytic Accumulation of Amyloid-β Induced by Saturated Fat and Cholesterol Feeding

(2011) Menuka M. Pallebage-Gamarallage et al.   LIPIDS

Coenzyme Q10 protects against amyloid beta-induced neuronal cell death by inhibiting oxidative stress and activating the P13K pathway

(2011) Hojin Choi et al.   NEUROTOXICOLOGY

Orally Administrated Cinnamon Extract Reduces β-Amyloid Oligomerization and Corrects Cognitive Impairment in Alzheimer's Disease Animal Models

(2011) Anat Frydman-Marom et al.   PLoS One

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Synthesis and self-assembly of a neoglycopeptide: morphological studies and ultrasound-mediated DNA encapsulation

(2010) Nidhi Gour et al.   JOURNAL OF PEPTIDE SCIENCE

Targeting insulin amyloid assembly by small aromatic molecules: Toward rational design of aggregation inhibitors

(2010) Michal Levy-Sakin et al.   Islets

Non-Steroidal Anti-Inflammatory Drugs as Anti-Amyloidogenic Compounds

(2008) Mie Hirohata et al.   CURRENT PHARMACEUTICAL DESIGN